Summary: Activator of aromatic catabolism
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This domain is found at the N terminus of a subset of sigma54-dependent transcriptional activators in several proteobacteria, including activators of phenol degradation such as XylR. It is found adjacent to PF02830.
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External database links
This tab holds annotation information from the InterPro database.
InterPro entry IPR010523
This domain is found at the N terminus of a subset of sigma54-dependent transcriptional activators in several proteobacteria, including activators of phenol degradation such as XylR. It is found adjacent to INTERPRO.
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This clan contains families that bind small molecules and are predominantly involved in signalling. Members include the heme NO binding domain. This domain is related to soluble guanylate cyclases and is mainly alpha helical in structure. Other members of this clan include V4R, which is predicted to be a small molecule binding domain, and a domain often found adjacent to this that is found on activators of aromatic catabolism, and on signalling molecules.
The clan contains the following 3 members:HNOB V4R XylR_N
We make a range of alignments for each Pfam-A family:
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Curation and family details
|Seed source:||Pfam-B_2890 (release 9.0)|
|Number in seed:||16|
|Number in full:||223|
|Average length of the domain:||101.30 aa|
|Average identity of full alignment:||39 %|
|Average coverage of the sequence by the domain:||18.53 %|
|HMM build commands:||
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||6|
|Download:||download the raw HMM for this family|
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