Summary: Fatty acid synthesis protein
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Fatty acid synthesis protein Provide feedback
The plsX gene is part of the bacterial fab gene cluster which encodes several key fatty acid biosynthetic enzymes . The exact function of the plsX protein in fatty acid synthesis is unknown.
Zhang Y, Cronan JE Jr; , J Bacteriol 1998;180:3295-3303.: Transcriptional analysis of essential genes of the Escherichia coli fatty acid biosynthesis gene cluster by functional replacement with the analogous Salmonella typhimurium gene cluster. PUBMED:9642179 EPMC:9642179
External database links
This tab holds annotation information from the InterPro database.
InterPro entry IPR003664The plsX gene is part of the bacterial fab gene cluster which encodes several key fatty acid biosynthetic enzymes [PUBMED:9642179]. The plsX gene encodes a poorly understood enzyme of phospholipid metabolism [PUBMED:10464226].
The mapping between Pfam and Gene Ontology is provided by InterPro. If you use this data please cite InterPro.
|Molecular function||catalytic activity (GO:0003824)|
|Biological process||fatty acid biosynthetic process (GO:0006633)|
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Curation and family details
|Seed source:||Pfam-B_1671 (release 5.4)|
|Author:||Mian N, Bateman A|
|Number in seed:||11|
|Number in full:||3673|
|Average length of the domain:||315.60 aa|
|Average identity of full alignment:||40 %|
|Average coverage of the sequence by the domain:||93.65 %|
|HMM build commands:||
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||10|
|Download:||download the raw HMM for this family|
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For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe group, to allow us to map Pfam domains onto UniProt sequences and three-dimensional protein structures. The table below shows the structures on which the FA_synthesis domain has been found. There are 4 instances of this domain found in the PDB. Note that there may be multiple copies of the domain in a single PDB structure, since many structures contain multiple copies of the same protein seqence.
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