Summary: Flagellar regulatory protein FleQ
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Flagellar regulatory protein FleQ Provide feedback
This domain is found at the N terminus of a subset of sigma54-dependent transcriptional activators that are involved in regulation of flagellar motility e.g. FleQ in Pseudomonas aeruginosa. It is clearly related to PF00072 but lacks the conserved aspartate residue that undergoes phosphorylation in the classic two-component system response regulator (PF00072).
Jyot J, Dasgupta N, Ramphal R; , J Bacteriol 2002;184:5251-5260.: FleQ, the major flagellar gene regulator in Pseudomonas aeruginosa, binds to enhancer sites located either upstream or atypically downstream of the RpoN binding site. PUBMED:12218010 EPMC:12218010
Dasgupta N, Ramphal R; , J Bacteriol 2001;183:6636-6644.: Interaction of the antiactivator FleN with the transcriptional activator FleQ regulates flagellar number in Pseudomonas aeruginosa. PUBMED:11673434 EPMC:11673434
Internal database links
|Similarity to PfamA using HHSearch:||Response_reg|
This tab holds annotation information from the InterPro database.
InterPro entry IPR010518
This domain is found at the N terminus of a subset of sigma54-dependent transcriptional activators that are involved in regulation of flagellar motility e.g. FleQ in Pseudomonas aeruginosa. It is clearly related to INTERPRO, but lacks the conserved aspartate residue that undergoes phosphorylation in the classic two-component system response regulator (INTERPRO).
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Curation and family details
|Seed source:||Pfam-B_13480 (release 9.0)|
|Number in seed:||45|
|Number in full:||94|
|Average length of the domain:||112.60 aa|
|Average identity of full alignment:||25 %|
|Average coverage of the sequence by the domain:||23.27 %|
|HMM build commands:||
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 11927849 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||8|
|Download:||download the raw HMM for this family|
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