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576  structures 557  species 0  interactions 102785  sequences 1029  architectures

Family: 7tm_1 (PF00001)

Summary: 7 transmembrane receptor (rhodopsin family)

Pfam includes annotations and additional family information from a range of different sources. These sources can be accessed via the tabs below.

This is the Wikipedia entry entitled "Rhodopsin-like receptors". More...

Rhodopsin-like receptors Edit Wikipedia article

Rhodopsin-like receptors
PDB 1f88 EBI.jpg
Structure of rhodopsin: A G protein-coupled receptor.[1]
Identifiers
Symbol7tm_1
PfamPF00001
Pfam clanGPCR_A
InterProIPR000276
PROSITEPDOC00211
SCOPe1f88 / SUPFAM
OPM superfamily6
OPM protein1gzm
CDDcd00637

Rhodopsin-like receptors are a family of proteins that comprise the largest group of G protein-coupled receptors.[2]

Scope

G-protein-coupled receptors, GPCRs, constitute a vast protein family that encompasses a wide range of functions (including various autocrine, paracrine, and endocrine processes). They show considerable diversity at the sequence level, on the basis of which they can be separated into distinct groups. GPCRs are usually described as "superfamily" because they embrace a group of families for which there are indications of evolutionary relationship, but between which there is no statistically significant similarity in sequence.[2] The currently known superfamily members include the rhodopsin-like GPCRs (this family), the secretin-like GPCRs, the cAMP receptors, the fungal mating pheromone receptors, and the metabotropic glutamate receptor family. There is a specialised database for GPCRs.[3]

Function

The rhodopsin-like GPCRs themselves represent a widespread protein family that includes hormones, neurotransmitters, and light receptors, all of which transduce extracellular signals through interaction with guanine nucleotide-binding (G) proteins. Although their activating ligands vary widely in structure and character, the amino acid sequences of the receptors are very similar and are believed to adopt a common structural framework comprising 7 transmembrane (TM) helices.[4][5][6]

Classes

Rhodopsin-like GPCRs have been classified into the following 19 subgroups (A1-A19) based on a phylogenetic analysis.[7]

Subfamily A1

Subfamily A2

Subfamily A3

Subfamily A4

Subfamily A5

Subfamily A6

Subfamily A7

Subfamily A8

Subfamily A9

Subfamily A10

Subfamily A11

Subfamily A12

Subfamily A13

Subfamily A14

Subfamily A15

Subfamily A16

Subfamily A17

Subfamily A18

Subfamily A19

Unclassified

References

  1. ^ Palczewski K, Kumasaka T, Hori T, et al. (August 2000). "Crystal structure of rhodopsin: A G protein-coupled receptor". Science. 289 (5480): 739–45. doi:10.1126/science.289.5480.739. PMID 10926528.
  2. ^ a b Attwood TK, Findlay JB (1994). "Fingerprinting G-protein-coupled receptors". Protein Eng. 7 (2): 195–203. doi:10.1093/protein/7.2.195. PMID 8170923.
  3. ^ "Information system for G protein-coupled receptors". GPCRDB. www.gpcr.org. Archived from the original on 2009-04-22. Retrieved 2008-12-05.
  4. ^ Birnbaumer L (1990). "G proteins in signal transduction". Annu. Rev. Pharmacol. Toxicol. 30: 675–705. doi:10.1146/annurev.pa.30.040190.003331. PMID 2111655.
  5. ^ Gilman AG, Casey PJ (1988). "G protein involvement in receptor-effector coupling". J. Biol. Chem. 263 (6): 2577–2580. PMID 2830256.
  6. ^ Attwood TK, Findlay JB (1993). "Design of a discriminating fingerprint for G-protein-coupled receptors". Protein Eng. 6 (2): 167–176. doi:10.1093/protein/6.2.167. PMID 8386361.
  7. ^ Joost P, Methner A (2002). "Phylogenetic analysis of 277 human G-protein-coupled receptors as a tool for the prediction of orphan receptor ligands". Genome Biol. 3 (11): research0063.1–0063.16. doi:10.1186/gb-2002-3-11-research0063. PMC 133447. PMID 12429062.
  8. ^ Terakita A (2005). "The opsins". Genome Biol. 6 (3): 213. doi:10.1186/gb-2005-6-3-213. PMC 1088937. PMID 15774036.
  9. ^ a b Nordström KJ, Sällman Almén M, Edstam MM, Fredriksson R, Schiöth HB (September 2011). "Independent HHsearch, Needleman—Wunsch-based, and motif analyses reveal the overall hierarchy for most of the G protein-coupled receptor families". Molecular Biology and Evolution. 28 (9): 2471–80. doi:10.1093/molbev/msr061. PMID 21402729.

External links

This page is based on a Wikipedia article. The text is available under the Creative Commons Attribution/Share-Alike License.

This tab holds the annotation information that is stored in the Pfam database. As we move to using Wikipedia as our main source of annotation, the contents of this tab will be gradually replaced by the Wikipedia tab.

7 transmembrane receptor (rhodopsin family) Provide feedback

This family contains, amongst other G-protein-coupled receptors (GCPRs), members of the opsin family, which have been considered to be typical members of the rhodopsin superfamily. They share several motifs, mainly the seven transmembrane helices, GCPRs of the rhodopsin superfamily. All opsins bind a chromophore, such as 11-cis-retinal. The function of most opsins other than the photoisomerases is split into two steps: light absorption and G-protein activation. Photoisomerases, on the other hand, are not coupled to G-proteins - they are thought to generate and supply the chromophore that is used by visual opsins [1].

Literature references

  1. Terakita A; , Genome Biol 2005;6:213.: The opsins. PUBMED:15774036 EPMC:15774036


Internal database links

External database links

This tab holds annotation information from the InterPro database.

InterPro entry IPR000276

The rhodopsin-like GPCRs (GPCRA) represent a widespread protein family that includes hormone, neurotransmitter and light receptors, all of which transduce extracellular signals through interaction with guanine nucleotide-binding (G) proteins. Although their activating ligands vary widely in structure and character, the amino acid sequences of the receptors are very similar and are believed to adopt a common structural framework comprising 7 transmembrane (TM) helices [ PUBMED:2111655 , PUBMED:2830256 , PUBMED:8386361 ].

G protein-coupled receptors (GPCRs) constitute a vast protein family that encompasses a wide range of functions, including various autocrine, paracrine and endocrine processes. They show considerable diversity at the sequence level, on the basis of which they can be separated into distinct groups [ PUBMED:12679517 ]. The term clan can be used to describe the GPCRs, as they embrace a group of families for which there are indications of evolutionary relationship, but between which there is no statistically significant similarity in sequence [ PUBMED:8170923 ]. The currently known clan members include rhodopsin-like GPCRs (Class A, GPCRA), secretin-like GPCRs (Class B, GPCRB), metabotropic glutamate receptor family (Class C, GPCRC), fungal mating pheromone receptors (Class D, GPCRD), cAMP receptors (Class E, GPCRE) and frizzled/smoothened (Class F, GPCRF) [ PUBMED:8170923 , PUBMED:8081729 , PUBMED:15914470 , PUBMED:18948278 , PUBMED:16753280 ]. GPCRs are major drug targets, and are consequently the subject of considerable research interest. It has been reported that the repertoire of GPCRs for endogenous ligands consists of approximately 400 receptors in humans and mice [ PUBMED:12679517 ]. Most GPCRs are identified on the basis of their DNA sequences, rather than the ligand they bind, those that are unmatched to known natural ligands are designated by as orphan GPCRs, or unclassified GPCRs [ PUBMED:23020293 ].

This entry represents the G protein-coupled receptor, rhodopsin-like family.

Gene Ontology

The mapping between Pfam and Gene Ontology is provided by InterPro. If you use this data please cite InterPro.

Domain organisation

Below is a listing of the unique domain organisations or architectures in which this domain is found. More...

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Pfam Clan

This family is a member of clan GPCR_A (CL0192), which has the following description:

This clan contains various seven-transmembrane receptors and related proteins. A major member is Pfam:PF00001, members of which have been considered to be typical members of the rhodopsin superfamily. Many members of this clan are Caenorhabditis proteins, suggesting great expansion of the relevant families in these nematode worms.

The clan contains the following 45 members:

7TM-7TMR_HD 7tm_1 7tm_2 7tm_3 7tm_4 7TM_GPCR_Sra 7TM_GPCR_Srab 7TM_GPCR_Srb 7TM_GPCR_Srbc 7TM_GPCR_Srd 7TM_GPCR_Srh 7TM_GPCR_Sri 7TM_GPCR_Srj 7TM_GPCR_Srsx 7TM_GPCR_Srt 7TM_GPCR_Sru 7TM_GPCR_Srv 7TM_GPCR_Srw 7TM_GPCR_Srx 7TM_GPCR_Srz 7TM_GPCR_Str 7TMR-DISM_7TM Bac_rhodopsin Ceramidase Dicty_CAR DUF1182 DUF3522 DUF621 Frizzled Git3 GpcrRhopsn4 GPR_Gpa2_C Heliorhodopsin HisKA_7TM HlyIII Lung_7-TM_R Ocular_alb Per1 Pombe_5TM Serpentine_r_xa SID-1_RNA_chan Sre Srg TAS2R V1R

Alignments

We store a range of different sequence alignments for families. As well as the seed alignment from which the family is built, we provide the full alignment, generated by searching the sequence database (reference proteomes) using the family HMM. We also generate alignments using four representative proteomes (RP) sets and the UniProtKB sequence database. More...

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We make a range of alignments for each Pfam-A family. You can see a description of each above. You can view these alignments in various ways but please note that some types of alignment are never generated while others may not be available for all families, most commonly because the alignments are too large to handle.

  Seed
(64)
Full
(102785)
Representative proteomes UniProt
(205672)
RP15
(21690)
RP35
(44821)
RP55
(94353)
RP75
(118218)
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PP/heatmap 1            

1Cannot generate PP/Heatmap alignments for seeds; no PP data available

Key: ✓ available, x not generated, not available.

Format an alignment

  Seed
(64)
Full
(102785)
Representative proteomes UniProt
(205672)
RP15
(21690)
RP35
(44821)
RP55
(94353)
RP75
(118218)
Alignment:
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Order:
Sequence:
Gaps:
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Download options

We make all of our alignments available in Stockholm format. You can download them here as raw, plain text files or as gzip-compressed files.

  Seed
(64)
Full
(102785)
Representative proteomes UniProt
(205672)
RP15
(21690)
RP35
(44821)
RP55
(94353)
RP75
(118218)
Raw Stockholm Download     Download   Download   Download      
Gzipped Download     Download   Download   Download      

You can also download a FASTA format file containing the full-length sequences for all sequences in the full alignment.

HMM logo

HMM logos is one way of visualising profile HMMs. Logos provide a quick overview of the properties of an HMM in a graphical form. You can see a more detailed description of HMM logos and find out how you can interpret them here. More...

Trees

This page displays the phylogenetic tree for this family's seed alignment. We use FastTree to calculate neighbour join trees with a local bootstrap based on 100 resamples (shown next to the tree nodes). FastTree calculates approximately-maximum-likelihood phylogenetic trees from our seed alignment.

Note: You can also download the data file for the tree.

Curation and family details

This section shows the detailed information about the Pfam family. You can see the definitions of many of the terms in this section in the glossary and a fuller explanation of the scoring system that we use in the scores section of the help pages.

Curation View help on the curation process

Seed source: Prosite
Previous IDs: none
Type: Family
Sequence Ontology: SO:0100021
Author: Sonnhammer ELL
Number in seed: 64
Number in full: 102785
Average length of the domain: 253.80 aa
Average identity of full alignment: 18 %
Average coverage of the sequence by the domain: 66.60 %

HMM information View help on HMM parameters

HMM build commands:
build method: hmmbuild -o /dev/null --hand HMM SEED
search method: hmmsearch -Z 57096847 -E 1000 --cpu 4 HMM pfamseq
Model details:
Parameter Sequence Domain
Gathering cut-off 30.5 30.5
Trusted cut-off 30.5 30.5
Noise cut-off 30.4 30.4
Model length: 263
Family (HMM) version: 23
Download: download the raw HMM for this family

Species distribution

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Archea Archea Eukaryota Eukaryota
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Viruses Viruses Unclassified Unclassified
Viroids Viroids Unclassified sequence Unclassified sequence

Selections

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Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe group, to allow us to map Pfam domains onto UniProt sequences and three-dimensional protein structures. The table below shows the structures on which the 7tm_1 domain has been found. There are 576 instances of this domain found in the PDB. Note that there may be multiple copies of the domain in a single PDB structure, since many structures contain multiple copies of the same protein sequence.

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AlphaFold Structure Predictions

The list of proteins below match this family and have AlphaFold predicted structures. Click on the protein accession to view the predicted structure.

Protein Predicted structure External Information
A0A0G2K505 View 3D Structure Click here
A0A0G2K5K9 View 3D Structure Click here
A0A0G2K5Q7 View 3D Structure Click here
A0A0G2KD19 View 3D Structure Click here
A0A0G2KES5 View 3D Structure Click here
A0A0G2KFD8 View 3D Structure Click here
A0A0G2KFR1 View 3D Structure Click here
A0A0G2KIH3 View 3D Structure Click here
A0A0G2KIS6 View 3D Structure Click here
A0A0G2KJF7 View 3D Structure Click here
A0A0G2KJU2 View 3D Structure Click here
A0A0G2KLE8 View 3D Structure Click here
A0A0G2KM61 View 3D Structure Click here
A0A0G2KS15 View 3D Structure Click here
A0A0G2KT85 View 3D Structure Click here
A0A0G2KW99 View 3D Structure Click here
A0A0G2KY14 View 3D Structure Click here
A0A0G2L0R2 View 3D Structure Click here
A0A0G2L0V6 View 3D Structure Click here
A0A0G2L2K4 View 3D Structure Click here
A0A0G2L377 View 3D Structure Click here
A0A0G2L3L2 View 3D Structure Click here
A0A0G2L4S1 View 3D Structure Click here
A0A0G2L7D1 View 3D Structure Click here
A0A0G2L845 View 3D Structure Click here
A0A0G2LAV7 View 3D Structure Click here
A0A0H2UHL4 View 3D Structure Click here
A0A0J9YJL3 View 3D Structure Click here
A0A0K3AXD3 View 3D Structure Click here
A0A0K3AYF5 View 3D Structure Click here
A0A0N4SU25 View 3D Structure Click here
A0A0N4SUG9 View 3D Structure Click here
A0A0N9NKH0 View 3D Structure Click here
A0A0N9NUD7 View 3D Structure Click here
A0A0R3P9B9 View 3D Structure Click here
A0A0R4I9D7 View 3D Structure Click here
A0A0R4I9K1 View 3D Structure Click here
A0A0R4I9M2 View 3D Structure Click here
A0A0R4I9Z4 View 3D Structure Click here
A0A0R4IAN5 View 3D Structure Click here
A0A0R4IAQ2 View 3D Structure Click here
A0A0R4IB14 View 3D Structure Click here
A0A0R4ICV1 View 3D Structure Click here
A0A0R4ID69 View 3D Structure Click here
A0A0R4IDA0 View 3D Structure Click here
A0A0R4IDG1 View 3D Structure Click here
A0A0R4IDZ1 View 3D Structure Click here
A0A0R4IEE2 View 3D Structure Click here
A0A0R4IEG0 View 3D Structure Click here
A0A0R4IEK2 View 3D Structure Click here
A0A0R4IEV3 View 3D Structure Click here
A0A0R4IFY3 View 3D Structure Click here
A0A0R4IH29 View 3D Structure Click here
A0A0R4IHZ4 View 3D Structure Click here
A0A0R4II90 View 3D Structure Click here
A0A0R4IIY1 View 3D Structure Click here
A0A0R4IK12 View 3D Structure Click here
A0A0R4IK53 View 3D Structure Click here
A0A0R4IMA2 View 3D Structure Click here
A0A0R4IMH8 View 3D Structure Click here
A0A0R4IP11 View 3D Structure Click here
A0A0R4IPC6 View 3D Structure Click here
A0A0R4IPI9 View 3D Structure Click here
A0A0R4IQ19 View 3D Structure Click here
A0A0R4IQ80 View 3D Structure Click here
A0A0R4IQJ4 View 3D Structure Click here
A0A0R4IR74 View 3D Structure Click here
A0A0R4IR81 View 3D Structure Click here
A0A0R4IR92 View 3D Structure Click here
A0A0R4ISN1 View 3D Structure Click here
A0A0R4ISV7 View 3D Structure Click here
A0A0R4IT98 View 3D Structure Click here
A0A0R4IUX8 View 3D Structure Click here
A0A0R4IV97 View 3D Structure Click here
A0A0R4IVC9 View 3D Structure Click here
A0A0R4IWV6 View 3D Structure Click here
A0A0R4IYN5 View 3D Structure Click here
A0A0R4IZS2 View 3D Structure Click here
A0A0R4J1Z0 View 3D Structure Click here
A0A140LG78 View 3D Structure Click here
A0A140LG95 View 3D Structure Click here
A0A140LGL6 View 3D Structure Click here
A0A140T8U8 View 3D Structure Click here
A0A1B0GXA3 View 3D Structure Click here
A0A1D5NSD1 View 3D Structure Click here
A0A1D5NSH0 View 3D Structure Click here
A0A1L1QZD6 View 3D Structure Click here
A0A1L1QZF6 View 3D Structure Click here
A0A1L1QZI7 View 3D Structure Click here
A0A1L1QZJ8 View 3D Structure Click here
A0A1L1QZM5 View 3D Structure Click here
A0A1L1QZV7 View 3D Structure Click here
A0A1L1QZV9 View 3D Structure Click here
A0A1W2Q6H2 View 3D Structure Click here
A0A286YAW6 View 3D Structure Click here
A0A286YBK1 View 3D Structure Click here
A0A2C9C3A4 View 3D Structure Click here
A0A2K5ATZ5 View 3D Structure Click here
A0A2K5AU17 View 3D Structure Click here
A0A2R8PXK8 View 3D Structure Click here
A0A2R8PY66 View 3D Structure Click here
A0A2R8PYG6 View 3D Structure Click here
A0A2R8PYH1 View 3D Structure Click here
A0A2R8PYL1 View 3D Structure Click here
A0A2R8PYR8 View 3D Structure Click here
A0A2R8PYU4 View 3D Structure Click here
A0A2R8PZ54 View 3D Structure Click here
A0A2R8PZG3 View 3D Structure Click here
A0A2R8Q030 View 3D Structure Click here
A0A2R8Q1T9 View 3D Structure Click here
A0A2R8Q225 View 3D Structure Click here
A0A2R8Q258 View 3D Structure Click here
A0A2R8Q2F7 View 3D Structure Click here
A0A2R8Q2V0 View 3D Structure Click here
A0A2R8Q434 View 3D Structure Click here
A0A2R8Q495 View 3D Structure Click here
A0A2R8Q4C0 View 3D Structure Click here
A0A2R8Q4G0 View 3D Structure Click here
A0A2R8Q4W6 View 3D Structure Click here
A0A2R8Q5C7 View 3D Structure Click here
A0A2R8Q669 View 3D Structure Click here
A0A2R8Q6D0 View 3D Structure Click here
A0A2R8Q6K5 View 3D Structure Click here
A0A2R8Q6Q3 View 3D Structure Click here
A0A2R8Q767 View 3D Structure Click here
A0A2R8Q772 View 3D Structure Click here
A0A2R8Q7N2 View 3D Structure Click here
A0A2R8Q822 View 3D Structure Click here
A0A2R8Q842 View 3D Structure Click here
A0A2R8Q850 View 3D Structure Click here
A0A2R8Q9U8 View 3D Structure Click here
A0A2R8QAB2 View 3D Structure Click here
A0A2R8QAV6 View 3D Structure Click here
A0A2R8QBL8 View 3D Structure Click here
A0A2R8QBU5 View 3D Structure Click here
A0A2R8QC84 View 3D Structure Click here
A0A2R8QC95 View 3D Structure Click here
A0A2R8QDF5 View 3D Structure Click here
A0A2R8QDM0 View 3D Structure Click here
A0A2R8QEB9 View 3D Structure Click here
A0A2R8QEE9 View 3D Structure Click here
A0A2R8QEF3 View 3D Structure Click here
A0A2R8QEM8 View 3D Structure Click here
A0A2R8QFF3 View 3D Structure Click here
A0A2R8QFN9 View 3D Structure Click here
A0A2R8QFX1 View 3D Structure Click here
A0A2R8QGH2 View 3D Structure Click here
A0A2R8QGN3 View 3D Structure Click here
A0A2R8QGZ0 View 3D Structure Click here
A0A2R8QH78 View 3D Structure Click here
A0A2R8QIW6 View 3D Structure Click here
A0A2R8QIZ2 View 3D Structure Click here
A0A2R8QJ34 View 3D Structure Click here
A0A2R8QJ79 View 3D Structure Click here
A0A2R8QJI2 View 3D Structure Click here
A0A2R8QJP3 View 3D Structure Click here
A0A2R8QL25 View 3D Structure Click here
A0A2R8QM48 View 3D Structure Click here
A0A2R8QNI4 View 3D Structure Click here
A0A2R8QNL3 View 3D Structure Click here
A0A2R8QNR1 View 3D Structure Click here
A0A2R8QNS2 View 3D Structure Click here
A0A2R8QNW0 View 3D Structure Click here
A0A2R8QNW7 View 3D Structure Click here
A0A2R8QP49 View 3D Structure Click here
A0A2R8QPM0 View 3D Structure Click here
A0A2R8QQ23 View 3D Structure Click here
A0A2R8QQ51 View 3D Structure Click here
A0A2R8QQD9 View 3D Structure Click here
A0A2R8QR38 View 3D Structure Click here
A0A2R8QR62 View 3D Structure Click here
A0A2R8QRR2 View 3D Structure Click here
A0A2R8QSK5 View 3D Structure Click here
A0A2R8QSX4 View 3D Structure Click here
A0A2R8QSZ4 View 3D Structure Click here
A0A2R8QUF3 View 3D Structure Click here
A0A2R8RHH7 View 3D Structure Click here
A0A2R8RIP4 View 3D Structure Click here
A0A2R8RJ90 View 3D Structure Click here
A0A2R8RJT7 View 3D Structure Click here
A0A2R8RJX0 View 3D Structure Click here
A0A2R8RKN1 View 3D Structure Click here
A0A2R8RL91 View 3D Structure Click here
A0A2R8RLM4 View 3D Structure Click here
A0A2R8RMF6 View 3D Structure Click here
A0A2R8RS43 View 3D Structure Click here
A0A2R8RS79 View 3D Structure Click here
A0A2R8RSR3 View 3D Structure Click here
A0A2R8RUM5 View 3D Structure Click here
A0A2R8RUT9 View 3D Structure Click here
A0A2R8RUU3 View 3D Structure Click here
A0A2R8RVU6 View 3D Structure Click here
A0A2R8RW13 View 3D Structure Click here
A0A2R8RW62 View 3D Structure Click here
A0A2R8RWD4 View 3D Structure Click here
A0A2R8RWN7 View 3D Structure Click here
A0A2R9YJI3 View 3D Structure Click here
A0A2R9YJM5 View 3D Structure Click here
A0A2R9YJN7 View 3D Structure Click here
A0A3B1DQQ4 View 3D Structure Click here
A0A486WX37 View 3D Structure Click here
A0A486WXM4 View 3D Structure Click here
A0A668KM38 View 3D Structure Click here
A0JMI2 View 3D Structure Click here
A0PJR8 View 3D Structure Click here
A0PJS0 View 3D Structure Click here
A0T2N3 View 3D Structure Click here
A1A5S3 View 3D Structure Click here
A1A5V5 View 3D Structure Click here
A1YQE3 View 3D Structure Click here
A1Z7X3 View 3D Structure Click here
A1ZAX0 View 3D Structure Click here
A2AR72 View 3D Structure Click here
A2ARI4 View 3D Structure Click here
A2AV71 View 3D Structure Click here
A2BGL6 View 3D Structure Click here
A2BHH9 View 3D Structure Click here
A2BHL6 View 3D Structure Click here
A2BIP6 View 3D Structure Click here
A2V8C4 View 3D Structure Click here
A3KGQ1 View 3D Structure Click here
A3KNW1 View 3D Structure Click here
A3KPR9 View 3D Structure Click here
A3QJX7 View 3D Structure Click here
A3QJZ0 View 3D Structure Click here
A4FUN8 View 3D Structure Click here
A4FUQ5 View 3D Structure Click here
A4IG54 View 3D Structure Click here
A5PLE7 View 3D Structure Click here
A5PMT9 View 3D Structure Click here
A5WWC0 View 3D Structure Click here
A6NFC9 View 3D Structure Click here
A6QR73 View 3D Structure Click here
A7ISD5 View 3D Structure Click here
A8E7L5 View 3D Structure Click here
A8E7S9 View 3D Structure Click here
A8E7T8 View 3D Structure Click here
A8JUP8 View 3D Structure Click here
A8YXX6 View 3D Structure Click here
A9JRC2 View 3D Structure Click here
A9JRH6 View 3D Structure Click here
A9NJI7 View 3D Structure Click here
B0R167 View 3D Structure Click here
B0S5B5 View 3D Structure Click here
B0S6P9 View 3D Structure Click here
B0S6Q0 View 3D Structure Click here
B0S6X1 View 3D Structure Click here
B0S7I8 View 3D Structure Click here
B0UXR0 View 3D Structure Click here
B0UXR1 View 3D Structure Click here
B0V116 View 3D Structure Click here
B0V1I9 View 3D Structure Click here
B0V1K7 View 3D Structure Click here
B0V1P1 View 3D Structure Click here
B0V2S3 View 3D Structure Click here
B0YIR8 View 3D Structure Click here
B1NYI2 View 3D Structure Click here
B1NYI3 View 3D Structure Click here
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