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59  structures 1342  species 10  interactions 7998  sequences 231  architectures

Clan: TRAF (CL0389)

Summary

TRAF domain-like superfamily Add an annotation

Superfamily has a circularly permuted immunoglobulin-fold topology with extra an extra beta-strand. Families include the Math and the SIAH, or Seven in absentia, members.

This clan contains 4 families and the total number of domains in the clan is 7998. The clan was built by P Coggill.

Members

This clan contains the following 4 member families:

MATH Sina zf-TRAF zf-TRAF_2

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
MATH (PF00917) 3428 (42.9%) View
zf-TRAF (PF02176) 2261 (28.3%) View
Sina (PF03145) 2076 (26.0%) View
zf-TRAF_2 (PF15965) 233 (2.9%) View
Total: 4 Total: 7998 Clan alignment
 

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Interactions

There are 10 interactions for this clan. More...

Interacting families
A B
Astacin MATH
BTB MATH
MAM MATH
MATH Herpes_LMP1
MATH
TBD
Sina Siah-Interact_N
Sina
TRADD_N MATH
zf-TRAF zf-TRAF

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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