# STOCKHOLM 1.0
#=GF ID EB1_binding
#=GF AC PF05937.12
#=GF DE EB-1 Binding Domain
#=GF AU Yeats C;0000-0003-0080-6242
#=GF GA 25.0 25.0
#=GF NC 22.7 24.9
#=GF TC 35.3 88.8
#=GF SE Yeats C
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 47079205 -E 1000 --cpu 4 HMM pfamseq
#=GF TP Family
#=GF RN [1]
#=GF RM 11514192
#=GF RT The adenomatous polyposis coli protein: in the limelight out at
#=GF RT the edge. 
#=GF RA Dikovskaya D, Zumbrunn J, Penman GA, Nathke IS; 
#=GF RL Trends Cell Biol 2001;11:378-384.
#=GF DR INTERPRO; IPR009232;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC This region, found at the C-terminus of the APC proteins, binds
#=GF CC the microtubule-associating protein EB-1 [1]. At the C-terminus
#=GF CC of the alignment is also a Pfam:PF00595 binding domain. A short
#=GF CC motif in the middle of the region appears to be found in the
#=GF CC APC2  proteins (e.g Swiss:O95996).
#=GF SQ 12
M7C609.1/2684-2857     RSGRSPTGNTPPVIDSVLEKG...N.ANGKDSKDIQGKQNAGNGNVPVRTMGLENRLNSFIQIDSPDKKGTETKPVLSNPVPAPETNESIINERTPFSSSSSSKHSSPSGAVAARVTPFNYNPSPRKSSADNSSARPSQIPTPVNNSTKKRDSKTENTDSSGTQSPKRHSGSYLVTSV
P25054.2/2670-2843     RSGRSPTGNTPPVIDSVSEKA...N.PNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIVERTPFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKTDSTESSGTQSPKRHSGSYLVTSV
A0A1D5PKD1.2/2519-2692 RSGRSPTGNTPPVIDSVSEKG...V.VNGKDSKEIQEKQNPGNGSVPVRTIGLENRLNSFFQMDSPDKKGNETKPLQTNPVPAPENNESTVSERTPFSSSSSSKHNSPIGAVAARVTPFNYNPSRRKSSVDNSSARPSQIPTPVNNSTKKRDSKSENTDSSGTQSPKRHSGSYLVTSV
A0A3Q2UHV9.1/2645-2818 RSGRSPTGNTPPVIDSVSEKG...V.VNGKDSKEIQEKQNPGNGSVPVRTIGLENRLNSFFQMDSPDKKGNETKPLQTNPVPAPENNESTVSERTPFSSSSSSKHNSPIGAVAARVTPFNYNPSRRKSSVDNSSARPSQIPTPVNNSTKKRDSKSENTDSSGTQSPKRHSGSYLVTSV
E1BZS9.3/2668-2841     RSGRSPTGNTPPVIDSVSEKG...V.VNGKDSKEIQEKQNPGNGSVPVRTIGLENRLNSFFQMDSPDKKGNETKPLQTNPVPAPENNESTVSERTPFSSSSSSKHNSPIGAVAARVTPFNYNPSRRKSSVDNSSARPSQIPTPVNNSTKKRDSKSENTDSSGTQSPKRHSGSYLVTSV
A0A1D5PC88.1/2680-2853 RSGRSPTGNTPPVIDSVSEKG...V.VNGKDSKEIQEKQNPGNGSVPVRTIGLENRLNSFFQMDSPDKKGNETKPLQTNPVPAPENNESTVSERTPFSSSSSSKHNSPIGAVAARVTPFNYNPSRRKSSVDNSSARPSQIPTPVNNSTKKRDSKSENTDSSGTQSPKRHSGSYLVTSV
A0A3M0IVX7.1/47-220    RSGRSPTGNTPPVIDSVSEKG...G.VNGKDPKEIQEKQIPGNGSVPVRTIGLENRLNSFFQIDSPDKKGTETKPLQNNLIPAPEINESTVNERTPFSSSSSSKHSSPIGAVAARVTPFNYNPSRRKSSVDNSSARPSQIPTPVNNSTKKRDTKSENTDSNGTQSPKRHSGSYLVTSV
P70478.1/2670-2842     RSGRSPTGNTPPVIDSISEKG...N.PSIKDSKDTQGKQSVGSG-SPVQTVGLENRLNSFIQVEAPEQKGTETKAGQGSPAPVAETGETCMAERTPFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVGSSTKKRDSKTDSTESSGAQSPKRHSGSYLVTSV
Q61315.1/2670-2845     RSGRSPTGNTPPVIDSVSEKGsssI.KDSKDSKDTHGKQSVGSG-SPVQTVGLETRLNSFVQVEAPEQKGTEAKPGQSNPVSIAETAETCIAERTPFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVSTNTKKRDSKTDITESSGAQSPKRHSGSYLVTSV
A0A401PZC5.1/2557-2729 RPGKSPTGNTPPVIDDVPEKL...LlSDEEGSGDGQNK--PASEHRTTHGVRMEKCLNSFTQLDSPEKKATETKCAVNSSATSPEIETTVVTERTPFSSNSSSKHNSPSGTVAARVTPFNYVPSPRKSSTDNSSTRPSQIPTPVNNNKRKESSKPETTESSGNQSPKRHSGSYLVTSV
F8W4Z3.1/2584-2739     RSSKSPTASTPPVIDSLPIKG...L.ACDRDSSESHSK--LMSENAAMSHLGSETNLNLLRSSESLDKKVTDIKPAPSNPNIGPELHEFPVSERTPFSSTNSSKHSSPSGAVAARVSPFNYTPSPRKSSADGSTPRPSQIPTPISSNAKKRDTKGDTTES----------GS------
A0A0R4IWH7.1/2593-2748 RSSKSPTASTPPVIDSLPIKG...L.ACDRDSSESHSK--LMSENAAMSHLGSETNLNLLRSSESLDKKVTDIKPAPSNPNIGPELHEFPVSERTPFSSTNSSKHSSPSGAVAARVSPFNYTPSPRKSSADGSTPRPSQIPTPISSNAKKRDTKGDTTES----------GS------
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