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643  structures 3993  species 0  interactions 31016  sequences 439  architectures

Family: GST_C (PF00043)

Summary: Glutathione S-transferase, C-terminal domain

Pfam includes annotations and additional family information from a range of different sources. These sources can be accessed via the tabs below.

This is the Wikipedia entry entitled "Glutathione S-transferase, C-terminal domain". More...

Glutathione S-transferase, C-terminal domain Edit Wikipedia article

Glutathione S-transferase, C-terminal domain
PDB 1z9h EBI.jpg
Identifiers
SymbolGST_C
PfamPF00043
InterProIPR004046
SCOPe2gst / SUPFAM
OPM superfamily131
OPM protein1z9h
CDDcd00299

Glutathione S-transferase, C-terminal domain is a structural domain of glutathione S-transferase (GST).

GST conjugates reduced glutathione to a variety of targets including S-crystallin from squid, the eukaryotic elongation factor 1-gamma, the HSP26 family of stress-related proteins and auxin-regulated proteins in plants.

The glutathione molecule binds in a cleft between N and C-terminal domains. The catalytically important residues are proposed to reside in the N-terminal domain. In plants, GSTs are encoded by a large gene family (48 GST genes in Arabidopsis) and can be divided into the phi, tau, theta, zeta, and lambda classes.

Biological function and classification

In eukaryotes, glutathione S-transferases (GSTs) participate in the detoxification of reactive electrophilic compounds by catalysing their conjugation to glutathione. The GST domain is also found in S-crystallins from squid, and proteins with no known GST activity, such as eukaryotic elongation factors 1-gamma and the HSP26 family of stress-related proteins, which include auxin-regulated proteins in plants and stringent starvation proteins in Escherichia coli. The major lens polypeptide of cephalopods is also a GST.[1][2][3][4]

Bacterial GSTs of known function often have a specific, growth-supporting role in biodegradative metabolism: epoxide ring opening and tetrachlorohydroquinone reductive dehalogenation are two examples of the reactions catalysed by these bacterial GSTs. Some regulatory proteins, like the stringent starvation proteins, also belong to the GST family.[5][6] GST seems to be absent from Archaea in which gamma-glutamylcysteine substitute to glutathione as major thiol.

Oligomerization

Glutathione S-transferases form homodimers, but in eukaryotes can also form heterodimers of the A1 and A2 or YC1 and YC2 subunits. The homodimeric enzymes display a conserved structural fold. Each monomer is composed of a distinct N-terminal sub-domain, which adopts the thioredoxin fold, and a C-terminal all-helical sub-domain. This entry is the C-terminal domain.

Human proteins containing this domain

EEF1E1; EEF1G; GDAP1; GSTA1; GSTA2; GSTA3; GSTA4; GSTA5; GSTM1; GSTM2; GSTM3; GSTM4; GSTM5; GSTO1; GSTP1; GSTT1; GSTT2; GSTZ1; MARS; PGDS; PTGDS2; PTGES2; VARS;

References

  1. ^ Armstrong RN (1997). "Structure, Catalytic Mechanism, and Evolution of the Glutathione Transferases". Chemical Research in Toxicology. 10 (1): 2–18. doi:10.1021/tx960072x. PMID 9074797.
  2. ^ Board PG, Coggan M, Chelvanayagam G, Easteal S, Jermiin LS, Schulte GK, Danley DE, Hoth LR, Griffor MC, Kamath AV, Rosner MH, Chrunyk BA, Perregaux DE, Gabel CA, Geoghegan KF, Pandit J (2000). "Identification, Characterization, and Crystal Structure of the Omega Class Glutathione Transferases". Journal of Biological Chemistry. 275 (32): 24798–24806. doi:10.1074/jbc.M001706200. PMID 10783391.
  3. ^ Dulhunty A, Gage P, Curtis S, Chelvanayagam G, Board P (2000). "The Glutathione Transferase Structural Family Includes a Nuclear Chloride Channel and a Ryanodine Receptor Calcium Release Channel Modulator". Journal of Biological Chemistry. 276 (5): 3319–3323. doi:10.1074/jbc.M007874200. PMID 11035031.
  4. ^ Eaton DL, Bammler TK; Bammler (1999). "Concise review of the glutathione S-transferases and their significance to toxicology". Toxicological Sciences. 49 (2): 156–164. doi:10.1093/toxsci/49.2.156. PMID 10416260.
  5. ^ Polekhina G, Board PG, Blackburn AC, Parker MW (2001). "Crystal structure of maleylacetoacetate isomerase/glutathione transferase zeta reveals the molecular basis for its remarkable catalytic promiscuity". Biochemistry. 40 (6): 1567–1576. doi:10.1021/bi002249z. PMID 11327815.
  6. ^ Vuilleumier S (1997). "Bacterial glutathione S-transferases: What are they good for?". Journal of Bacteriology. 179 (5): 1431–1441. doi:10.1128/jb.179.5.1431-1441.1997. PMC 178850. PMID 9045797.

Further reading

  • [1], GST Gene Fusion System Handbook by GE Healthcare Life Sciences

This page is based on a Wikipedia article. The text is available under the Creative Commons Attribution/Share-Alike License.

This tab holds the annotation information that is stored in the Pfam database. As we move to using Wikipedia as our main source of annotation, the contents of this tab will be gradually replaced by the Wikipedia tab.

Glutathione S-transferase, C-terminal domain Provide feedback

GST conjugates reduced glutathione to a variety of targets including S-crystallin from squid, the eukaryotic elongation factor 1-gamma, the HSP26 family of stress-related proteins and auxin-regulated proteins in plants. Stringent starvation proteins in E. coli are also included in the alignment but are not known to have GST activity. The glutathione molecule binds in a cleft between N and C-terminal domains. The catalytically important residues are proposed to reside in the N-terminal domain [1]. In plants, GSTs are encoded by a large gene family (48 GST genes in Arabidopsis) and can be divided into the phi, tau, theta, zeta, and lambda classes [2].

Literature references

  1. Nishida M, Harada S, Noguchi S, Satow Y, Inoue H, Takahashi K; , J Mol Biol 1998;281:135-147.: Three-dimensional structure of Escherichia coli glutathione S-transferase complexed with glutathione sulfonate: catalytic roles of Cys10 and His106. PUBMED:9680481 EPMC:9680481

  2. Dixon DP, Lapthorn A, Edwards R; , Genome Biol 2002;3:REVIEWS3004.: Plant glutathione transferases. PUBMED:11897031 EPMC:11897031


Internal database links

External database links

This tab holds annotation information from the InterPro database.

InterPro entry IPR004046

In eukaryotes, glutathione S-transferases (GSTs) participate in the detoxification of reactive electrophilic compounds by catalysing their conjugation to glutathione. The GST domain is also found in S-crystallins from squid, and proteins with no known GST activity, such as eukaryotic elongation factors 1-gamma and the HSP26 family of stress-related proteins, which include auxin-regulated proteins in plants and stringent starvation proteins in Escherichia coli. The major lens polypeptide of cephalopods is also a GST [ PUBMED:9074797 , PUBMED:10783391 , PUBMED:11035031 , PUBMED:10416260 ].

Bacterial GSTs of known function often have a specific, growth-supporting role in biodegradative metabolism: epoxide ring opening and tetrachlorohydroquinone reductive dehalogenation are two examples of the reactions catalysed by these bacterial GSTs. Some regulatory proteins, like the stringent starvation proteins, also belong to the GST family [ PUBMED:11327815 , PUBMED:9045797 ]. GST seems to be absent from Archaea in which gamma-glutamylcysteine substitute to glutathione as major thiol.

Glutathione S-transferases form homodimers, but in eukaryotes can also form heterodimers of the A1 and A2 or YC1 and YC2 subunits. The homodimeric enzymes display a conserved structural fold. Each monomer is composed of a distinct N-terminal sub-domain, which adopts the thioredoxin fold, and a C-terminal all-helical sub-domain. This entry is the C-terminal domain.

Domain organisation

Below is a listing of the unique domain organisations or architectures in which this domain is found. More...

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Pfam Clan

This family is a member of clan GST_C (CL0497), which has the following description:

This clan represents the C-terminal domain of Glutathione S-transferase.

The clan contains the following 8 members:

Glutaredoxin2_C GST_C GST_C_2 GST_C_3 GST_C_4 GST_C_5 GST_C_6 Tom37_C

Alignments

We store a range of different sequence alignments for families. As well as the seed alignment from which the family is built, we provide the full alignment, generated by searching the sequence database (reference proteomes) using the family HMM. We also generate alignments using four representative proteomes (RP) sets and the UniProtKB sequence database. More...

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We make a range of alignments for each Pfam-A family. You can see a description of each above. You can view these alignments in various ways but please note that some types of alignment are never generated while others may not be available for all families, most commonly because the alignments are too large to handle.

  Seed
(34)
Full
(31016)
Representative proteomes UniProt
(105172)
RP15
(3889)
RP35
(13612)
RP55
(27084)
RP75
(45637)
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PP/heatmap 1            

1Cannot generate PP/Heatmap alignments for seeds; no PP data available

Key: ✓ available, x not generated, not available.

Format an alignment

  Seed
(34)
Full
(31016)
Representative proteomes UniProt
(105172)
RP15
(3889)
RP35
(13612)
RP55
(27084)
RP75
(45637)
Alignment:
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We make all of our alignments available in Stockholm format. You can download them here as raw, plain text files or as gzip-compressed files.

  Seed
(34)
Full
(31016)
Representative proteomes UniProt
(105172)
RP15
(3889)
RP35
(13612)
RP55
(27084)
RP75
(45637)
Raw Stockholm Download   Download   Download   Download   Download   Download   Download  
Gzipped Download   Download   Download   Download   Download   Download   Download  

You can also download a FASTA format file containing the full-length sequences for all sequences in the full alignment.

HMM logo

HMM logos is one way of visualising profile HMMs. Logos provide a quick overview of the properties of an HMM in a graphical form. You can see a more detailed description of HMM logos and find out how you can interpret them here. More...

Trees

This page displays the phylogenetic tree for this family's seed alignment. We use FastTree to calculate neighbour join trees with a local bootstrap based on 100 resamples (shown next to the tree nodes). FastTree calculates approximately-maximum-likelihood phylogenetic trees from our seed alignment.

Note: You can also download the data file for the tree.

Curation and family details

This section shows the detailed information about the Pfam family. You can see the definitions of many of the terms in this section in the glossary and a fuller explanation of the scoring system that we use in the scores section of the help pages.

Curation View help on the curation process

Seed source: Overington
Previous IDs: gluts; GST;
Type: Domain
Sequence Ontology: SO:0000417
Author: Eddy SR , Griffiths-Jones SR
Number in seed: 34
Number in full: 31016
Average length of the domain: 96.60 aa
Average identity of full alignment: 17 %
Average coverage of the sequence by the domain: 34.85 %

HMM information View help on HMM parameters

HMM build commands:
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 57096847 -E 1000 --cpu 4 HMM pfamseq
Model details:
Parameter Sequence Domain
Gathering cut-off 20.7 20.7
Trusted cut-off 20.7 20.7
Noise cut-off 20.6 20.6
Model length: 93
Family (HMM) version: 27
Download: download the raw HMM for this family

Species distribution

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Viroids Viroids Unclassified sequence Unclassified sequence

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Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe group, to allow us to map Pfam domains onto UniProt sequences and three-dimensional protein structures. The table below shows the structures on which the GST_C domain has been found. There are 643 instances of this domain found in the PDB. Note that there may be multiple copies of the domain in a single PDB structure, since many structures contain multiple copies of the same protein sequence.

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AlphaFold Structure Predictions

The list of proteins below match this family and have AlphaFold predicted structures. Click on the protein accession to view the predicted structure.

Protein Predicted structure External Information
A0A0B5E2M0 View 3D Structure Click here
A0A0B5E8V1 View 3D Structure Click here
A0A0B5EC24 View 3D Structure Click here
A0A0G2JTB1 View 3D Structure Click here
A0A0G2K3C6 View 3D Structure Click here
A0A0P0V328 View 3D Structure Click here
A0A0P0V6Z0 View 3D Structure Click here
A0A0P0VCV3 View 3D Structure Click here
A0A0P0VZU7 View 3D Structure Click here
A0A0P0XQK1 View 3D Structure Click here
A0A0P0XWH4 View 3D Structure Click here
A0A0P0XX30 View 3D Structure Click here
A0A0R0EYZ6 View 3D Structure Click here
A0A0R0F1I6 View 3D Structure Click here
A0A0R0GD17 View 3D Structure Click here
A0A0R0IQJ4 View 3D Structure Click here
A0A0R0J837 View 3D Structure Click here
A0A0R0JE00 View 3D Structure Click here
A0A0R0KCZ2 View 3D Structure Click here
A0A1D6H6Y0 View 3D Structure Click here
A0A1D6JMY2 View 3D Structure Click here
A0A1D6JMZ6 View 3D Structure Click here
A0A1D6JNB0 View 3D Structure Click here
A0A1D6K7T4 View 3D Structure Click here
A0A1D6K7U0 View 3D Structure Click here
A0A1D6K7U3 View 3D Structure Click here
A0A1D6LSP2 View 3D Structure Click here
A0A1D6N1E3 View 3D Structure Click here
A0A1D6N1E7 View 3D Structure Click here
A0A1D6N1E9 View 3D Structure Click here
A0A1D6NMS9 View 3D Structure Click here
A0A1D6QQD4 View 3D Structure Click here
A0A1D8PKC3 View 3D Structure Click here
A0A1D8PMP7 View 3D Structure Click here
A0A1D8PNN8 View 3D Structure Click here
A0A1D8PQL8 View 3D Structure Click here
A0A1D8PT82 View 3D Structure Click here
A0A1W2PR19 View 3D Structure Click here
A0A1W2PRG0 View 3D Structure Click here
A0A2R8QDF0 View 3D Structure Click here
A0A2R8QRW5 View 3D Structure Click here
A0A2R8RKA3 View 3D Structure Click here
A0A5K1K967 View 3D Structure Click here
A1Z7X7 View 3D Structure Click here
A1ZB68 View 3D Structure Click here
A1ZB69 View 3D Structure Click here
A1ZB71 View 3D Structure Click here
A1ZB72 View 3D Structure Click here
A1ZB73 View 3D Structure Click here
A2ZT76 View 3D Structure Click here
A4HU18 View 3D Structure Click here
A4HU19 View 3D Structure Click here
A4I925 View 3D Structure Click here
B0BN47 View 3D Structure Click here
B0G141 View 3D Structure Click here
B2RYN3 View 3D Structure Click here
B4FGR9 View 3D Structure Click here
B4FK84 View 3D Structure Click here
B4FSR6 View 3D Structure Click here
B4FV03 View 3D Structure Click here
B5BP46 View 3D Structure Click here
B6SKA0 View 3D Structure Click here
B6SZY7 View 3D Structure Click here
B6T7G7 View 3D Structure Click here
B6T7H0 View 3D Structure Click here
B6TL20 View 3D Structure Click here
B6U5S1 View 3D Structure Click here
B6U9Z8 View 3D Structure Click here
B8A2B5 View 3D Structure Click here
C6SVD7 View 3D Structure Click here
C6T188 View 3D Structure Click here
C6T460 View 3D Structure Click here
C6TKS0 View 3D Structure Click here
C6TNT2 View 3D Structure Click here
D3Z941 View 3D Structure Click here
D7SFI3 View 3D Structure Click here
E1JJS1 View 3D Structure Click here
E7EZ94 View 3D Structure Click here
E9Q6L7 View 3D Structure Click here
F1Q740 View 3D Structure Click here
F1QBZ6 View 3D Structure Click here
F1QN63 View 3D Structure Click here
F1QP23 View 3D Structure Click here
F1QVE4 View 3D Structure Click here
I1J727 View 3D Structure Click here
I1JBT3 View 3D Structure Click here
I1JBT5 View 3D Structure Click here
I1JFH4 View 3D Structure Click here
I1JFH5 View 3D Structure Click here
I1KK55 View 3D Structure Click here
I1KK57 View 3D Structure Click here
I1KK59 View 3D Structure Click here
I1KK63 View 3D Structure Click here
I1KK66 View 3D Structure Click here
I1KK68 View 3D Structure Click here
I1KNS9 View 3D Structure Click here
I1KSG7 View 3D Structure Click here
I1KU83 View 3D Structure Click here
I1KXZ0 View 3D Structure Click here
I1L7W8 View 3D Structure Click here
I1LAX4 View 3D Structure Click here
I1LCH6 View 3D Structure Click here
I1LM81 View 3D Structure Click here
I1LTA4 View 3D Structure Click here
I1LYR7 View 3D Structure Click here
I1MBR1 View 3D Structure Click here
I1MQS6 View 3D Structure Click here
I1MRZ9 View 3D Structure Click here
I1N104 View 3D Structure Click here
I1N2P4 View 3D Structure Click here
I1N2P6 View 3D Structure Click here
I1NES7 View 3D Structure Click here
I1NF36 View 3D Structure Click here
K7KBA9 View 3D Structure Click here
K7KBB0 View 3D Structure Click here
K7KDM7 View 3D Structure Click here
K7L1L7 View 3D Structure Click here
K7L1M0 View 3D Structure Click here
K7LYT1 View 3D Structure Click here
K7LZF2 View 3D Structure Click here
K7M4P2 View 3D Structure Click here
K7MRB1 View 3D Structure Click here
K7VHH0 View 3D Structure Click here
O04487 View 3D Structure Click here
O09131 View 3D Structure Click here
O17234 View 3D Structure Click here
O43324 View 3D Structure Click here
O45352 View 3D Structure Click here
O59827 View 3D Structure Click here
O65857 View 3D Structure Click here
O74830 View 3D Structure Click here
O80852 View 3D Structure Click here
O82451 View 3D Structure Click here
O82462 View 3D Structure Click here
P04907 View 3D Structure Click here
P07814 View 3D Structure Click here
P08010 View 3D Structure Click here
P08263 View 3D Structure Click here
P09210 View 3D Structure Click here
P0A9D2 View 3D Structure Click here
P0ACA1 View 3D Structure Click here
P0ACA3 View 3D Structure Click here
P0ACA7 View 3D Structure Click here
P0CG29 View 3D Structure Click here
P0CG30 View 3D Structure Click here
P10299 View 3D Structure Click here
P10648 View 3D Structure Click here
P12653 View 3D Structure Click here
P13745 View 3D Structure Click here
P15626 View 3D Structure Click here
P20432 View 3D Structure Click here
P21266 View 3D Structure Click here
P23202 View 3D Structure Click here
P24472 View 3D Structure Click here
P26640 View 3D Structure Click here
P26641 View 3D Structure Click here
P28161 View 3D Structure Click here
P29547 View 3D Structure Click here
P30115 View 3D Structure Click here
P30711 View 3D Structure Click here
P30713 View 3D Structure Click here
P32110 View 3D Structure Click here
P34277 View 3D Structure Click here
P34345 View 3D Structure Click here
P36008 View 3D Structure Click here
P40582 View 3D Structure Click here
P40921 View 3D Structure Click here
P41043 View 3D Structure Click here
P42760 View 3D Structure Click here
P42761 View 3D Structure Click here
P42936 View 3D Structure Click here
P46417 View 3D Structure Click here
P46420 View 3D Structure Click here
P46422 View 3D Structure Click here
P48774 View 3D Structure Click here
P54412 View 3D Structure Click here
P56192 View 3D Structure Click here
P77526 View 3D Structure Click here
Q01579 View 3D Structure Click here
Q04462 View 3D Structure Click here
Q0DVD9 View 3D Structure Click here
Q0JMX6 View 3D Structure Click here
Q12390 View 3D Structure Click here
Q2QYE4 View 3D Structure Click here
Q32PX2 View 3D Structure Click here
Q4CWR8 View 3D Structure Click here
Q4CXW2 View 3D Structure Click here
Q4DAK3 View 3D Structure Click here
Q4DH08 View 3D Structure Click here
Q4DLA7 View 3D Structure Click here
Q4DZ48 View 3D Structure Click here
Q4V8E6 View 3D Structure Click here
Q54B85 View 3D Structure Click here
Q54JU2 View 3D Structure Click here
Q54KB8 View 3D Structure Click here
Q555N6 View 3D Structure Click here
Q59QS1 View 3D Structure Click here
Q5AFB4 View 3D Structure Click here
Q5BK56 View 3D Structure Click here
Q5JKX6 View 3D Structure Click here
Q5JKY3 View 3D Structure Click here
Q5JKY4 View 3D Structure Click here
Q5Z627 View 3D Structure Click here
Q5ZC86 View 3D Structure Click here
Q5ZCX6 View 3D Structure Click here
Q61133 View 3D Structure Click here
Q64471 View 3D Structure Click here
Q65XF1 View 3D Structure Click here
Q68FL6 View 3D Structure Click here
Q68FR6 View 3D Structure Click here
Q6DGL3 View 3D Structure Click here
Q6NP69 View 3D Structure Click here
Q6P8Q0 View 3D Structure Click here
Q6PE25 View 3D Structure Click here
Q6QN18 View 3D Structure Click here
Q6YW46 View 3D Structure Click here
Q7JVI6 View 3D Structure Click here
Q7JVZ8 View 3D Structure Click here
Q7JYX0 View 3D Structure Click here
Q7JYZ9 View 3D Structure Click here
Q7K0B6 View 3D Structure Click here
Q7K8X7 View 3D Structure Click here
Q7KK90 View 3D Structure Click here
Q7XCK0 View 3D Structure Click here
Q7XDA6 View 3D Structure Click here
Q84TK0 View 3D Structure Click here
Q869Z5 View 3D Structure Click here
Q86AH6 View 3D Structure Click here
Q8CGC7 View 3D Structure Click here
Q8H8D6 View 3D Structure Click here
Q8H8D8 View 3D Structure Click here
Q8H8E0 View 3D Structure Click here
Q8LR62 View 3D Structure Click here
Q8MKK1 View 3D Structure Click here
Q8R010 View 3D Structure Click here
Q8RUJ2 View 3D Structure Click here
Q8RUP8 View 3D Structure Click here
Q8S703 View 3D Structure Click here
Q8S715 View 3D Structure Click here
Q8S718 View 3D Structure Click here
Q8SSU2 View 3D Structure Click here
Q93VX8 View 3D Structure Click here
Q93WM2 View 3D Structure Click here
Q93WY5 View 3D Structure Click here
Q945W3 View 3D Structure Click here
Q96266 View 3D Structure Click here
Q96324 View 3D Structure Click here
Q96WL3 View 3D Structure Click here
Q99L20 View 3D Structure Click here
Q9AS47 View 3D Structure Click here
Q9AS59 View 3D Structure Click here
Q9C6C8 View 3D Structure Click here
Q9D1M4 View 3D Structure Click here
Q9D4P7 View 3D Structure Click here
Q9D8N0 View 3D Structure Click here
Q9FE46 View 3D Structure Click here
Q9FQA3 View 3D Structure Click here
Q9FQA5 View 3D Structure Click here
Q9FQB5 View 3D Structure Click here
Q9FQC3 View 3D Structure Click here
Q9FQC4 View 3D Structure Click here
Q9FQC6 View 3D Structure Click here
Q9FQC7 View 3D Structure Click here
Q9FQD0 View 3D Structure Click here
Q9FQD4 View 3D Structure Click here
Q9FQD8 View 3D Structure Click here
Q9FQD9 View 3D Structure Click here
Q9FQE1 View 3D Structure Click here
Q9FQE5 View 3D Structure Click here
Q9FQE7 View 3D Structure Click here
Q9FQF3 View 3D Structure Click here
Q9FUE1 View 3D Structure Click here
Q9FUS6 View 3D Structure Click here
Q9FUS8 View 3D Structure Click here
Q9FUS9 View 3D Structure Click here
Q9FVT2 View 3D Structure Click here
Q9LQ48 View 3D Structure Click here
Q9LZI9 View 3D Structure Click here
Q9NJH0 View 3D Structure Click here
Q9P6M1 View 3D Structure Click here
Q9SLM6 View 3D Structure Click here
Q9SR36 View 3D Structure Click here
Q9SRY5 View 3D Structure Click here
Q9SRY6 View 3D Structure Click here
Q9VG92 View 3D Structure Click here
Q9VG93 View 3D Structure Click here
Q9VG94 View 3D Structure Click here
Q9VG95 View 3D Structure Click here
Q9VG96 View 3D Structure Click here
Q9VG97 View 3D Structure Click here
Q9VG98 View 3D Structure Click here
Q9VGA0 View 3D Structure Click here
Q9VGA1 View 3D Structure Click here
Q9VRJ3 View 3D Structure Click here
Q9XIF8 View 3D Structure Click here
Q9XYZ9 View 3D Structure Click here
Q9Y7Q2 View 3D Structure Click here
Q9Z1B2 View 3D Structure Click here
Q9Z1Q9 View 3D Structure Click here
Q9Z339 View 3D Structure Click here
Q9ZRI7 View 3D Structure Click here
Q9ZW24 View 3D Structure Click here
Q9ZW30 View 3D Structure Click here