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136  structures 3513  species 9  interactions 12089  sequences 145  architectures

Clan: TolB_N (CL0342)


TolB, N-terminal domain Add an annotation

Members of this superfamily appear to behave like the N-terminal fold of the TolB transport-portal complex protein, which is beta-stranded.

This clan contains 11 families and the total number of domains in the clan is 12089. The clan was built by A Bateman.


This clan contains the following 11 member families:

ABC_trans_aux CadC_C1 CsgG DUF3280 DUF799 FlgO FlgT_M LpoB LptE NLBH TolB_N

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
LptE (PF04390) 3078 (25.5%) View
ABC_trans_aux (PF03886) 2684 (22.2%) View
TolB_N (PF04052) 2460 (20.3%) View
CsgG (PF03783) 1536 (12.7%) View
LpoB (PF13036) 801 (6.6%) View
FlgO (PF17680) 567 (4.7%) View
DUF799 (PF05643) 353 (2.9%) View
FlgT_M (PF16539) 276 (2.3%) View
DUF3280 (PF11684) 275 (2.3%) View
CadC_C1 (PF18500) 34 (0.3%) View
NLBH (PF05211) 25 (0.2%) View
Total: 11 Total: 12089 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



There are 9 interactions for this clan. More...

Interacting families
ABC_trans_aux ABC_trans_aux
LptE LptE
OmpA TolB_N
PD40 TolB_N


For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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