Summary: Neutral trehalase Ca2+ binding domain
Neutral trehalase Ca2+ binding domain Provide feedback
Neutral trehalases mobilise trehalose accumulated by fungal cells as a protective and storage carbohydrate. This family represents a calcium-binding domain similar to EF hand. Residues 97 and 108 in O42893 have been implicated in this interaction. It is thought that this domain may provide a general mechanism for regulating neutral trehalase activity in yeasts and filamentous fungi .
Franco A, Soto T, Vicente-Soler J, Paredes V, Madrid M, Gacto M, Cansado J; , Biochem J 2003;376:209-217.: A role for calcium in the regulation of neutral trehalase activity in the fission yeast Schizosaccharomyces pombe. PUBMED:12943532 EPMC:12943532
External database links
This tab holds annotation information from the InterPro database.
InterPro entry IPR011120
Neutral trehalases mobilise trehalose accumulated by fungal cells as a protective and storage carbohydrate. This family represents a calcium-binding domain similar to EF hand. Residues 97 and 108 in SWISSPROT have been implicated in this interaction. It is thought that this domain may provide a general mechanism for regulating neutral trehalase activity in yeasts and filamentous fungi [PUBMED:12943532].
The mapping between Pfam and Gene Ontology is provided by InterPro. If you use this data please cite InterPro.
|Cellular component||cytoplasm (GO:0005737)|
|Molecular function||alpha,alpha-trehalase activity (GO:0004555)|
|calcium ion binding (GO:0005509)|
|Biological process||trehalose catabolic process (GO:0005993)|
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Curation and family details
|Author:||Finn RD, Bateman A, Wood V, Studholme DJ, Moxon SJ|
|Number in seed:||19|
|Number in full:||181|
|Average length of the domain:||30.00 aa|
|Average identity of full alignment:||62 %|
|Average coverage of the sequence by the domain:||4.12 %|
|HMM build commands:||
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||6|
|Download:||download the raw HMM for this family|
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