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36  structures 172  species 1  interaction 2085  sequences 59  architectures

Clan: Vault (CL0666)

Summary

Major Vault Protein repeat superfamily Add an annotation

This superfamily contains the Maor Vault Protein repeat domains.

This clan contains 4 families and the total number of domains in the clan is 2085. The clan was built by A Bateman.

Literature references

  1. Querol-Audi J, Casanas A, Uson I, Luque D, Caston JR, Fita I, Verdaguer N;, EMBO J. 2009;28:3450-3457.: The mechanism of vault opening from the high resolution structure of the N-terminal repeats of MVP. PUBMED:19779459 EPMC:19779459

Members

This clan contains the following 4 member families:

Vault Vault_2 Vault_3 Vault_4

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Vault (PF01505) 1063 (51.0%) View
Vault_2 (PF17794) 478 (22.9%) View
Vault_4 (PF17796) 273 (13.1%) View
Vault_3 (PF17795) 271 (13.0%) View
Total: 4 Total: 2085 Clan alignment
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Interactions

There is 1 interaction for this clan. More...

Interacting families
A B
Vault Vault

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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