Summary: Branched-chain amino acid transport protein
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Branched-chain amino acid transport protein Provide feedback
This family consists of several bacterial branched-chain amino acid transport proteins which are responsible for the transport of leucine, isoleucine and valine via proton motive force .
Stucky K, Hagting A, Klein JR, Matern H, Henrich B, Konings WN, Plapp R; , Mol Gen Genet 1995;249:682-690.: Cloning and characterization of brnQ, a gene encoding a low-affinity, branched-chain amino acid carrier in Lactobacillus delbruckii subsp. lactis DSM7290. PUBMED:8544834 EPMC:8544834
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This tab holds annotation information from the InterPro database.
InterPro entry IPR004685Characterised members of the branched chain Amino Acid:Cation Symporter (LIVCS) family transport all three of the branched chain aliphatic amino acids (leucine (L), isoleucine (I) and valine (V)) [PUBMED:8544834]. They function by a Na+ or H+ symport mechanism and display 12 putative transmembrane helical spanners.
The mapping between Pfam and Gene Ontology is provided by InterPro. If you use this data please cite InterPro.
|Cellular component||integral component of membrane (GO:0016021)|
|Molecular function||branched-chain amino acid transmembrane transporter activity (GO:0015658)|
|Biological process||branched-chain amino acid transport (GO:0015803)|
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This large superfamily contains a variety of transporters including amino acid permeases that according to TCDB belong to the APC (Amino acid-Polyamine-organoCation) superfamily.
The clan contains the following 20 members:AA_permease AA_permease_2 AA_permease_C Aa_trans BCCT BenE Branch_AA_trans CstA HCO3_cotransp K_trans MFS_MOT1 Na_Ala_symp Nramp SNF Spore_permease SSF Sulfate_transp Transp_cyt_pur Trp_Tyr_perm Xan_ur_permease
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Curation and family details
|Seed source:||Pfam-B_1869 (release 8.0)|
|Number in seed:||18|
|Number in full:||1621|
|Average length of the domain:||406.10 aa|
|Average identity of full alignment:||34 %|
|Average coverage of the sequence by the domain:||96.41 %|
|HMM build commands:||
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 26740544 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||12|
|Download:||download the raw HMM for this family|
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