# STOCKHOLM 1.0
#=GF ID   RSN1_7TM
#=GF AC   PF02714.16
#=GF DE   Calcium-dependent channel, 7TM region, putative phosphate
#=GF PI   DUF221;
#=GF AU   Bashton M;0000-0002-6847-1525
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF SE   Pfam-B_1596 (release 5.5)
#=GF GA   28.70 28.70;
#=GF TC   28.70 28.70;
#=GF NC   28.60 28.60;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 47079205 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   17005914
#=GF RT   The yeast tumor suppressor homologue Sro7p is required for
#=GF RT   targeting of the sodium pumping ATPase to the cell surface.
#=GF RA   Wadskog I, Forsmark A, Rossi G, Konopka C, Oyen M, Goksor M,
#=GF RA   Ronne H, Brennwald P, Adler L;
#=GF RL   Mol Biol Cell. 2006;17:4988-5003.
#=GF RN   [2]
#=GF RM   18552845
#=GF RT   Integrating large-scale functional genomic data to dissect the
#=GF RT   complexity of yeast regulatory networks.
#=GF RA   Zhu J, Zhang B, Smith EN, Drees B, Brem RB, Kruglyak L,
#=GF RA   Bumgarner RE, Schadt EE;
#=GF RL   Nat Genet. 2008;40:854-861.
#=GF RN   [3]
#=GF RM   24503647
#=GF RT   DUF221 proteins are a family of osmosensitive calcium-permeable
#=GF RT   cation channels conserved across eukaryotes.
#=GF RA   Hou C, Tian W, Kleist T, He K, Garcia V, Bai F, Hao Y, Luan S,
#=GF RA   Li L;
#=GF RL   Cell Res. 2014;24:632-635.
#=GF DR   INTERPRO; IPR003864;
#=GF DR   TC; 1.A.17;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   RSN1_7TM is the seven transmembrane domain region of putative
#=GF CC   phosphate transporter [1,2]. The family is the 7TM region of
#=GF CC   osmosensitive calcium-permeable cation channels [3].
#=GF SQ   76
#=GS Q2H2M5_CHAGB/395-667      AC Q2H2M5.1
#=GS V5INW6_NEUCR/401-673      AC V5INW6.1
#=GS A1C5G9_ASPCL/421-694      AC A1C5G9.1
#=GS Q2H842_CHAGB/486-758      AC Q2H842.1
#=GS Q7RWN3_NEUCR/522-795      AC Q7RWN3.1
#=GS YA7D_SCHPO/374-647        AC Q09766.1
#=GS Q6CTP0_KLULA/391-664      AC Q6CTP0.1
#=GS PHM7_YEAST/383-656        AC Q12252.1
#=GS Q6FQA3_CANGA/385-658      AC Q6FQA3.1
#=GS Q757I3_ASHGO/385-658      AC Q757I3.1
#=GS Q6C266_YARLI/385-657      AC Q6C266.1
#=GS Q6BLR7_DEBHA/372-645      AC Q6BLR7.2
#=GS Q756H9_ASHGO/391-665      AC Q756H9.2
#=GS Q6CNN9_KLULA/380-653      AC Q6CNN9.1
#=GS RSN1_YEAST/387-660        AC Q03516.1
#=GS Q6FSA1_CANGA/369-642      AC Q6FSA1.1
#=GS Q0V4S6_PHANO/390-663      AC Q0V4S6.2
#=GS Q5K752_CRYNJ/428-703      AC Q5K752.1
#=GS Q5KMP4_CRYNJ/459-736      AC Q5KMP4.1
#=GS Q8SV30_ENCCU/487-763      AC Q8SV30.1
#=GS Q16T32_AEDAE/383-653      AC Q16T32.1
#=GS F1MY22_BOVIN/433-705      AC F1MY22.1
#=GS A0JP96_XENTR/418-691      AC A0JP96.1
#=GS CSC1_MOUSE/407-680        AC Q8CBX0.1
#=GS CSCL1_HUMAN/421-693       AC O94886.3
#=GS Q54RR3_DICDI/412-689      AC Q54RR3.1
#=GS Q75JR4_DICDI/382-655      AC Q75JR4.1
#=GS Q75JX3_DICDI/461-732      AC Q75JX3.1
#=GS Q6ZLQ0_ORYSJ/372-643      AC Q6ZLQ0.1
#=GS CSCLD_ARATH/362-634       AC Q9C8G5.1
#=GS CSCLD_ARATH/362-634       DR PDB; 5Z1F A; 362-635;
#=GS CSCLD_ARATH/362-634       DR PDB; 5Z1F B; 362-635;
#=GS Q6AU79_ORYSJ/371-643      AC Q6AU79.1
#=GS CSCL1_ARATH/373-645       AC Q9FVQ5.1
#=GS Q5JLH8_ORYSJ/370-642      AC Q5JLH8.1
#=GS CSC1_ARATH/374-646        AC Q5XEZ5.1
#=GS CSC1_ARATH/374-646        DR PDB; 6IJZ A; 374-646;
#=GS CSC1_ARATH/374-646        DR PDB; 6MGW A; 374-646;
#=GS CSC1_ARATH/374-646        DR PDB; 6MGV B; 374-646;
#=GS CSC1_ARATH/374-646        DR PDB; 6MGV A; 374-646;
#=GS CSC1_ARATH/374-646        DR PDB; 6IJZ B; 374-646;
#=GS CSC1_ARATH/374-646        DR PDB; 6MGW B; 374-646;
#=GS CSCL2_ARATH/371-643       AC Q9SY14.1
#=GS B3H4A0_ARATH/254-522      AC B3H4A0.1
#=GS Q5JKX1_ORYSJ/351-617      AC Q5JKX1.1
#=GS Q2QLP9_ORYSJ/355-621      AC Q2QLP9.1
#=GS Q75GI5_ORYSJ/355-621      AC Q75GI5.1
#=GS CSCLB_ARATH/349-615       AC F4I248.1
#=GS Q2QN15_ORYSJ/341-606      AC Q2QN15.1
#=GS Q5KJ52_CRYNJ/418-692      AC Q5KJ52.2
#=GS CSC1_SCHPO/439-708        AC Q09809.2
#=GS A0A1D8PDS7_CANAL/411-689  AC A0A1D8PDS7.1
#=GS Q6BHX0_DEBHA/398-676      AC Q6BHX0.2
#=GS Q6C0S9_YARLI/463-736      AC Q6C0S9.1
#=GS Q6CQA3_KLULA/432-702      AC Q6CQA3.1
#=GS Q5ANH1_CANAL/480-746      AC Q5ANH1.1
#=GS Q6BI49_DEBHA/468-734      AC Q6BI49.2
#=GS W1QAI2_OGAPD/391-660      AC W1QAI2.1
#=GS Q2HEX8_CHAGB/435-711      AC Q2HEX8.1
#=GS Q7SFU1_NEUCR/440-716      AC Q7SFU1.1
#=GS A1CS74_ASPCL/432-711      AC A1CS74.1
#=GS C8VTT7_EMENI/430-709      AC C8VTT7.1
#=GS Q5KMP2_CRYNJ/545-829      AC Q5KMP2.2
#=GS Q5K800_CRYNJ/414-700      AC Q5K800.2
#=GS A0A0D1DVU1_USTMA/390-676  AC A0A0D1DVU1.1
#=GS YGV8_SCHPO/369-656        AC O43022.1
#=GS G4ULP2_NEUT9/388-671      AC G4ULP2.1
#=GS Q2GZW7_CHAGB/386-670      AC Q2GZW7.1
#=GS Q0CNN2_ASPTN/381-664      AC Q0CNN2.1
#=GS Q5B9A0_EMENI/380-664      AC Q5B9A0.1
#=GS Q0UJ62_PHANO/374-659      AC Q0UJ62.2
#=GS Q0V7D2_PHANO/304-586      AC Q0V7D2.2
#=GS Q6CA07_YARLI/396-669      AC Q6CA07.1
#=GS Q59TM5_CANAL/442-717      AC Q59TM5.1
#=GS Q6BHN0_DEBHA/458-733      AC Q6BHN0.2
#=GS Q6CJU8_KLULA/541-816      AC Q6CJU8.1
#=GS Q75FA6_ASHGO/578-853      AC Q75FA6.1
#=GS SPO75_YEAST/473-748       AC Q07798.1
#=GS Q6FVT6_CANGA/490-765      AC Q6FVT6.1
#=GS Q0UCF6_PHANO/681-953      AC Q0UCF6.2
#=GS Q2TX45_ASPOR/350-610      AC Q2TX45.1
#=GS A1CSW7_ASPCL/666-938      AC A1CSW7.1
#=GS Q7SA72_NEUCR/767-1042     AC Q7SA72.1
#=GS Q0UR74_PHANO/392-666      AC Q0UR74.1
Q2H2M5_CHAGB/395-667                 RRYAVLGFIAAMILFWAIPVAFV.GIVSNIDFLSS.ISFLRWL...NE.IPDVIM.GVVTGLLPSVLLSILMSLVPIVMRLCAKLAGEPSVSRVELFTQNAYFAFQVIQVFLVATLSSSATAV............AEQIVN.............NPTSAPSILASNL..P......KASNLYISYFIVQGLTIATSVLTQVVGFFIFSLLYKFLA......NTPRALYQKWSNLSAISWGSTLPVYTNIVVIAITYS...CIAP..LMLGWATVAMFLFYFAWRYNIFFVTD.TQI.DTR...GLIY..PKAIKQLFTGIYLAEVCMIGLF
V5INW6_NEUCR/401-673                 RRYAVYAFITAMIIFWAIPVGVV.GIISNVNYLKT.ISFLTWL...DD.IPGFIL.GAVTGLLPSIALSILMSLVPIVIRICAKLSGEPSLSRVELFTQHAYFAFQVIQVFLVATVASSATAV............AKQIAD.............NPGSVTKLLSENL..P......KSSNFYISYFIVQGLSIATSVLTQVVGFFVFNLVYKFLA......NTPRALYTKWANLSAISWGSTMPVYTNIVVIAIAYA...TIAP..LMLGWATVAMGLFYLAWRYNVLFVTD.TQI.DTR...GLIY..PRAIKQLYTGIYLAEICMIGLF
A1C5G9_ASPCL/421-694                 RKFAIKGGIAALIIFWSIPSAAV.GTISNITYLTHLIPILGFI...DK.LPDTLK.GVIAGLLPSAALVLLMSLVPIICRFCARRAGSPSTAHVELFTQSAHFCFQVVQVFLVTTLTSAASAA............TAQIIK.............DPLSAKDLLAENL..P......KATNFYISYFLLQGLTMSSMAVVQVAGMIVFKFMSTFFD......RSPRHLYQRWASLSGISWGNVFPVFTNMGVIALTYA...CIAP..LILGFAFIGLFLVYQAYRYNFLFVYD.IQT.DTK...GLVY..PRALQHLLTGIYLAAICMIGLF
Q2H842_CHAGB/486-758                 RRFFMMGVIAVAIVFWSIPAALA.GMVTNIKSLSETIFFLEWV...ML.LPGPIL.GVIQGLLPALALSWLMAAVPWMLRGCARVAGVPSRALVELYVQHAYFFFQVVQVFLVTTLTSAASAA............VFDIIQ.............NPLMVKDMLSENL..P......KASNFYLSYILIQCLAAGTTRLANVGDLIRHEVIAKTL.......PNPRRRFYRWRKMREVHWGSEFPRFTNLGVIAISYS...CIAP..MVLVFAGLGMFFTSYIYRYNLIYVYD.TGP.DSK...GLFY..PRALMQLMTGLYIAEICLIGLF
Q7RWN3_NEUCR/522-795                 RQFLMLALVVVAIIFWSIPSAAV.GIISNIDFLSEKVPFLFWI.....PLLPKVILGVIKGLLPAVALSMLMAIVPAGLRVCARVAGCPSHALVELYCQSAYFAFQVIQVFLVTTITSAASAA............IIDVIK.............QPMSAPNLLAQNL..P......KASNFYLSYILVQCLGAGAGKLANVSDLLRHYVATSFM.......VDPRKAYHRWRKLTPIHWGAVYPRFTNMGVIALAYS...CISP..LILVFAGFGMLFVGLVYRYNLIYIHDDSEL.DTK...GLLY..PRALLHLMVGLYIAEICLIGLF
YA7D_SCHPO/374-647                   KKTISNTILTLMIIFWAFPVAVV.GCISNVNYLIEKVHFLKFI...DH.MPPKLL.GIITGILPSVALSILMSLVPPFIKFLGKFGGALTVQEIENYCQNWYYAFQVVQVFLVTTMTSAATSA............VVQVIK.............EPASSMTLLASNL..P......KASNFYISYFLLQGLSIPGGALLQIVTLLLSKVLGRIFD......NTPRKKWNRWNQLSAPSWGTVYPVYSLLVTIMICYS...IIAP..IIIGFAAVAFVLIYFAYSYNLIYVLG.HNA.DAK...GRNY..PRALFQVFVGLYLAEVCLIGLF
Q6CTP0_KLULA/391-664                 KRLGGNTILTLMIIFWAIPVAVV.GCISNINFLTDKVPFLRFI...DN.MPDVLM.GVITGLLPTILLALLMSLVPVFIKKVAMMTGALTRQEIELYCHAWYYAFQVVQVFIVVTLASSASST............VTDIID.............EPDSAMTLLAQNL..P......KASNFYIAYFLLQGLTVPSGALLQVVALILSKVLGRVLD......KTPRQKWARYNTLSQPSWGVVYPVLELLVCIFITYS...IIAP..IILVFSTVALGFFFLAYLYNLTYVMS.FSY.DLR...GRNY..PRALFQVFVGLYLAEICLIGLF
PHM7_YEAST/383-656                   RRAVANTIMVLLIIFWAFPVAVV.GIISNVNFLTDKVPFLRFI...NN.MPTFLM.GVITGLLPTIALVVLMSLVPPFIVMLGKLSGCVTRQETDLYSQAWYYAFAVIQIFLVVTATSSASST............VDSIID.............RPRSAMTLLANNL..P......KASNFYIMYFILKGLTGPTWTILQAVNLLLSKVLGRVLD......STPRQKWNRYNTLATPRMGIVYPGIEILVCIYICYS...IIAP..ILLFFSTVMLTLLYVAYLYNLNYVFG.FSF.DLK...GRNY..PRALFQIFVGIYLSEVCLLGLF
Q6FQA3_CANGA/385-658                 KRLTANSILTAMIIFWAIPVAVV.GCISNVNFLVEKIHFLHFL...NN.VPNVIM.GIITGLVPSLALSILMSLVAPFIKKIGEMSGDITRQETDQYCQKWYFAFQVLNTFIVTTLASSASST............VTAIID.............EPGSAMTLLANNL..P......KASNFFITYFLLQGLTMPTGQLLQVANLILSKFMGRILD......TTPRQKWNRYNTLSKPSMGVVYPTVEILVCIMISYI...IIAP..ILLVFSTMTFLFLYFAYLYNLNFVMG.FSF.DLK...GRNY..PRALFQVFVGIYLSQVCLLGLF
Q757I3_ASHGO/385-658                 KRLVGNSILTAMIIFWAIPVAVV.GCISNINFLTEKVHFLRFI...NN.LPDVLM.GLITSLLPTIMLAVLMSLVPIFIQLVANKTGSISRQETQLYCQRWFYAFQVVHVVLVVMLASSAAST............VTAIID.............DPNNAFEQLAQNM..P......LSANFYLSYVMLFAFIFASGVLLQLTGFVLSFILGRILD......STPRQKWTRYNTLNLPTWGVMYPLMELQVCIMLAYA...IVTP..VLLIISTLALLFAYVAYMYVFNYVYG.LKH.DYK...GRNY..VNALFQVFVGLYLAEVFLFALF
Q6C266_YARLI/385-657                 KAMVVKAFLTALIVLWAIPVAVV.GSFSNIKSLTGLVPFLDFL...NN.LPSQLQ.GLVSGLLPTILMAVLMMLLPIIIRQCAKQAGCPTTTRVEYYTQNAYFAFQFVNVFLITTFASSAAAT............VKAIKD.............NPGSVMTMLSGNL..P......KSSNFFVSYIMLQALSFPGGALLQIVALILFKLLGTLLD......NTPRKMWTRYNILGSTSWGTVFPMYTFLIVVSIAYA...CVSP..IILVFSAVGFALIYLVFLNNLVYCEVPA...DGR...GIYY..SRALRQTMLGIYFGQIFMLALF
Q6BLR7_DEBHA/372-645                 RRLFACADVVLLIIFWAVPVALV.GVISNITYITKVLPWLDWI...NN.MPDQLL.GIITGLLPTAMLSLLNTFLPIFIRYMAKVAGCPTLQSIEFYTQDAYFAYLMVNAFLVVALASSAVSV............VEKIID.............NPTSAMKILATNL..P......KSSNFFISYIALQGLTVSSGALLQIVGLFLYYILGALLD......STVRKKWNRFSGLGTMLWGTTFPVYTNLACIVLAYS...IIAP..MILIFACIAFFLLYIAYCYNLTYVFV.ESP.DSR...GMHY..PRALMQTFVGLYLGQVCLLGIF
Q756H9_ASHGO/391-665                 AKLIAGVSITGVIVLWAIPVGAI.GIFPQKIRSAKSDPNNKWG...RL.VPPEPMDGILISLLPTILLYVLMMLLPIFIRRMAIFAGAPSVQHVEYYTQRAFFAFQLIQIFLIRTVSSVAYVL............IKELIN.............NPTAIMNELALKV..P......QASNFYLGYIVTILLSLSSSLLLQLAPLVLFYVMGLLFD......STVRKQYMRFITLPTPEWGTTFAVYTNLAVIVMAFS...ITSP..LILPLAAVGFFAAYVGYLYSLIYVYK.ESP.DAR...GIHY..PRALFQTLTGVYISQIFLFLMV
Q6CNN9_KLULA/380-653                 RKFGSIAAIVALVILWAFPVAFV.GMVSNITYLTNKLPWLKFI...YN.MPDQLL.GIITSLAPTIALAVLMMLLPIFIRKMALIAGAPSYQHVEYFTQQAYFAFQVIQVFLVTTLASSATST............VTAIVE.............EPTSAMNLLAENL..P......KSSNFYVGYIILQGLSISSGALLQIVPLILFFVLGMFLD......STARKKYARFTSLSSMAWGTTFPVYTNLAVITFSYA...IISP..LILLFACVAFFLLYVAYLYNLTYVFQ.ESP.DSR...GIHY..PRALFQTMVGLYLGQICLLGLF
RSN1_YEAST/387-660                   REVSAVSAIVALVILWAFPVAFV.GMISNITSLTNEVKWLKFI...YK.LPKQLL.GLLTSLAPTVALAVLMSFLPKFIRGMAITQGAPSKQNVEYFTQQAYFAFQVIQVFLVTTLSSAATST............VTEIVK.............EPTKAMDLLASNL..P......KASNFFMSYVILQGLSISSGALLQIVPLILFYVLGAFLD......GTVRKKWNRFCGLSSMQWGTAFPVYTNLAVITFSYS...IISP..LILLFAAVAFFLLYIAYLYNLTYVYQ.ESP.DAR...GIYY..PRALFQTIVGIYIGQICLLGLF
Q6FSA1_CANGA/369-642                 RELGSVGAIIALVILWAIPVAFV.GMISNITYLTNKLHWLRFI...YH.LPDVLL.GLLTSLAPTVALSLLMMLLPMFIRGMAKIQGATSSQQVEYFTQQSYFAFQVIQVFLVTTITSAATST............VTQIVE.............EPTSAMRLLAENL..P......KASNFFIAYIILQGMSIASGSLLQISPLAMFYALGYLLD......KTPRKKWTRFTTLGSVDWGTTFPIYTNLAVIVFSYA...IISP..IILLFGACGFLLLYIAYLYNLTYVWQ.EAS.DAR...GVHY..PRAMYQTIVGLYIGQICLLGLF
Q0V4S6_PHANO/390-663                 QEGIALALVIATIIFWSIPVSLV.GAVSNIGYLAENFKWLAFL...NK.LPPTAI.SLLSGLLPPLLLSMLASYVPKIFRYIFKTFGEATNTSAELRVVKWYFVFQVLQVFLVTTLASGAAAV............VSQIAN.............NPTSIPQLLADKL..P......SASNTYLTYFIIQGLSNAPSNVLNYSDVLSWAFFDKFFD......KTPRQKYNSYVYMRGMQWGKLFPKYVNFVIIAIAYA...CIAP..LVLGFAALGLGLFYYSYRYQLLYTNQ.PKV.DTK...GHCY..TLALQQILTGIYIAELCLFGLF
Q5K752_CRYNJ/428-703                 RTIVSWCLTVGLIIVWAIPVAFV.GMISNVDTLCANASWLAWI...CE.LPPAAL.GIIKGVLPPALLAVLFMLLPVVLRLMVKMQGEIRKSDIELKLFSRFWLFQVIHGFLIVTLASGLINA............LGNLGD.............TAGEVPTLLATKL..P......GASIFFLTFILTATLSGAAKTYARLVPWIMYLLRDILAG......GTPRKVYLKKYKMDSFTWSTAFPPTCLIICVTIVYS...VIQP..IITVLALVAFILLYCANKYVIHWCADQPDAAETG...GLYY..IKALRTVFVSLYIQGVCMAGLF
Q5KMP4_CRYNJ/459-736                 RQAISWAATFGLILLWATPVAFI.GALSNVTTLTEKYHWLAWIN.GTS.FGKKVLQGVISGILPPVLLALLMELVPFILRQLAAFEGFPSRTEVEINLMTRYFLFLVIHTFFIVTLASGLISS............IQQFAD.............NPGSAATTLATQM..P......TASTFFITLILTQ.FTGTMGSLLRVVNLLLYYVRIILLG......GSPRSVFTSRYRLNRPQFGETFPKITVYVVIMIAYC...VISP..IINGFSAAFFVFATLVYKYLYIWVIDQPPSQDTG...GMFF..PKAITHVFVGLYVQEVCMAAMF
Q8SV30_ENCCU/487-763                 YSIFGTVFFILFIVLFSSMVTSIVTLLVNFEGFKESKLISSFL......SRYETIADSLRGALSPLIYNSMLLLVPTVITALMNMEGIYSYSTLQQKLMDKLCNFLFFNGFASVFFVTSFYRL............FSDVLS.............RNKEIYDIVEAFSKES.....LESSVFFANIIIQKSLVGTALTLLKPAPLLINYIIFPFTG.....RKTRREKLDAEFSPP.FDFGTIFPSCLTVFSMSIAYA...VMCP..PILLLGAFFYFCNYLAFKSEFLYSSR.NEY.ESG...GGYW..DSACQNIVFSLIFFQVVTFAKM
Q16T32_AEDAE/383-653                 KWIAVNLVLFLFLFFLTTPVIIV.NQLDTLSLTKNTTSQISKI............SPLISEFLPTLLLWSMSALMPVIVAYSDTWLSHWTRSRQNYVIMTKTFGYLLFMILILPSLGLTSAEAF.........LQWTIHYN................ETYRWECIFL..P......DKGAFFVNYIITAAFIGTALELIRFPDLICYIWKLATSK......SRAETPYIRKSILITFPFGIHYAWMVMVFTMSTVYS...LACP..LIMPFAMVYIMLKHFVDKHNLFFAFAPSNM.ISQGSGGKIH..STAVTMTKVSVVLLLSIMAALA
F1MY22_BOVIN/433-705                 RCLVINVVLFILLFFLTTPAIII.TTMDKFNVTKPVEYLNNPI...............ITQFFPTLLLWCFSALLPTIVYYSAFFEAHWTRSGENRTTMHKCYTFLLFMVLLLPSLGLSSLDLF.........FRWLFDKK............FLAEAAIRFECVFL..P......DNGAFFVNYVIASAFIGNAMDLLRIPGLLMYMIRLCLAR......SAAERRNVKRHQAYEFQFGAAYAWMMCVFTVVMTYS...ITCP..IIVPFGLMYMLLKHLVDRYNLYYAYLPAKL.DKKIHSGAVNQVVAAPILCLFWLLFFSTMRTGF.
A0JP96_XENTR/418-691                 RFLALNLLLFVLLFFLTTPAVIV.STMDRFNVTYPVEKLRNPV...............ITQFLPTFLLWMFSVCLPFLVYYSAFFECHWTRSSENQHTMHKCYFFLVFMVIVLPSLGLTSLNLF.........FRWLFDIH............FLDEANIKFQCVFL..P......NNGAFFVNYVITASLIGTAMELLRFPGLTVYAARLCLAR......TEPDRLHVKRNQAYEFQFGLEYAWTTCVFSVVMAYS...ITCP..VIVPFGLIYMLLKHMTDRYNIYYAYIPTKL.SPGLHKAAAYQMLAAPVLCIFWLLFFSVLRLGST
CSC1_MOUSE/407-680                   RFIAINTFLFFLFFFLTTPAIII.NTIDIYNVTRPIEKLQSPI...............VTQFFPSVLLWAFTVTMPLLVYLSAFLEAHWTRSSQNLIIVHKCYIFLVFMVVILPSMGLTSLHVF.........LRWLFDIY............YLEHATIRFQCVFL..P......DNGAFFINYVITAALLGTGMELMRLGSLC.TYCTRLFLS.....KSEPERVHIRKNQATDFQFGREYAWMLNVFSVVMAYS...ITCP..IIVPFGLLYLCMKHITDRYNMYYSYAPTKL.NAQIHMAAVYQAIFAPLLGLFWMLFFSILRVGSL
CSCL1_HUMAN/421-693                  QWLGINFTLFLGLFFLTTPSIIL.STMDKFNVTKPIHALNNPI...............ISQFFPTLLLWSFSALLPSIVYYSTLLESHWTKSGENQIMMTKVYIFLIFMVLILPSLGLTSLDFF.........FRWLFDKT.............SSEASIRLECVFL..P......DQGAFFVNYVIASAFIGNGMELLRLPGLILYTFRMIMAK......TAADRRNVKQNQAFQYEFGAMYAWMLCVFTVIVAYS...ITCP..IIAPFGLIYILLKHMVDRHNLYFVYLPAKL.EKGIHFAAVNQALAAPILCLFWLYFFSFLRLGMK
Q54RR3_DICDI/412-689                 RRIVSSIIFFVIFCFYTIPVTAI.SAVSNIQTLSK.VPVLNWLL.EVV.NLDDTLRGFVEGYLPSLALVLFLALLPLFIKIIIHFNKEDTRTQFYHKVFTVYWAFLVTNVFLVVSIAGTVLGIL.........FKMLENLT..............LKDIATLLGQSL..P......KQSSFFINYILVQALTSVPMDIVRPIELIAGIIRSSRES......SFGQKMKALSHDDPTSLNSIKYARELLIFVITLSYS...TLSP..LILPFGLLYFLMDFFVSKYNHIYSFC.PKY.QSG...GMIW..PLVFNRLCIGLVIYQLTGIGLF
Q75JR4_DICDI/382-655                 RSLIVAILTFALVFLWGIPVAFL.SGFSNLETISRV.KAFSWITDIIS.KSKILQ.GFLSGFLPNLILIIFMILLIPIIYALSRACGYFSNSRIEASVFSKYFLFLVFNVFLVSAIAGTIFQS............IEQIAN.............DPTSIIGSIANSL..G......GLSFQMINYILIAAA.GSFGAILRIVGLIIQLIKLKWLA......KTKRQIDDTL.HQGPFAYGVNYAKNLLILQLTLAYS...TLSP..FILIFGAWYFGLSYLVQKYNIIWVNT.PNY.QCG...GFMS..PMHFRRTIIGLLIYHILMIGTF
Q75JX3_DICDI/461-732                 RGLIIMVLTFLLIFFYTIPITFI.SGFSNLGTLAKIKAFSWLFT.LIN.KSPTLT.SFLTGFLPGLALMIFLALLVPILTMFSRFSGYYSKSAIEASIFSKYFLFLVFNVFLVSAIAGTIFQS............ISAIID.............NPPSITTTLANSL..G......GLSYAMINYVLLAA.TSLTMNLLRISDLLVDQFKLKFI......CKTKRDIEDTE.STDPFKYGQLYAYNLLVLQLCFAYS...TLSP..FILVFGVWYFGVSYLVHKYNIIWVNKPHIT.......QLLY..PMSFRRTMIALLIYHLLMIGTF
Q6ZLQ0_ORYSJ/372-643                 RQVVVYTIVFLTVVFYMIPITAI.SALTTLEKLREKLPFLKVV......VDQPKIKTVLQAYLPQLALIVFLALLPSLLMFLSKLEGIPSQGHTVRAAAGKYFYFIVFNVFLGVTISSTLFSA............LTTIIN.............NPPGIVNMLASSL..P......GSATFFLTFVALKFFVGYGLELSRLVPLIIFHLKRKYLC......KTEDEVRAAW.APGDLGYNTRVPNDMLIVTIVLCYS...VIAP..LIIPFGVAYFALGWIIVKNQVLRVYV.PSY.ESN...GRMW..PHMHTRIIAALLIYQITMVGVI
CSCLD_ARATH/362-634                  RQYFIYFFVAVTILFYMIPIAFV.SAITTLKNLQRIIPFIKPV....V.EITAIR.TVLESFLPQIALIVFLAMLPKLLLFLSKAEGIPSQSHAIRAASGKYFYFSVFNVFIGVTLAGTLFNT............VKDIAKN...........PKLDMIINLLATSL..P......KSATFFLTYVALKFFIGYGLELSRIIPLIIFHLKKKYLC......KTEAEVKEAW.YPGDLSYATRVPGDMLILTITFCYS...VIAP..LILIFGITYFGLGWLVLRNQALKVYV.PSY.ESY...GRMW..PHIHQRILAALFLFQVVMFGY.
#=GR CSCLD_ARATH/362-634       SS    HHHHHHHHHHHHHHHSHHHHHHH.HTT----------------....-.------.TTHHHHHHHHHHHHHHTTHHHHHHHHHTTS--SBHHHHHHHHHHHHHHHHHHTTTHHHHHHHHHS--............-------...........----HHHHHHHHHH..H......HHHHHHHHHHHHHHHHHHHHHHHTHHHHHHHHHHHHHTT......TTT-TTS---.------HHHHHHHHHHHHHHHHHHH...HH-T..HHHHHHHHHHHHHHHHHHHHHTTS--.-S-.--S...STHH..HHHHHHHHHHHHHHHHHHHHH.
Q6AU79_ORYSJ/371-643                 RRLIMAVALFFLTFFFMIPIAIV.QSMANLDDIERMLPFLKPI......IERNSLKSIVQGFLPGIALKIFLILLPTFLVMMSKIEGHTSLSGLDRRTASKYYLFLFVNVFLGSVITGTAFQQ............LNNFIH............QSANKIPEIVGESI..P......MKATFFITYVMVDGWAGVAAEVLRLKPLVMFHIKNTFLV......RTERDREQAM.DPGSLDFGTTEPRIQLYFLLGLVYA...VVTP..ILLPFIIVFFSLAYLVFRHQIINVYN.QQY.ESG...AQFW..PDVQRRLVIALIVSQILLLGLL
CSCL1_ARATH/373-645                  RKLVIGVSVFALVFFYMIPIAFV.QSLANLEGLDRVAPFLRPV......TRLDFIKSFLQGFLPGLALKIFLWILPTVLLIMSKIEGYIALSTLERRAAAKYYYFMLVNVFLGSIIAGTAFEQ............LHSFLH............QSPSQIPRTIGVSI..P......MKATFFITYIMVDGWAGIAGEILRLKPLVIFHLKNMFIV......KTEEDRVRAM.DPGFVDFKETIPSLQLYFLLGIVYT...AVTP..ILLPFILIFFAFAYLVYRHQIINVYN.QQY.ESC...GAFW..PHVHGRIIASLLISQLLLMGLL
Q5JLH8_ORYSJ/370-642                 RRLIIAVAFFFLNFFYVLPIAFV.QSLANIEGIEKAAPFLKPL......IEMRTIKSFIQGFLPGIALKIFLILLPSILMFMSKVEGLTSVSSLERRSAFKYYIFLFFNVFLGSIIAGSALEQ............LKTFLH............QSANEIPRTIGEAI..P......MKATFFITYVMVDGWAGVAGEILRLKPLIIFHLKNFFLV......KTEKDREEAM.DPGSIGFDSNEPQIQLYFLLGLVYA...VVTP..FLLPFILIFFGLAYVVYRHQIINVYN.QEY.ESA...AAFW..PSVHGRIIVALIVSQLLLLGLL
CSC1_ARATH/374-646                   RRLIMHVAFFFLTFFFIVPIAFV.QSLATIEGIVKAAPFLKFI......VDDKFMKSVIQGFLPGIALKLFLAFLPSILMIMSKFEGFTSISSLERRAAFRYYIFNLVNVFLASVIAGAAFEQ............LNSFLN............QSANQIPKTIGVAI..P......MKATFFITYIMVDGWAGVAGEILMLKPLIMFHLKNAFLV......KTDKDREEAM.DPGSIGFNTGEPRIQLYFLLGLVYA...PVTP..MLLPFILVFFALAYIVYRHQIINVYN.QEY.ESA...AAFW..PDVHGRVIAALVISQLLLMGLL
#=GR CSC1_ARATH/374-646        SS    HHHHHHHHHHHHHHTTHHHHHHH.HHHH-SHHHHTTS---SSS......---SSHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHS---BHHHHHHHHHHHHHHHHHHHTTHHHHHHHHHHHT............HHHHHH............STTSSHHHTHHHHH..H......HTHHHHHHHHHHHTHHHHHHHTT-HHHHHHHHHHHHHT-......-STTTHHHHG.-S-S--HHHHHHHHHHHHHHHHHHT...TT-G..GGHHHHHHHHHHHHHHHHHHHHHS--.-S-.--S...STTH..HHHHHHHHHHHHHHHHHHHHHT
CSCL2_ARATH/371-643                  RRLLTTVALFFLIFCFMIPIAFV.QSLANLEGIQKVLPFLKPV......IEMKTVKSVIQGFLPGIALKIFLIILPTILMTMSQIEGYTSLSYLDRRSAEKYFWFIIVNVFLGSIITGTAFQQ............LKSFLE............QPPTEIPKTVGVSI..P......MKATFFITYIMVDGWAGIAAEILRVVPLVIFHLKNTFLV......KTEQDRQQAM.DPGHLDFATSEPRIQFYFLLGLVYA...AVAP..ILLPFIIVFFAFAYVVFRHQVINVYD.QKY.ESG...ARYW..PDVHRRLIICLIISQLLMMGLL
B3H4A0_ARATH/254-522                 NKIGVILAAALLTIFFAIPVTAV.QGIAKYEKLKKWFPPAMAI....E.FIPGLS.SVVTGYLPSAILKGFMYIIPFAMLGLAYLGGSISNSKEEIKACNMVFYFLMGNVFFLSLISGSLLDE............IGEYLT.............HPRDIPSHLAAAV..S......AQAEFFMTYILTDGLSGFSLEILQLGLILFDIIRSYTYG..........RGKERTPYLFSFPYFRVIPTVSLSIMIGMIYA...VVAP..LMLPFLVGYFCLGYIVYFNQMEDVYE.TTY.DTC...GRFW..PFIHHYIFVSIILMQITMVGLF
Q5JKX1_ORYSJ/351-617                 YKLGVFIAAFLLIVFFTIPVTAV.QGIVQFEKIKIWFPPARAV.....ELIPGLN.SVVTGYLPSMILNGFIYLIPFAMLGMASFEGCIAKSQKEIKACNMVFYFLLGNVFFLSILSGSLLHQ............IGESFT.............HPKDIPSRLARAV..S......AQSDFFITYILTDGMSGFSLEVLQFGLLTWHFFKAHSIG......HSEQPY......LYGFPYYRVVPIVSLAVLIGLVYA...VVAP..LLLPILVIYFLLGYAVYINQMEDVYE.ITY.DTC...GQYW..PNIHRYIFLSVTLMQITMLKSK
Q2QLP9_ORYSJ/355-621                 RRIATLLGSIVFMLFFLIPVTFI.QGLSQLEQLQQRLPFLKGI......LEKKYMSQLVTGYLPSVILQIFLYAVAPIMILFSTLEGPISHSERKRSACCKVLYFTVWNIFFGNVLSGTVISQ.............LNVLS.............SPKDIPVQLARAI..P......VQATFFITYVLTSGWASLSSELMQLFGLIWNFVRKYILR.....MPEDTEF......VPSFPYHTEVPKVLLFGLLGFTCS...VLAP..LILPFLLVYFFLGYIVYRNQLLNVYR.TRY.DTG...GLYW..PIAHNAVIFSLVLTQIICLGVF
Q75GI5_ORYSJ/355-621                 RKIATLAASVAFMFVFIVPVAFV.QSMMQLDQIEQLFPSLKNM......LKKPFFVKLVTGYLPSVVLLLSLYTVPPLMMFFSSIEGSISRSGRKKSACCKILFFTIWNVFFVNVLSGSVLNQ............LNVFTR..............PRDMPSMLAELV..P......KQATFFITYVLTSGWASLCSEILQVYNLVYNFFRKCIFC...........YRDDPEYGYSFPYHTEVPKVLLFNLLGFTFS...IMAP..LILPFLLVYFCLGYLVYRNQILNVYY.PKY.EMG...GKLW..PIMHSTLVFALVLTQTIALGVF
CSCLB_ARATH/349-615                  AKILVVFACLLLTILFLVPVVLV.QGLTNLPALEFMFPFLSLI......LSMKVVSQIITGYLPSLILQTSLKVVPPTMEFLSSIQGHICHSDIQKSACNKVIWFTIWNVFFATVFSGSAFYK............LSVILD..............PKQIPLKLAVAV..P......AQASFFIAYVVTTGWTDTLTELFRVVPFMVSYIKRSFEP......SDENEFV.....VPPMRYHRDTPRVLFFGLLGITYF...FLAP..LILPFILLYFILAYIIYRNQFMNVYA.PKF.DTG...GMFW..PMIHYTMIFSLVLMQAIAIGLF
Q2QN15_ORYSJ/341-606                 SKFVVSVASILLILVFLLVSAFV.QGLTYMEQLETWLPFLRNI......LEIAVVSQLVTGYLPSVILHFLSSYVPSIMKLFSTMQGFISVSGIERSACNKMLRFTIWSVFFANVLTGSVLGQ............LEIFLD..............PKEIPKRLAVVV..P......AQASFFITYVVTS.WTSIASELTQTAALLFHLWG...........SCAKCCKRDESKPPSMHYHSEIPRVLLFGLLGLTYF...IVSP..LILPFVLVYFCLGYFIYRNQLFNVYS.PKY.DTG...GRFW..PIVHGGTIFSLVLMHVIAIGVF
Q5KJ52_CRYNJ/418-692                 RDFIVMGIMGVLILTWIVPVSSL.ATLMSYEEIKKIMPWLARF...IG.SSPRLA.AIVQNSLPSLALITFNGLLPFLLEWLSYMQAFKSRSATEYSLMKKYHLFLLISVLLIFLLTSTYWAL............VRDLVD.............TPMKIPEKLARALQGS......NVRNFMVSYVMLQALGLMPLQLLNLGPLFSLALARAFWT......KTPRDYAEAN.APPMLNYGWVYPQALLVFTITLVYS...VMSP..LILIFGAIYFAMAYLVFKYKLLFIYF.KPY.ESN...GEAW..RITFARTLWALIIFQLFMTGLF
CSC1_SCHPO/439-708                   QGWFITLVTFMIILLWTVPVGAI.AVFINLDTIRRLWPELGRM...IE.DLPFLN.SLLRTFLPTLVYSLFISISPFLFRWLSSMQGLSSRAEEEIYAVGKNYAYLFVNFFLVYVIAGSTSIW..............ELAK.............DTTSFAHFLANRL..P......HQAQFFIDLIVLQGIGMFPLKLIQLGKLSSYFVRRSFVP.....YSIASKKFE...TPDSFSVGIFLPQPMFIMLICLCYS...IISP..LILVFGLIYFIIGFLVYKYELIYQME.HPQ.HST...GELW..STIFLRMIFGCVIMQLTMMGLM
A0A1D8PDS7_CANAL/411-689             KSYFITLVIVLSYGFIIFLVIPL.TSLLDLKTISKFWPALGEF...IG.QSKWLT.TFVTGILPPLLFTLLNFSFPYFYQYLSQLQGYTSNSDVELSTLSKNFFFIFFNLFLIYVAAGTFWDY............MSYISD..............TTKIAVQLATSL..R......RMALFYVDLILLQGLTMFPVKLLQVSDFFLLNVLGKLFYFKRLILKTPRDYRSYYFTPQIFDFGINLPQHILIFMIILIYS...VVST..KIVTCGLIYFILGLFVYKYQLVYNFV.HPP.HST...GKVW..PMIFRRVILGLIIFQLFMCGTL
Q6BHX0_DEBHA/398-676                 KSYVITFIVMLSCVILLFPVSSL.AALINVKTITKLWPALGKF...IA.KSKWLT.TFVTGILPPLLFSLLNISLPYFYRFLSQYQGYSSNSDIELSTLSKNFFYLFVNLFLVFTFAGTFSNY............WSFLSD..............TTKIAYQLASSL..K......SLSLFYVDLILLQGLAMFPVRLLQIGDVVILNVIGKIFLLKNIILKTPRDYRFYYYTPPMFDFGLQVPQHILIFIIILIYS...VVST..KIVTSGLIYFILGYLVYKYQLIYTCV.HPQ.HST...GKVW..TMIFRRLMLGLVLFQLFMCGTL
Q6C0S9_YARLI/463-736                 RTYAVTIAIGFLTVALVPPVLGV.AKLMDTKTISKSWPALGQL...LK.DTPWLE.KLVTGILPPYLFTILNFALPYFYVYLASLQGFISHGDEELSVISKNFFYIFVNLFLIFTVAGAAIDI............FQYLKD..............TTSIAYKLASSL..K......KWALFYVDLIVLQGIGMFPFRLLEFGNLLRFGFEKPIT.......HTPREFRSLY.TPPVFNFGLNLPQPILILIITLLYSVFDVMSS..KILAAGTAYFVLGYFTYKYLLMYAMV.HPS.HST...GQAW..PMIVRRVCVGLVLFHATMSGIL
Q6CQA3_KLULA/432-702                 KVYSVTVFIGICSVFLVIPVSYL.ATLLNLKTISKFWPGLGKF...LK.DNDWAQ.NLVTGLLPTYIFTLFNVVIPYFYEFLTKRQGMLSYSDEELSLVSKNFFYILVNLFLVFTLAGTASNY............WGYLSD..............TTKIAYQLSTSV..K......EFSLFYVDLIIFQGIGMFPFKLLLVGSLIGFPFVK..IQ.....CKTPRQRKELY.SPPVFNFGLQLPQSILIFIITLIYS...VMST..KILASGLAYFIIGYYVYKYQLIFAMD.HLP.HST...GKVW..PLVYRRVILGLLLFQLTMAGTL
Q5ANH1_CANAL/480-746                 KILAVTIFIGIMSLLLVYPVRFM.ASFLNTKSISKIWPSLGKA...IE.SHKWAE.TLITGLLPTYLFTILNIVIPFFYVWISEKQGYLSHSDEELSSVSKNFFYIFVNLFLVFTTFGTASFV...............................DTTKIAFDLARSL..R......DLSMFYVDLIILQGLGIFPFKLLLVGNLL.RFLVNSLFR.....CKTPRDYLNLY.KPPVFNFGLQLPQPILIFIITLVYS...VMSS..KILTAGLLYFIIGYFVSKYQLLYACV.HPP.HST...GKVW..PIIFRRIILGLFLFQITMVGTL
Q6BI49_DEBHA/468-734                 RIFFVTLFIGIFSLILVIPVRYL.AQFLSLKSISKVWPSLGKF...LE.SNRLAA.TLVTTLLPTYLFTILNIIMPYFYIWISSIQGYTSHSDEELSTVSKNFFYIFVNLFLVFTMAGTASLS...............................DTTEIAYQLAQSL..R......KLSLFYVDLIILQGLGIFPYKLLSLGNLFKFSIGALFWC......KTPRDYLNLY.KPPVFNFGLQLPQPILILIITIVYS...VMST..KILTAGLVYFIIGYFVYKYQLLYACV.HPP.HST...GKVW..PLVFRRIILGLLIFQLTMAGTL
W1QAI2_OGAPD/391-660                 KIYYITILTGILGVAFIFPVGYL.ATLLNLKTISKFWPDLGEL...LE.KHEWAQ.KFVTELLPVYLFTLLNFVIPYLYVWLSSRQGFVSHGEEELSVVSKNFFYVFVNLFLVFTMAGTASNY............WGYLSD..............SKKLALQLATSL..R......GLSSFYVDTILLQGLALMPFKLLITGHVLRFMFIRA.NC......KTPRDFKELY.RPPVFNFGLHLPHPILILIITLLYS...VMST..KILSSGLAYFIIGYFVYKYLLIYACI.HPQ.HST...GQVM..PIIFRRIVLGLLLFQLTVAGS.
Q2HEX8_CHAGB/435-711                 RSWTVTTFVAILSVVWLVPVAFL.ASVLSICTINKFLPAFGDW...LK.EHEIAR.TLVQTGLPTLVASLLNVAVPYLYDYLSWHQGMLSQGDIALSAISKNFFFTFFNIFLIFTIFGAVTSIF.........DVLRNSLK.............DTTYIAYTLARKI..E......ELSVFYTNFIMLQGLGLFPFRLLELGSIAQYLILR..MG.....AKTPRDFAELV.QPPKFYYGFYLPTALLVFILCLVYS...ALRGGSLVLGLGLAYFSLGYFTYKYQLLYAMD.QPQ.HAT...GGAW..RIICYRIVLGLVVFQLTMSGYF
Q7SFU1_NEUCR/440-716                 RSVAVTLFVAFLTVVWLVPVAFL.ASFLSICTIEAYFKGFAMW...LK.QYDLAR.ALVQTGLPTAVVSLLNVAVPYFYDYLSYQQGMLSRGDAALSTISKNFFFTFFNIFLIFTVFGAVTSII.........DVLRESLK.............DTTYIAYVLASKI..E......NLGVFYTNFIMLQGIGLFPFRLLQFGSVSLYPINR..LG.....AKTPRDFAQIV.SPPMFYYGFYLPTALLVFILCLVYS...ALPQGYKVVGLGVAYFTLGYFTYKYQLLYAME.QPA.HAT...GGAW..NMICYRIMLGLLVFQLTMSGYL
A1CS74_ASPCL/432-711                 QSWFITGVIGFLTVFWSVLLVPV.AYLLELETLHKVFPQLAEA...LA.RNPILS.SLVQTGLPTLVLSLLTVAVPYLYNWLSNQQGMMSRGDVELSVISKNFFFTFFNLFLVFTVFGTATTFY.........QFWETLRDA..........FKDATAIAFALAKSL..E......SFAPFYINLIMLQGLGLFPFRLLEFGSVAMYPIN..FLS.....AKTPRDYAELS.TPPTFSYGYSIPQTILILIICMVYS...VFPSSWLICLFGLVYFTIGKFIYKYQLLYAMD.HQQ.HST...GRAW..PMICSRVFVGLIVFQLAVIGVL
C8VTT7_EMENI/430-709                 QSWSITVLICFLSVFWSVLLVPV.GTLLKWETLHKVLPQLADA...LA.RHPLVK.SLVTTGLPTLAFSLLTVAVPYLYNWLSNHQGMMSRGDIELSVISKNFFFSFFNLFVIFTVIGTATNFY.........GLWEHLRDS..........FKDATTIATALANSL..E......NLAPFYMNVFVLQGLGLFPLKLLEVGSVFLYPINYLMA.......KTPRDYAELS.TTATFSYGYSIPQSILILVICVIYG...VFPASWLICFFGLVYFTIGNFIYKYQLLYAMD.HRQ.HST...GRAW..PMICNRVLVGLVVFQLAMAGTL
Q5KMP2_CRYNJ/545-829                 HAIIGKFALVIICFVNTIPLMIV.TVLANLGTAIDRWPTLAKLEDSSE.IWKAIF.TVLAGVLPATISAMFSYILPYIMRRLSRWSGALTRGQLDKAVIRQLFIFQLVSNFIVFSLLGVVYETYLTISEDIGKESWSTIYA.............GLGDVPAKVTQAY..I......SESLYWLSWYPIRSV.VACLQLLQIPRLILKTPQLLMI.......KTPHDLAEVA.QPENFEYAIEYSHVLFAMVVGLMYA...PLAP..IIVICAAIYFWALYIIHNNQLKFVFD.SK..ETD...GKCW..KILINRVLIATVFMQLFMVLTC
Q5K800_CRYNJ/414-700                 KNTFGFIIIGIVCFFNTLPLLVV.SLLANLSSLTVYVTFLADWKDAGS.WGQWTF.SMVSGILPSVVSALFGYLLPIIIRKISKYQGAPTRSRLDRAVTARYFFFMIISNLVIFSLLGVVYTA............IARIVVQVGGHQSVGTILKGFEDIPDQIQGTY..V......QQSTYWLTWLPLRGF.LVIFELIQLIKLAMVSIRRFMFS......HTPRDIREMT.KPPYFEYAIVIVNLLFITAVGLIYA...PLAP..LVAMGACCVFWFSSVVYKYQLLYVYI.SRA.ESG...GRMW..NVYVNRLLACCVLMQLLMVLT.
A0A0D1DVU1_USTMA/390-676             SSFFGFLMLLVLFFMNIFPLIIV.SLLSNMARLTS.ISWLRWLK.DWQ.TASSFTFAAVSGLGAPIIMGIASFFFPIAMRKIAKYRGVQTRYRLDRLLVGQYFGFLVISQFLFFSLIGVVLSLV.........SQLVVEINH...........DSALAIIKKLGRNAAYATKQQYLNQSNYWLTWLPLRGY.LAVFDLAQVIKLLLVWIQKVFLG......RTPRDVRE.YTKPPVFDYWIYYSNFLFMSAVAMIYA...PLAP..LVVVFSAIVFWASSFIYKYQLMYVFV.TKH.ETG...GMLW..RPTINRLLICIGFMQVILILAV
YGV8_SCHPO/369-656                   NRMIGNILFIILIIAWIIETALVAIFISNLYHLGSVWPWLQQQ...LT.SRSGFW.SIVQGILSPAVAGFTFMILEIIMRRISYWQGSFTKSSRERGVLNKLHIIFTLDNFIIYTLMAVFWRLG.........VIIAYKTKEEGNFAEGMSAFATFDTVGLSVSSFV.........QFSTFWIMFIAHSTCSFF.VEIAQPITLTIRLIKTKFFS......PTPRDLLE.WTAPTKYVYSQVLNKLIYFFTIAICYA...CINP..LVLLFASVLFCVNYLTQKYILMYVSN.SST.ESG...GGYW..RPVVNRILLGLELANIILFLCL
G4ULP2_NEUT9/388-671                 RRLWNNLWITVLTVVWVAPNAMIAIFLVNLSNLARVWPDFQKS...LE.TNRNFW.AIVQGIASPALTSLVYMVLPIIFRRLSMKAGDMTKTGRERHVVAKLYSFFVFNNLFVFSLFSALWSF............GATVIKNTATDD.DAWQAILDADFGTTVFVSL..C......GISPFWVVWLIQRQL.GAAIDLSQLWKLIYGSIMRKFTN......PTPRELIELT.APPPFDYASYYNYFLFYATAALCYA...PIMP..LVLPAAGMYFAIDVALKKYLLMYVFV.TKT.ESG...GMFW..RILFNRILFGLMLSHLIVFLV.
Q2GZW7_CHAGB/386-670                 RRLWNNLWMAVLTILWIAPNAMIAIFLVSLSNLGQVWQAFDVS...LK.ENPGIW.SIIQGIASPALMSLVYLVLPIIFRRLSIKAGDQTKTGRERHVVAKLYAFFVFNNLIVFSIFSALWTF...........TATVVQKTEKGI..DAWEAFVDADIGQTLFMSL..C......GVSPFWVTWLLQRQL.GAAIDLAQLWALLSSFFMRKFSS......PTPRELIE.LTAPPPFDYASYYNYFLFYSTVALCYS...AIQP..LVLPAAAMYFCIDVALKKYLLLYVFV.TKT.ESG...GMFW..RMLFNRFLFGSMLSHLVVFLIV
Q0CNN2_ASPTN/381-664                 KRFVNRIWVSILTVVWIAPNALIAIFLSNLNNLGLVWPAFQTS...LS.ASPNVW.AAVQGILSPAITSLFYLILPIIFRRLAIRAGDLTKTSRERHVLHHLYSFFVFNNLIVFSLFSAAWTF............VAAVVDAQRDE..NAWQAIKDGDFYQKIMSAL..C......QVSPFWVTYLLQRNL.GAAVDLVQLVNVFWVWFSKTFLS......PTPRQAIE.WTAPPPFDYASYYNYFLFYATVALCFA...TLQP..IVLPVTALYFGLDVMMKKYMLLYVFV.TKN.ESG...GQFW..RVLFNRMVFATILANVVIALIA
Q5B9A0_EMENI/380-664                 KAFVMFLWVTALTVVWIAPNALIAVFLSNLSNLGSVWPAFQTE...LD.RNRKVW.AAVQGILSPAVTSLFYLLLPIIFRRLSARTGDATKTLREQHVLRHLYSFFVFNNLIVFSLFSAVWTF............IAAVIDLKNKNEDPWQAVQDGQFYIKAFSAMC.........NVSPFWVTYLLQRNM.GAAIDLVQFVHLIWVWFAKTFLA......PTPRQTIE.WTAPPAFDYASYYNYFLYYSTIAICFA...TLQP..IVLPVTALYFGLDAMMKKYMLMYIFV.TKN.ESG...GQFW..RVLFNRVVFAAILSNVIIGLVA
Q0UJ62_PHANO/374-659                 RRFINHGWISLLTILYFIPNALIAIFLSKLPNLALVWEAFSVE...LN.RHPGFW.AVVQGILAPALTSLFYYFLPIIFRRLSMRAGDFTKTSRERHVTAQLYNFFVFNNLFVFSLFSAAFGM............ITLVVKYARDEHQPFMQIIREIQIFDTIMQTL..C......NVSPFWVTWLVQRNL.GAAIDLSQVANLAWGSFSRKFLN......PTPRELITRT.APPPFDYASYYNYFLFYSTVALCFA...PLQP..VTLVVVAFYFSIDSWMKKYLLMYVFC.TKN.ESG...GLYW..RILFNRMLVGVMLSNCIIALLC
Q0V7D2_PHANO/304-586                 RKFWDGLWIVLFTIAFIVPNILTSVFLSDFSHLGLVWPAFQQN...LL.AHPTGW.GIAQGILAPLVQTLMYMGVPVVFRRLFTHSGDVSRTSRERHVTARLYAFFVFNNLLVFSVFGSAWRF............VASVIAAQDRG...VWQAIQDGHLFSQLMTGL..C......NVSTFWLTWQMQRNL.GAAIDLSQAWIFTWSWIQRKCFS......PTPRELIELS.APQPFPYADYYNNYLFVSTVGLCMG...ILQP..IILPVTAFYLGMDCVFKKYLLQYVFI.TKT.ESG...GRFW..KVLVNRILFAVLLANAVIALIV
Q6CA07_YARLI/396-669                 RFAIATALNLALIIGWAIPVSVV.GLISQISYLTQLLPFLSFL...ND.LPEAIK.GAISGILPPLLLALLMMLVPPILTLLAYLKGISTGIRVQLDVQKYYYAFQYIQLFLVITVSSGLTTT............VQQIVD.............TPTSTPTILANNL..P......KAANFFMSYLILQGMITSMNNMLRVDELIFHLLARIMPA......TTAHRKFSRLSSISEVIWGNTFPTYTNLATIGIIYS...IISP..IILIFCLISFSLTYMAFKYRIIYCNV.NRV.NSY...GLFF..PTAIFQLFTGIYTLQLCLIGLF
Q59TM5_CANAL/442-717                 EKYLVTIAFISIIILYVIPVSLI.GLVSQIPLLTQLLPFLEWI...YQ.FPEEAR.ETIAGFLPSILLGVLTEIVMIIFRFLTYFKGRTTGCEVEIDLQKWYFAFLFVQQFLVVTISSSVTVI............LKQIID.............QPTSIPVLLATNL..P......KSATFFFQYISLRAFAFCGNNFLRISPLIQSLIVCKFID......ITPRQKFNRITNLPKIKWGTTFAVYSIYACIGISYS...IISP..LISIFIIFFLNLSILYYKYALKYVYSHINESETT...GRLY..PTALLHLYTGVYCLECCLIGVF
Q6BHN0_DEBHA/458-733                 EKYFVSLIFISVILLYVIPVSFI.GLVSQVPLLTKLIPSLKWI...YK.FPEEAR.DTISSILPSLLLAILTDIVLIVFRFLTYFKGMLSGADLELNLQQWYFAFLFVQQFLVVTISSSITVI............FKQIVD.............QPTSIPVLLATNL..P......KAATFFFQYITLKAFAFCGNNFLRIGPLMLHLTVHKIKD......KTPRQKFNRITNLLRIRWGSIYPVYSVFASIGICYC...VISP..LIAIFVIFILSLSLLYYKYALKYIYNRTNESDTK...GKHY..PIALLHLYTGIYCLECCLIGIF
Q6CJU8_KLULA/541-816                 RVAISNFLNVAIIIGWVVPVAIV.GFVSQIPIITKIVPILTNF...QD.LPEFMS.KPIASIVPAVTLIFLTEGVPLFFRWFSVVKCLKTGAQIEMDVQKWFFAFLFVHIFLVVTISSDISVV............VETVVN.............NPINIPHLLGTNL..P......KCSNFFCSFVLIRGIAYFGGNLLQSKNLFFYLFYYRWSN......RTPREKLKYKLNVPCYQWGSLYPIFSVLASITIIYS...VIAP..FVLPLASFSFIFVMFSFKYSLKYQFDHKNKSETL...GKFY..PQALMQLYSGIYFLEACLIGLF
Q75FA6_ASHGO/578-853                 RVALSNFLSVMVIVGWVIPVAFV.GLISQIPFLAKLVPLPSWS...AN..STSILDKSLSSIVPVMTLIFLTEGVPFLFRWFGWLKCCRSGSSTELDVQKWFFAFLFVHIFLVVTISSGISVI............VEKLVN.............NPVSIPDLLGTNL..P......KSSNFFCSFMLIRGLSYFGGNFMQVKSLL.FELFYYRWK.....VYTPRAVFERNVNVQQYQWGSVYPMFSVLACIGIIYC...VISP..IILLFASFSFALVMFSFKYSIKYQYNPVNNSESY...GKYY..PTALMQLYAGIYFLEICLIGLF
SPO75_YEAST/473-748                  KYFSANILRIFVIIGWILPVAFL.GLISQIPNISSLIPFTKII...HF.QSPFIR.EVAKNLIPIVTLIIIIEIVPYFFRWLSYLRGLKTGAQIEADVQNWYFVFVFIHLFVVVTISSGFSII............IERLLN.............NPVSIPALLANDL..P......KCANFFCSFVLIRGMAYAGGNLLRIKELL.FELFYYKWK.....RSTPHAQFKRLKTSLFFQLGSIYPIFSVLGCIGIIYS...VVAP..IILLLCCISFSMVFFSFSYLFKYQYNKENYSETF...GKLY..IQALMQLYAGIYFMEFCLLGLF
Q6FVT6_CANGA/490-765                 RKLAGRLIGVLVILGWIVPIAFI.GLVTQIPYLTNLLPYSNHF.....NVTSKCLRDVTKAVFPLVTLIFLTEFVPYIFRVISYLKGCRTGAEIEMDIQRWFFMFLLVHIFFVVTISSGLSLL............LEKLLI.............SPVSIPNILAHDL..P......KSSNFFCSFILLRGFAYSGGNIIRLKELFFEIVYYRPRM......PTPHNKMQRLKKNLFFQWGSIYPLFTVIGCICIIYS...IIAP..FILPLAVLSLSLVYYSFKYLFIYQFNSENISETH...GKLY..PEALSQLYAGIYCMELSLIGLF
Q0UCF6_PHANO/681-953                 RMFSVIVLIVALVIFWGIPVSAT.GALSQVNTLTEKVHFLRFI...NA.FPTWAI.SFVQGVLPPLFLAILFAILPILLRFLAGFTGTTTAGERELLVQNFYFAFVFVQLFLVVSISTGLTTA............IQKIVD.............NPISVPQTLAENL..P......KAANYFFSYMILQALSISSGTLLQIGAVVVIVFLR.FLD......TTPREKVSRVLSRPGINWGTMIPVYTNFGAIGIIYS...VVSP..LILIMMLITFSLFWFTYRYQMIYVSY.AKA.ETN...GLVY..PKAINQLFTGLYFLQLCLIGLF
Q2TX45_ASPOR/350-610                 RSISILVTLNVLAILWAIPISLT.GLLSQLVYLDSIDSHLHNL.......SDKEL.GAIQGLAPQMAASILMYCFPVVLQFLMKYYIAFERPAVEVLLQRHYFLFLYTQLFIVVSISSGVTTM............IPEIVN.............NVQSVPALLAKNL..P......KSGNYFYSYFLLQTVTQTALILFRLPDSLWMCLRRD................GKKHTLKEVRWSLLYPVFTNLICIGIIYS...IISP..LITLIGTMAFGIFLITHAYQSIYILE.ANE.DTA...GLLY..WEALNQLFVGVYTMDLFLIGLF
A1CSW7_ASPCL/666-938                 RTFGILTVVCAMVVGWAFPVAFT.GLLSQLSYLENAFTWLEWI...SK.LPDWLI.SAIQGILPPLFLAILMALLPLILRFLCRAQGAHTGMAIELTVQNYYFAFLFVQLFLVVAISSSFSTI............IDNVTN..............VTSWPELLAQNI..P......SSSNYFFSYMILQALSVSAGALVQIFGLVSWFILAPLLD......TTARKKWGRTTNLNQMQWGTFFPIYTTLASIGLIYC...VIAP..LILVFNIVTFGLFWFVYRYNTLYVTK.FRF.DTG...GLLF..PRAINQLFTGIYVMELSLIGLF
Q7SA72_NEUCR/767-1042                RSALVFAVVTGMLVLWAFPVAWT.ASLAQLDALVEKYSWLHWLV.ENK.TIHNVI.KGVAGVLPAAVLAILLILVPIALDWLATFQGAKTGSQTTETVQTYYFAFLFVQVFLVVSITSSTFQT............IANITQ.............DITSTPEVLAENL..P......KAANYFFSYMILQALSTSSGTLLQIGTLFMWYIMARILD......NTARAKWTRNTQLPSVTWGSFFPVYTNFACIALIYS...VVAP..LISIFAIITFALLWCAHRYNMLYVTR.FRT.DTG...GVLY..PRAINQTFTGLYVMELCLIGLF
Q0UR74_PHANO/392-666                 RWTAATAFISVMIIFFAVPVAFV.GLVSNINYLQQQFSWLRWI...GS.IPPVIL.GVITGLLPTVMLAVLMALVPIFCRFLAKTAGYVTWSQVELKTQSWYFAFQVVQVFLITTVASAATTV............VRSVIN.............DPGSALTVLSENL..P......KASNFYISYFILLGLSSAAGTLLNIGGFVVVVLLGRILP.....GKTPRKIFEKLTKLSGPSWGSEFPKWTNLAVIAITYS...GIAP..LMLGFAVIGFSLIYVAFRYNFLYVYE.SNI.ETK...GAAY..QKAMKHILVGCYLSELCLIGLF
#=GC SS_cons                         HHHHHHHHHHHHHHCTHHHHHHH.HCCH-SHHHHTTS---SSS......---SSHHCCHHHHHHHHHHHHHCCCHHHHHHHHHCCS--SBHHHHHHHHHHHHHHHHHHCTTHHHHHHHHHCHT............HHHHHH............STTSCHHHCHHHHH..H......HCHHHHHHHHHHHCHHHHHHHCCTHHHHHHHHHHHHHTT......TTTTTCCHHG.-S-S--HHHHHHHHHHHHHHHHHHC...CC-C..HHHHHHHHHHHHHHHHHHHHHCCS--.-S-.--S...STCH..HHHHHHHHHHHHHHHHHHHHHT
#=GC seq_cons                        +phhsshhlshlllhaslPVuhl.uhluslstLsphhPhLphl....t.hsthhh.ullsGlLPslhLslhhhllPhlhchluphpGhhopuphEhpshsphFhFhllplFLlsoluuushsh............lppllc.............pssslsphLApsL..P......ptusFalsYlllpulshsuhpLLplssLlhhhlhtthhs......pTPRchhpth.s.sshsaGshaPhhhhlhsIslsYu...lluP..lILsFuhlhFhlsahsa+YplhYlas.pph.-os...Gtha..PhshtplhhGlhlhplshlGlh
//