Summary: Herpesvirus UL36 tegument protein
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Herpesvirus UL36 tegument protein Provide feedback
The UL36 open reading frame (ORF) encodes the largest herpes simplex virus type 1 (HSV-1) protein, a 270-kDa polypeptide designated VP1/2, which is also a component of the virion tegument. A null mutation in the UL36 gene of herpes simplex virus type 1 results in accumulation of unenveloped DNA-filled capsids in the cytoplasm of infected cells . This family only covers a small central part of this large protein.
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This tab holds annotation information from the InterPro database.
InterPro entry IPR005210
The UL36 open reading frame (ORF) encodes the largest Human herpesvirus 1 (HHV-1) protein, a 270 kDa polypeptide designated VP1/2, which is also a component of the virion tegument. A null mutation in the UL36 gene of herpes simplex virus type 1 results in accumulation of unenveloped DNA-filled capsids in the cytoplasm of infected cells [PUBMED:1331541]. The region which defines these sequences only covers a small central part of this large protein.
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|Molecular function||cysteine-type endopeptidase activity (GO:0004197)|
|omega peptidase activity (GO:0008242)|
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Curation and family details
|Seed source:||Pfam-B_3425 (release 7.0)|
|Number in seed:||11|
|Number in full:||176|
|Average length of the domain:||213.20 aa|
|Average identity of full alignment:||54 %|
|Average coverage of the sequence by the domain:||10.60 %|
|HMM build commands:||
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||8|
|Download:||download the raw HMM for this family|
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