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96  structures 942  species 5  interactions 7774  sequences 162  architectures

Clan: gCrystallin (CL0333)


Gamma-Crystallin-like superfamily Add an annotation

This superfamily includes a number of mammalian crystallins as well as ancestral beta gamma-crystallin precursor structures.

This clan contains 8 families and the total number of domains in the clan is 7774. The clan was built by P Coggill.


This clan contains the following 8 member families:

Crystall Crystall_2 Crystall_3 Crystall_4 IL4_i_Ig Inhibitor_I36 MiAMP1 Yeast-kill-tox

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Crystall (PF00030) 6377 (82.0%) View
Inhibitor_I36 (PF03995) 1097 (14.1%) View
Crystall_3 (PF08964) 79 (1.0%) View
Crystall_2 (PF09076) 74 (1.0%) View
Crystall_4 (PF17945) 60 (0.8%) View
MiAMP1 (PF09117) 48 (0.6%) View
IL4_i_Ig (PF18258) 39 (0.5%) View
Yeast-kill-tox (PF09207) 0 (0.0%) View
Total: 8 Total: 7774 Clan alignment

Please note: Clan alignments can be very large and can cause problems for some browsers. Read the note above before viewing.

Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

Tree controls


This tree shows the occurrence of the domains in this clan across different species. More...



There are 5 interactions for this clan. More...

Interacting families
Crystall Crystall
Crystall_3 Crystall_3
RicinB_lectin_2 Crystall


For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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