Summary: Protein of unknown function (DUF2910)
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"DUF" families are annotated with the Domain of unknown function Wikipedia article. This is a general article, with no specific information about individual Pfam DUFs. If you have information about this particular DUF, please let us know using the "Add annotation" button below.
Protein of unknown function (DUF2910) Provide feedback
Some members in this bacterial family annotate the proteins as cytochrome C biogenesis proteins however this cannot be confirmed. Currently no function for this family is known.
Internal database links
|Similarity to PfamA using HHSearch:||LysE|
External database links
- the number of sequences which exhibit this architecture
a textual description of the architecture, e.g. Gla, EGF x 2, Trypsin.
This example describes an architecture with one
Gladomain, followed by two consecutive
EGFdomains, and finally a single
- the UniProt description of the protein sequence
- the number of residues in the sequence
- the Pfam graphic itself.
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This clan contains the nickel transpot family NicO [1-2] and the HupE/UreJ proteins, which may be involved in nickel binding. NicO and HupE contain a conserved GxxHxxxDH motif, which may bind to nickel.
The clan contains the following 6 members:DsbD DsbD_2 DUF2910 HupE_UreJ HupE_UreJ_2 NicO
We make a range of alignments for each Pfam-A family:
- the curated alignment from which the HMM for the family is built
- the alignment generated by searching the sequence database using the HMM
- Representative Proteomes (RPs) at 15%, 35%, 55% and 75% co-membership thresholds
- alignment generated by searching the NCBI sequence database using the family HMM
- alignment generated by searching the metagenomics sequence database using the family HMM
You can see the alignments as HTML or in three different sequence viewers:
- Pfam viewer
- an HTML-based viewer that uses DAS to retrieve alignment fragments on request
1Cannot generate PP/Heatmap alignments for seeds; no PP data available
Key: available, not generated, — not available.
Format an alignment
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Curation and family details
|Seed source:||Pfam-B_001487 (release 23.0)|
|Author:||Pollington J, Finn RD, Eberhardt R|
|Number in seed:||46|
|Number in full:||566|
|Average length of the domain:||215.20 aa|
|Average identity of full alignment:||21 %|
|Average coverage of the sequence by the domain:||94.89 %|
|HMM build commands:||
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||3|
|Download:||download the raw HMM for this family|
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