Summary: Triose-phosphate Transporter family
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Triose-phosphate Transporter family Provide feedback
This family includes transporters with a specificity for triose phosphate .
External database links
This tab holds annotation information from the InterPro database.
InterPro entry IPR004853This family consists entirely of aligned regions from Drosophila melanogaster proteins. SWISSPROT contains three repeats of this region. In other proteins, the aligned region is located towards the C terminus. The function of the aligned region is unknown.
- the number of sequences which exhibit this architecture
a textual description of the architecture, e.g. Gla, EGF x 2, Trypsin.
This example describes an architecture with one
Gladomain, followed by two consecutive
EGFdomains, and finally a single
- the UniProt description of the protein sequence
- the number of residues in the sequence
- the Pfam graphic itself.
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This clan contains a variety of transporters which have 4, 5, 9 or 10 membrane spanning helices. Many of the 10 membrane spanning transporters appear to be a duplication of the 5 spanning unit . Many of these families contain a characteristic glycine rich motif close to the C-terminus.
The clan contains the following 20 members:Cation_efflux CRCB CRT-like DUF1632 DUF486 DUF606 DUF914 EamA EmrE Mg_trans_NIPA Multi_Drug_Res Nuc_sug_transp RhaT Sugar_transport TPT UAA UPF0060 UPF0546 Ureide_permease Zip
We make a range of alignments for each Pfam-A family:
- the curated alignment from which the HMM for the family is built
- the alignment generated by searching the sequence database using the HMM
- Representative Proteomes (RPs) at 15%, 35%, 55% and 75% co-membership thresholds
- alignment generated by searching the NCBI sequence database using the family HMM
- alignment generated by searching the metagenomics sequence database using the family HMM
You can see the alignments as HTML or in three different sequence viewers:
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1Cannot generate PP/Heatmap alignments for seeds; no PP data available
Key: available, not generated, — not available.
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Curation and family details
|Seed source:||Pfam-B_3234 (release 6.5)|
|Author:||Mifsud W, Bateman A|
|Number in seed:||62|
|Number in full:||2906|
|Average length of the domain:||144.50 aa|
|Average identity of full alignment:||19 %|
|Average coverage of the sequence by the domain:||38.47 %|
|HMM build commands:||
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||11|
|Download:||download the raw HMM for this family|
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