Summary: UcrQ family
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UcrQ family Provide feedback
The ubiquinol-cytochrome C reductase complex (cytochrome bc1 complex) is a respiratory multienzyme complex . This family represents the 9.5 kDa subunit of the complex.
Iwata S, Lee JW, Okada K, Lee JK, Iwata M, Rasmussen B, Link TA, Ramaswamy S, Jap BK; , Science 1998;281:64-71.: Complete structure of the 11-subunit bovine mitochondrial cytochrome bc1 complex [see comments] PUBMED:9651245 EPMC:9651245
External database links
This tab holds annotation information from the InterPro database.
InterPro entry IPR004205
The ubiquinol-cytochrome C reductase complex (cytochrome bc1 complex) is a respiratory multi-enzyme complex [PUBMED:9651245], which recognises a mitochondrial targeting presequence. The bc1 complex contains 11 subunits: 3 respiratory subunits (cytochrome b, cytochrome c1 and Rieske protein), 2 core proteins and 6 low molecular weight proteins. This family represents the 9.5 kDa subunit of the complex, known as subunit 8 or protein QP-C [PUBMED:12709789]. This subunit together with cytochrome B binds to ubiquinone.
The mapping between Pfam and Gene Ontology is provided by InterPro. If you use this data please cite InterPro.
|Molecular function||ubiquinol-cytochrome-c reductase activity (GO:0008121)|
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We make a range of alignments for each Pfam-A family:
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Curation and family details
|Seed source:||PSI-blast P13271|
|Number in seed:||7|
|Number in full:||257|
|Average length of the domain:||78.40 aa|
|Average identity of full alignment:||35 %|
|Average coverage of the sequence by the domain:||78.44 %|
|HMM build commands:||
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||11|
|Download:||download the raw HMM for this family|
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There are 8 interactions for this family. More...
We determine these interactions using iPfam, which considers the interactions between residues in three-dimensional protein structures and maps those interactions back to Pfam families. You can find more information about the iPfam algorithm in the journal article that accompanies the website.
For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe group, to allow us to map Pfam domains onto UniProt sequences and three-dimensional protein structures. The table below shows the structures on which the UcrQ domain has been found. There are 52 instances of this domain found in the PDB. Note that there may be multiple copies of the domain in a single PDB structure, since many structures contain multiple copies of the same protein seqence.
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