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49  structures 1255  species 0  interactions 4728  sequences 81  architectures

Family: Tannase (PF07519)

Summary: Tannase and feruloyl esterase

Pfam includes annotations and additional family information from a range of different sources. These sources can be accessed via the tabs below.

The Pfam group coordinates the annotation of Pfam families in Wikipedia, but we have not yet assigned a Wikipedia article to this family. If you think that a particular Wikipedia article provides good annotation, please let us know.

This tab holds the annotation information that is stored in the Pfam database. As we move to using Wikipedia as our main source of annotation, the contents of this tab will be gradually replaced by the Wikipedia tab.

Tannase and feruloyl esterase Provide feedback

This family includes fungal tannase [1] and feruloyl esterase [2-3]. It also includes several bacterial homologues of unknown function.

Literature references

  1. Hatamoto O, Watarai T, Kikuchi M, Mizusawa K, Sekine H; , Gene 1996;175:215-221.: Cloning and sequencing of the gene encoding tannase and a structural study of the tannase subunit from Aspergillus oryzae. PUBMED:8917102 EPMC:8917102

  2. de Vries RP, vanKuyk PA, Kester HC, Visser J; , Biochem J 2002;363:377-386.: The Aspergillus niger faeB gene encodes a second feruloyl esterase involved in pectin and xylan degradation and is specifically induced in the presence of aromatic compounds. PUBMED:11931668 EPMC:11931668

  3. Kroon PA, Faulds CB, Williamson G; , Biotechnol Appl Biochem 1996;23:255-262.: Purification and characterization of a novel esterase induced by growth of Aspergillus niger on sugar-beet pulp. PUBMED:8679110 EPMC:8679110


Internal database links

This tab holds annotation information from the InterPro database.

InterPro entry IPR011118

This family includes fungal tannase [ PUBMED:8917102 ] and feruloyl esterase [ PUBMED:11931668 , PUBMED:8679110 ]. It also includes mono(2-hydroxyethyl) terephthalate hydrolase from the bacterium Ideonella sakaiensis [ PUBMED:26965627 ] and several bacterial homologues of unknown function.

Domain organisation

Below is a listing of the unique domain organisations or architectures in which this domain is found. More...

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Alignments

We store a range of different sequence alignments for families. As well as the seed alignment from which the family is built, we provide the full alignment, generated by searching the sequence database (reference proteomes) using the family HMM. We also generate alignments using four representative proteomes (RP) sets and the UniProtKB sequence database. More...

View options

We make a range of alignments for each Pfam-A family. You can see a description of each above. You can view these alignments in various ways but please note that some types of alignment are never generated while others may not be available for all families, most commonly because the alignments are too large to handle.

  Seed
(7)
Full
(4728)
Representative proteomes UniProt
(12897)
RP15
(329)
RP35
(1566)
RP55
(3433)
RP75
(6354)
Jalview View  View  View  View  View  View  View 
HTML View  View           
PP/heatmap 1 View           

1Cannot generate PP/Heatmap alignments for seeds; no PP data available

Key: ✓ available, x not generated, not available.

Format an alignment

  Seed
(7)
Full
(4728)
Representative proteomes UniProt
(12897)
RP15
(329)
RP35
(1566)
RP55
(3433)
RP75
(6354)
Alignment:
Format:
Order:
Sequence:
Gaps:
Download/view:

Download options

We make all of our alignments available in Stockholm format. You can download them here as raw, plain text files or as gzip-compressed files.

  Seed
(7)
Full
(4728)
Representative proteomes UniProt
(12897)
RP15
(329)
RP35
(1566)
RP55
(3433)
RP75
(6354)
Raw Stockholm Download   Download   Download   Download   Download   Download   Download  
Gzipped Download   Download   Download   Download   Download   Download   Download  

You can also download a FASTA format file containing the full-length sequences for all sequences in the full alignment.

HMM logo

HMM logos is one way of visualising profile HMMs. Logos provide a quick overview of the properties of an HMM in a graphical form. You can see a more detailed description of HMM logos and find out how you can interpret them here. More...

Trees

This page displays the phylogenetic tree for this family's seed alignment. We use FastTree to calculate neighbour join trees with a local bootstrap based on 100 resamples (shown next to the tree nodes). FastTree calculates approximately-maximum-likelihood phylogenetic trees from our seed alignment.

Note: You can also download the data file for the tree.

Curation and family details

This section shows the detailed information about the Pfam family. You can see the definitions of many of the terms in this section in the glossary and a fuller explanation of the scoring system that we use in the scores section of the help pages.

Curation View help on the curation process

Seed source: Manual
Previous IDs: none
Type: Family
Sequence Ontology: SO:0100021
Author: Studholme DJ
Number in seed: 7
Number in full: 4728
Average length of the domain: 401.9 aa
Average identity of full alignment: 26 %
Average coverage of the sequence by the domain: 79.14 %

HMM information View help on HMM parameters

HMM build commands:
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 61295632 -E 1000 --cpu 4 HMM pfamseq
Model details:
Parameter Sequence Domain
Gathering cut-off 29.8 29.8
Trusted cut-off 29.9 29.8
Noise cut-off 29.4 29.7
Model length: 469
Family (HMM) version: 14
Download: download the raw HMM for this family

Species distribution

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Archea Archea Eukaryota Eukaryota
Bacteria Bacteria Other sequences Other sequences
Viruses Viruses Unclassified Unclassified
Viroids Viroids Unclassified sequence Unclassified sequence

Selections

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This visualisation provides a simple graphical representation of the distribution of this family across species. You can find the original interactive tree in the adjacent tab. More...

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Please note: for large trees this can take some time. While the tree is loading, you can safely switch away from this tab but if you browse away from the family page entirely, the tree will not be loaded.

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe group, to allow us to map Pfam domains onto UniProt sequences and three-dimensional protein structures. The table below shows the structures on which the Tannase domain has been found. There are 49 instances of this domain found in the PDB. Note that there may be multiple copies of the domain in a single PDB structure, since many structures contain multiple copies of the same protein sequence.

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AlphaFold Structure Predictions

The list of proteins below match this family and have AlphaFold predicted structures. Click on the protein accession to view the predicted structure.

Protein Predicted structure External Information
A0A0D2DAG1 View 3D Structure Click here
A0A0D2DMY8 View 3D Structure Click here
A0A0D2E0T2 View 3D Structure Click here
A0A0D2GFJ0 View 3D Structure Click here
A0A0D2GGB2 View 3D Structure Click here
A0A0D2GTI9 View 3D Structure Click here
A0A0D2GWY5 View 3D Structure Click here
A0A0D2H3H7 View 3D Structure Click here
A0A0H3GL12 View 3D Structure Click here
A0A0K8P8E7 View 3D Structure Click here
A0A175VP87 View 3D Structure Click here
A0A175VSR3 View 3D Structure Click here
A0A175VTS0 View 3D Structure Click here
A0A175VUZ3 View 3D Structure Click here
A0A175W8T1 View 3D Structure Click here
A0A1C1CL11 View 3D Structure Click here
A0A1C1CL26 View 3D Structure Click here
A0A1C1CMG3 View 3D Structure Click here
A0A1C1D2I1 View 3D Structure Click here
A1CTK4 View 3D Structure Click here
A1DKV3 View 3D Structure Click here
A1DMV3 View 3D Structure Click here
A2R0Z6 View 3D Structure Click here
B8LV47 View 3D Structure Click here
B8NPA4 View 3D Structure Click here
B8NPT0 View 3D Structure Click here
D4AS70 View 3D Structure Click here
P78581 View 3D Structure Click here
Q0CI21 View 3D Structure Click here
Q0CVS2 View 3D Structure Click here
Q2UMX6 View 3D Structure Click here
Q2UP89 View 3D Structure Click here
Q4W8Z9 View 3D Structure Click here
Q4WMR0 View 3D Structure Click here
Q5BCF8 View 3D Structure Click here
Q8P8Y5 View 3D Structure Click here
Q8UK62 View 3D Structure Click here
U7PKX5 View 3D Structure Click here
U7PNB4 View 3D Structure Click here
U7PSC8 View 3D Structure Click here