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261  structures 5272  species 14  interactions 27995  sequences 214  architectures

Clan: TKC_like (CL0591)

Summary

Transketolase C-terminal domain-like superfamily Add an annotation

This superfamily is coposed of three branches that include the true C-terminal domains of transketolases, the C-terminal domain of the beta-subunit of branched-chain alpha-keto acid dehydrogenase, and domain II of pyruvate-ferredoxin oxidoreductase, PFOR, family.

This clan contains 4 families and the total number of domains in the clan is 27995. The clan was built by P Coggill.

Members

This clan contains the following 4 member families:

OxoGdeHyase_C PFOR_II Transketolase_C XFP_C

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Transketolase_C (PF02780) 18399 (65.7%) View
PFOR_II (PF17147) 4198 (15.0%) View
OxoGdeHyase_C (PF16870) 3840 (13.7%) View
XFP_C (PF09363) 1558 (5.6%) View
Total: 4 Total: 27995 Clan alignment
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Interactions

There are 14 interactions for this clan. More...

Interacting families
A B
DXP_synthase_N Transketolase_C
E1_dh Transketolase_C
Transket_pyr Transketolase_C
Transketolase_C E1_dh
E3_binding
Transket_pyr
Transketolase_C
Transketolase_N
Transketolase_N Transketolase_C
XFP XFP_C
XFP_C XFP
XFP_C
XFP_N
XFP_N XFP_C

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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