# STOCKHOLM 1.0
#=GF ID Borrelia_P83
#=GF AC PF05262.12
#=GF DE Borrelia P83/100 protein
#=GF AU Moxon SJ;0000-0003-4644-1816
#=GF GA 33.6 33.6
#=GF NC 33.5 33.5
#=GF TC 33.9 34.5
#=GF SE Pfam-B_6712 (release 7.7)
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 47079205 -E 1000 --cpu 4 HMM pfamseq
#=GF TP Family
#=GF DR INTERPRO; IPR007926;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC This family consists of several Borrelia P83/P100 antigen
#=GF CC proteins.
#=GF SQ 17
O83499.1/23-473      RRELERA..NATVEFENFAGTH..TDVDSAAAIRRIGEGLASA........L.....R....GG..VAGDR...ARYALIHAVGPHTTNGFDADILIIGAQARVDHIDNIREIVAAYLSAAYGYRLQDARTIATFTTVYNAVYRADLPTFKARYKGVVTAHLSPEHVGIARRFDQWPGKTQLVIPLS--GHSDAL.SAVDTGAISDKRVVERLRED.PDK.NVDL.RRDMIDL..............................................KEREAQEGTRRAQQLAQQSQQAQERAAELSTQAQRAQ..AHADKTRREA...QQAQQA.......AQNSPDPAR..TQEAKEKERV...................A........-----.--ERA.QQ...EAQQAAHTAQKATEQ-..........AESLARE..ARSQEQ...................................RAQQKSA.EAQRERLEVAG.......................................DMQRMMNAGRAKATHGAQE....ARESVTPCY..GLKVVDAQ...H..LL..SEIVLVDPKTEAPLRSSSLRTVRNRLLYSEPHA.LVAIADT..TGNGTVR....LVHIDPKTLEVTKESTQRIAAQS.FLLR---ERGALL..CGDRRKW--------.-----------------
Q45013.2/28-672      EKLKDFV..NMDLEFVNYKGPY..DSTNTYEQIVGIGEFLARP........L.....T....NS..NSNSSy.yGKYFINRFIDDQDKKA-SVDVFSIGSKSELDSILNLRRILTGYLIKSFDYDRSSAELIAKVITIYNAVYRGDLDYYKGFYIEAALKSLSKENAGLSRVYSQWAGKTQIFIPLKKDILSGNIeSDIDIDSLVTDKVVAALLSE.NEA.GVNF.ARDITDIqgethkadqdkidieldnihesdsnitetienlrdqlekatdeehkKEIESQVDAKKKQ--KEELDKKAINLDKAQQKLDSAE..DNLDVQRNTV...REKIQEdineinkEKNLPKPGD..VSSPKVDKQLqike..........sledlQeqlketgdENQKR.EIEK-.QI...EIKKSDEKLLKSKDDKask....dgkALDLDRElnSKASSKekskakeeeitkgksqkslgdlnndenlmmpedqkLPEVKKL.DSKKEFKPVSEvekldkifksnnnvgelspldkssykdidskeetvnkdvNLQKTKPQVKDQVTSLNEDlttmSIDSSSPVF..-LEVIDPI...T..NL..GTLQLIDLNTGVRLKESTQQGIQRYGIYEREKD.LVVIKMD..SGKAKLQ....ILD-KLENLKVVSESNFEINKNS.SLYVDSKMILVAVrdKDSSNDWRLAKFSPKnLDEFILSENKIMPFTSF
S3K1E7.1/35-533      -------..ANSVVFINYTGPH..QIINTVEQIRSIGSGLGGS........IsansaR....ES..RAGQA...SRYYVIHAVDPSTTEKLDADILILGEQAIVDHIDNLRRIIAAYLESAYGYSRKDSQTLAVFVTVYNAVYRGKLDVFKQKYKTVVTKNLTADKAGLALNYAEWPGKTQIVIPLS-DVRSGGL.STVDTSVISDTKVIESMKKE.PDK.NIEQ.RKSMVTI..............................................KEKEAEKSQAKAEQSQKQATEAKKEATEAKKEATEAK..KEATEAKKVVtveKQKLEE.......AKKEAETAK..QKAAENPKDAea..............qkkA........AETKK.EAAKQ.QEkvaEAEKKADTAEKKAGEAeqkadtaekkADTLVKK..AEAEQI...................................IADKKQS.EAQKERIEIAK.......................................DQQQLIRES------AGLD....AI--INAAY..GLKITDEK...E..QL..SGLVLVDKKTGRTVKESPVTVIRNRVVYPAGKE.YIAVAGK.tGGNAAVR....LVKLDEKNMEIVAQSDEILAANS.VLVKDGAFYYVVI..-QDGKNYVAAKYDGN.LKQVLKSNVAVMPATPI
F4LNU4.1/31-502      --ELESVsaADTIVFVNYTGPH..AVIDSVDQIKGIGSSLGNV........I.....AsdpaAA..EAGLS...SRYYVIHAVDPNIAAGLDADILILGENATVDHIRNLRRIIAAYLSSAYGYTEKDAETLAVFITVYNAVYRGDTASFSAKYKPAVTKHLSAEKAGLALNYQDWPGKSQIVIPLA--NPAGGL.GTVDTTIISDKQVVQSMREE.EDK.GVDV.RKDMVDI..............................................KEREADAAAEQAADAQKQAAQAAVKQKEEEQKQTQAV..KEAETAQKQA...ETAQKE.......AAANPDDAQ..AQQRAAETAA...................E........AETKR.QAAEA.Q-...-TAKAEEQ----KQI-..........AEEKRTT..AAEQQA...................................AADKKRE.EARTDRTEIAK.......................................DQQQLIAE----------T....AEPPVNAAY..GLKMLDDT...-..-F..SVMVKLNAATGQVIRQSPVTVVRGRTLLPAGEN.YMAVAGQ.tGGNAAVK....LVLLDTVNMEIVAESKEQAAEKS.VLIRDGNDFYAVV..-QDQTGWIVGKYDAA.LSLTLKSKITVHPATPI
F8F1S9.1/29-508      --ELEST.rNSSILFISYEGPH..GRIETREDIRGIGYALGRA........I.....K....AGalRAGST...NRYFAIHSVTTGTTQL-DADIFGLGIDVGVDHIKNLRLILQGYLEGAYDYSASDAALLAQFITIYNAVYRGNWNYVTSRYTPKVVSELTKEKTGLSIRFDEWPGQSLILIPLA-IGQAGSL.SAIDTSQITQKPVIEQLKKD.KDL.GLDA.RKDMVDL..............................................KEREAQEAKQTAQVQKEAIAQEEARLAAEKAALEQDK..AYLAEEKTRA...EQASEK.......AGSVQQSGT..VKAAAESKKA...................D........EKTLS.PQELAaKE...ETIRAQEQAIAKKEQA..........LEAQKQE..VAAAEA...................................RAAQKEQ.EAKAERAEIAK.......................................DQQQVIQRQEAAKTVP---....-----EGLL..GISLLQNT...N..AL..GRLVLVNPTNGTAMKQSTLNTINSRAMLILPDK.IIAIAGQ.aQGSGAVR....LVQIDPKSLEMLKQGDVDIASTS.LLWAQGQDIFALA..-NTSGKLYLARFDQN.LQLLNKSTTEIHPFAS-
A0A1Y1RTC9.1/33-483  -------..-GTVEFVNYEGPH..ERIDTLAQILGIGRSLAAG........L.....A....EG..GEGFLf.dGKYRVRRIFDAGA-VLLSADIFILEPDARVDHVRNLRRILAAYLSQAFDYSFADAEILAEFATYYNAVYRGDMEYIGQKYQDRVVSNLDPDKAGLATVYSQWPGKTQMLLPLRVLPLSGGI.GAVDMDTLTEDEVIAKLQED.EDK.GIPE.RKEMTEL..............................................KEKEIEADEERIDSARAEIAEDEAEISAEEQQLEAER..QDLERRRDEA...AAIEDE.......GERAAEEAA..IAAAEEDV--...................S........-----.-----.QR...EA------ALDERREA..........VDEQKEE..VARAEQ...................................DVQERVE.RIREEREEIAS.......................................DERGILEDQREEAPPE---....-----VP-F..-LYIVEGR...E..NF..RMLVSALSGTGEIRRRSGINTIRSRDLLILGDS.YLVVAGE.tGGNKAVR....LVTIDPVSFEMKNQGDTDMYPMS.FLLLDRRNVYGIA..--DSNGYRVARFNTD.LSLQALSEVTVNPDT--
G0GA20.1/32-494      -------..DAEVTFVNYEGPH..EKIETIEQIRGIGIALAGGr......dY.....T....AP..FTADY..aGKYRIIHAVDPATPVGLDADIMEILPSARVDHILNLRRIISGYLQEAYGYSPEDAATLAFFITIYNAVLRGNITYFQEMYKPVVVRHLRTDTVGLSRHYRDWPGGSQIVIPLSEGAARTDI.TAVETQALTGPEVIQELKTR.EDK.AIPE.RKEMVEI..............................................KEKQIEEEKAALEAQKQEVTEEETRLAEEKAVLEAQK..QTLEQEKARV...EETLAQ.......AP--PGSEE..ERQAL-----...................-........-EEKR.AVEEK.EA...EIARMEEETA-EKETR..........IEEEKTE..IARKEI...................................EIEKKEE.AVKREREDIAR.......................................DQEKVMAQQ-------AE-....AAPERVPVV..--EVTDPE...G..LM.kSRFLLLDTTTYEPVAGAGLTIVGRTPVPFSGGY.LVIVPRD..GTTGTLT....LVD--ARTLDILRECADPVSIQS.LIEVHEGNVYAVF..-QKEGRWHVGRFDQN.LVRLAYTREEVAPYTSF
A0A3P5VSK0.1/36-310  -------..DQSIKFINYVGPY..EFINTADQILGIGRFLGSG........I.....T....PE..ISGKNsigGKYEVVHIVEPSIEQGFDSDVFIVGNDAAVDHINNLRTIIAGYLETVYDFSRRDAYLIAEFITYYNAVYRKDMEMVRERYKEPVVNFLNPDFLGLDTHYSNWAGKTQMLIPLGTKFDSGT-.-SVDAGAIADDQVVEEMRKE.EDM.GLDS.RRGMVEL..............................................REREIIKEQENLDKLRGELESKRKSISEKLDDFEEKE..EP-GLEERAV...REELEK.......DKSSVEKAI..EELEELQKKV...................D........EETKE.V----.--...----------------..........-------..------...................................-------.-----------.......................................-------------------....---------..--------...-..--..---------------------------------.-------..-------....-----------------------.-------------..---------------.-----------------
A0A3P5VSK0.1/340-471 -------..-------------..-------------------........-.....-....--..-----...-------------------------------------------------------------------------------------------------------------------------.--------------------.---.----.-------..............................................-------------------------------------..----------...------.......---------..----------...................-........-----.-----.--...----------------..........-------..------...................................-------.-----------.......................................-------------------....-----EPIW..FLTVDNEG...D..GIpyGRVVKYNSENSELLAVSKLTAVRGRSMAILPDS.IIVIAGR.rGSNSKVR....LMLLDRNTLETISVGEHDIFPGS.LMMMDGSDIYLVT..-TEKGEWRLGKFDTT.MNRTAISQLAITPWTSI
E1R687.1/43-506      -------..--SVEFLNYEGPH..QKIESAGQIRGIGAAMA--........-.....-....EG..RSSSY..lGKYRIISIV-PSSPDVLGADIVEILDGALVDHIDNVRRILSGFVAAKYGYDQEKADTIALFTTYYNAVHRGDLEYVRSRYTEAVLSRLDEKKMGISTSYKEWPGNTQMLIPLS---LDGTGsARISADTVGGDEVVQELRSD.ESKqGLDD.RKSMVEL..............................................REDQLEEDKAATAEERNQLEEDTVDLQQKQEAAEAQQ..EEIDRRQDEV...ASALEG.......----AEPGS..TKEAELKGQQ...................E........ELAKQ.E-EQ-.VQ...AAKQELEEQQQALDKQ..........EEQ----..VAAKEK...................................EQASREE.AIGQERDRIAG.......................................DEQKTIAEEEAAARQRA--....-AGATAPGF..TFMHVREE...NgiIL..SSMVIYDSESGKERGRSAVNAIRGRKVYPVSGAyLAVVGMD..APPKAVK....LMLLNSDDLSVSSESEQHLYGES.WVLLDNQRAYVVA..-SFDGIWKIAAFDSGnLSLLAQSDVEVDPNTV-
A0A370AHL7.1/44-495  -------..--EIIFENYVGPTapEEFNTMDQISGIGSFLASQ........-.....D....GT..EIQYG...NKYKIIRSYQPEIKEGLDGDILFILPDAAVDHIRNLRSIIATYLKATFGYSDSNAAVLAEFVTYYNAVYYKNIDHYSSRYKEGVLKNLEKNSAGLSTHYSEWAGKSRIVIPLK--SGDGTIqSSLDTSTISEPEVIEEMQKE.DDK.ALDS.RKEMVEI..............................................REDE--LDTRQES-----VDEEKKAVEEKETAVQEKE..EVIDQQLEEK...KEELEQ.......--------V..DEGSPEELVI...................Q........EEVKQlEEEKA.EV...EEEKAAVEEEKA----..........AVEETQE..QI----...................................--DDEQK.EVVEMREDIAR.......................................DENELAKEKGVVLSSGDQV....PPEGFWFIF..VDKSADPA...P..FG..SLLKV--TKTGEILQKSELNSIRGTSFIEGVEG.LIVIAGK.nEENARVK....ALILDPETLEVVKEGENEIYPGS.SIWTEGDNLFMIT..-RNEQNWSVGMFSKS.LDLQKLSTVNVHPDT--
H9UKC6.1/37-334      -------..--DIEFENFPGIP..ERIDTAEEIRSIGRFLGQA........R.....E....LG..QTDRVf.aGRYRIVRAVDPEETGKLDADIIYLLPDARVDHVDNIRRIIAGYLETTYGYQTTDATLLSRFITIYNAVHRRDMEFFDARYKTVVMANLSPAGAGLPLSWREWPGGSEIVIPIRDPDAMDRL.GIISPGELIDRAVLDDLRTR.RDM.GLED.RRDMIDFfe.........................................rliAEEEAEIALEREQ-IEREREELAEERERIEEEREIAV..DDPDTDPDVE...PEEPDDpdeiverERELEEREE..RLTEREDD--...................V........EQLRE.EVERL.RE...ETAEDQEL--------..........-------..------...................................-------.-----------.......................................-------------------....---------..--------...-..--..---------------------------------.-------..-------....-----------------------.-------------..---------------.-----------------
I4B9F6.1/41-483      -------..-------------..AGGDSVSAIQGIGTSLASQ........-.....-....--..--GKF...GSYSVIHATGAGDDKF-DADIIVIGKDARVDHIKNVRRIIAAYLQQRYSYSAEDAKSLAVFITYYNGFYRKNLGYFKEHYKSAVLKHLSASNAGLDLSYKGWPGKSRIVIPLSDDAK----.--PDAGKIGEKDVMDKVRKDeKDK.GVKD.RENITKL..............................................QDKEVKKKEERLEKKKEELTKRRDDISKKEQRLNEEK..KKNAEN-PDP...NDKAKK.......DEELKKKED..E-LAKEK---...................-........DNLKK.DEEKT.AK...EEKKVAEKKN----EV..........AENKKSV..QDDKAA...................................NATRKNE.TAAQKEARLDS.......................................KEQELKKREEAQKNNRKED....GVFGGKMYY..-LRVRDYStdgK..YR..NDFYIIDPKERKVKVKSPFAGIVGKKYDVVDKD.VVVIGEKrsATTTSHY....LVKLDGETLVDKQYGSDEIFWRG.FVEVRENEIYAIL..-NKNGTFYLGKFDKE.LKLLQRSEVA-------
A0A098R4G2.1/30-371  ----SSL..DRTIQFENYAGPV..EKFETAQEIRSIGTAFVNQlgrtedgrL.....A....AG..NAGYF...GKYRLFHIPPVPGQPGRGADILELLPNAQVDHIDNLRRILSAYLESAYGYSPEDAQTLGVFVTLYNAIHRGAYPRFQERYNGEVMGILRPEHLGIALSYREWPGATQLVIPLAVDSPPGQL.STVPADELASPEVVETLRDQ.PDR.GIEE.RQQVVDL..............................................IDRSVEQETDQIQEQRRILESTQQEPAQPAEETPGSEpsAASEDARSPA...QTPGDA.......AQPRETPEAqsPSSPEQQPQTdspadspaapevtpseqpsEe......sPEPET.QTPVT.QE...QLDQREEELRQAQER-..........SDEIRQE..TAQ---...................................-------.-----------.......................................-------------------....---------..--------...-..--..---------------------------------.-------..-------....-----------------------.-------------..---------------.-----------------
A0A1N6QU21.1/53-298  ---LEAA.aGADIEFESFLGEV..QQFDTAQAIRGIGSALGQG........A.....A....ED..ETYDY..fNRYIIRRIIGDPLDRRRAADIIEFSPAARVDHIENVRRILSEFLITAWGYQRGDADLLARFITIYNAVHRGDMDFFVARYREAVSNALDPQRVGIALSYRDWPGQTQMVVPLRGGRDPGDL.DAVDPGQLVGPAVIGDLRSR.ADL.GIDD.RKAIIEFiervvevrl............................deialeraeIEEEREEIARRREDLQQDP-APALDAD----------..----------...------.......---------..----------...................-........-----.-----.--...----------------..........-------..------...................................-------.-----------.......................................-------------------....---------..--------...-..--..---------------------------------.-------..-------....-----------------------.-------------..---------------.-----------------
Q8F932.1/35-513      -------..--RVRFINRSSAR..AGEEVRGTNEKVGSGLAES........L.....K....KE..PDKTHt.qGGISVTRIA-PEEKR-FGADVISVLEDSDFGHINSIQRILTGFVKLNFGYDDKNSDILATYILYYNAIHRKDKSYISKKYSNSVIKFVTPQSIGISKRYSEWPGKTQILIPLVEDVLG---.KDVHTDELED-EVNKELDKK.KDG.QSEK.-DKFGDL..............................................QNEKNKKELEELKRRKEENQNKQKEISDKETKTDKEL..QE--LNKDPV...KNKVQI.......VEKKKEKEQ..IQKEKEAVKK...................E........EQKLK.EKEK-.--...EVVKKDEERKNNNSSSss......ssS----SS.sSKSDSSs................................skSGSDKSAsDDKKSEAELKKe....................................laDTKKELETKKEEEKKKEEFd..kNVVGGKILFlkTLKYLDKG...H..YN..NELQVLDPTKDDTIIRGDFNKICGRTFEIVDGK.ALVIGFE.dGHSSNHK....LILIDQETLKPVLFAEDNIFWRS.PMIIKGDEIYAFE..-EVEEKYYLSRFGKD.LKKQAKSSEEISPN---
H2CGQ5.1/40-529      -------..--TVRFENRTNRR..ATPAARQYERNLGIRIAEN........A.....I....ND..RTAPV...ADIQIFRVFDAN-KEKYGADVIVLGPKTDFGHILAIQRVIAGYLERAFEFKPEQAETMSLFIIYYNAEIRSRPELIEKSFSDAVIAKLDAKKAGIDRSYKNWPGKTMILIPLRKNVVRPDK.ADIDREEIKKET-------E.DNK.DVKKdEKDALDKv............................................dAERTKDDQTKL-DQKKSELDIKQEQIDQQKKDLEKEE..QEFKKDLVDT...GKKLEE.......LRKDPVKNA..VEIKKEEQKQ...................Qd......lAKKQE.EVKKQ.QE...EVKKQEQTVTQEKKE-..........VQEQKTDtpSRQEEKkdqsts.......................ttdttkTEEQKKE.EVKKD-ETIA-.......................................NLQKEKEELQKEIEKKEELs.enVVLEKILFM..RVQSIEKG...H..YS..NELWYVDTNKDDTLFRSPFTKICSRDFVAVPDQ.GVMVAGY..AGDSHEQsdhfLVLLDPENLEFKKQSNESVFWNTpMILRDGKIYA--V..ESFNGQYFLSRFNPD.LTLDARSSEGMSPH---
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