Summary: Cytomegalovirus UL84 protein
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Cytomegalovirus UL84 protein Provide feedback
This family consists of several Cytomegalovirus UL84 proteins. The open reading frame UL84 of human cytomegalovirus encodes a multifunctional regulatory protein which is required for viral DNA replication and binds with high affinity to the immediate-early transactivator IE2-p86 .
Lischka P, Sorg G, Kann M, Winkler M, Stamminger T; , J Virol 2003;77:3734-3748.: A nonconventional nuclear localization signal within the UL84 protein of human cytomegalovirus mediates nuclear import via the importin alpha/beta pathway. PUBMED:12610148 EPMC:12610148
External database links
This tab holds annotation information from the InterPro database.
InterPro entry IPR010436
This family consists of several Cytomegalovirus UL84 proteins. The open reading frame UL84 of human cytomegalovirus encodes a multifunctional regulatory protein which is required for viral DNA replication and binds with high affinity to the immediate-early transactivator IE2-p86 [PUBMED:12610148].
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This clan contains dUTPase and many viral proteins that appear to be related. dUTPases are important in virus replication.
The clan contains the following 7 members:Cytomega_UL84 DCD DUF570 dUTPase Herpes_ORF11 Herpes_U55 Herpes_UL82_83
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Curation and family details
|Seed source:||Pfam-B_11948 (release 9.0)|
|Number in seed:||4|
|Number in full:||46|
|Average length of the domain:||419.40 aa|
|Average identity of full alignment:||53 %|
|Average coverage of the sequence by the domain:||97.45 %|
|HMM build commands:||
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||6|
|Download:||download the raw HMM for this family|
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