Summary: Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
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Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Provide feedback
This family contains subunit 1 of bacterial heptaprenyl diphosphate synthase (HEPPP synthase) ( EC:22.214.171.124) (approximately 230 residues long). The enzyme consists of two subunits, both of which are required for catalysis of heptaprenyl diphosphate synthesis .
Zhang YW, Koyama T, Marecak DM, Prestwich GD, Maki Y, Ogura K; , Biochemistry 1998;37:13411-13420.: Two subunits of heptaprenyl diphosphate synthase of Bacillus subtilis form a catalytically active complex. PUBMED:9748348 EPMC:9748348
Internal database links
This tab holds annotation information from the InterPro database.
InterPro entry IPR009920
This family contains subunit 1 of bacterial heptaprenyl diphosphate synthase (HEPPP synthase) (EC) (approximately 230 residues long). The enzyme consists of two subunits, both of which are required for catalysis of heptaprenyl diphosphate synthesis, the precursor for the side chain of the isoprenoid quinone menaquinone-7 (MQ-7) [PUBMED:9748348, PUBMED:9720033].
|Biological process||menaquinone biosynthetic process (GO:0009234)|
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This superfamily includes a diverse range of terpene synthase enzymes which share an alpha helical core.
The clan contains the following 6 members:HEPPP_synt_1 polyprenyl_synt SQS_PSY Terpene_synth_C TRI5 UbiA
We make a range of alignments for each Pfam-A family:
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1Cannot generate PP/Heatmap alignments for seeds; no PP data available
Key: available, not generated, — not available.
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Curation and family details
|Seed source:||Pfam-B_18592 (release 10.0)|
|Author:||Vella Briffa B|
|Number in seed:||15|
|Number in full:||202|
|Average length of the domain:||202.80 aa|
|Average identity of full alignment:||25 %|
|Average coverage of the sequence by the domain:||77.87 %|
|HMM build commands:||
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 26740544 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||10|
|Download:||download the raw HMM for this family|
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