Summary: Splicing factor 3B subunit 10 (SF3b10)
Splicing factor 3B subunit 10 (SF3b10) Provide feedback
This family consists of several eukaryotic splicing factor 3B subunit 10 (SF3b10) proteins. SF3b10 is a 10 kDa subunit of the splicing factor SF3b. SF3b associates with the splicing factor SF3a and a 12S RNA unit to form the U2 small nuclear ribonucleoproteins complex. SF3b10 and SF3b14b are also thought to facilitate the interaction of U2 with the branch site .
Will CL, Urlaub H, Achsel T, Gentzel M, Wilm M, Luhrmann R; , EMBO J 2002;21:4978-4988.: Characterization of novel SF3b and 17S U2 snRNP proteins, including a human Prp5p homologue and an SF3b DEAD-box protein. PUBMED:12234937 EPMC:12234937
External database links
This tab holds annotation information from the InterPro database.
InterPro entry IPR009846
This family consists of several eukaryotic splicing factor 3B subunit 5 (SF3b5) proteins. SF3b5 is a 10 kDa subunit of the splicing factor SF3b. SF3b associates with the splicing factor SF3a and a 12S RNA unit to form the U2 small nuclear ribonucleoproteins complex. SF3b5 and SF3b14b are also thought to facilitate the interaction of U2 with the branch site [PUBMED:12234937]. Also included in this entry is RDS3 complex subunit 10, another protein involved in mRNA splicing [PUBMED:15565172].
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Curation and family details
|Seed source:||Pfam-B_16870 (release 10.0)|
|Number in seed:||19|
|Number in full:||296|
|Average length of the domain:||77.40 aa|
|Average identity of full alignment:||49 %|
|Average coverage of the sequence by the domain:||82.45 %|
|HMM build commands:||
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||6|
|Download:||download the raw HMM for this family|
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