# STOCKHOLM 1.0 #=GF ID RanGAP1_C #=GF AC PF07834.13 #=GF DE RanGAP1 C-terminal domain #=GF AU Fenech M;0000-0001-7933-4617 #=GF GA 25.0 25.0 #=GF NC 24.7 23.8 #=GF TC 26.0 25.2 #=GF SE Pfam-B_23411 (release 14.0) #=GF BM hmmbuild HMM.ann SEED.ann #=GF SM hmmsearch -Z 57096847 -E 1000 --cpu 4 HMM pfamseq #=GF TP Domain #=GF RN [1] #=GF RM 11853669 #=GF RT Structural basis for E2-mediated SUMO conjugation revealed by a #=GF RT complex between ubiquitin-conjugating enzyme Ubc9 and RanGAP1. #=GF RA Bernier-Villamor V, Sampson DA, Matunis MJ, Lima CD; #=GF RL Cell 2002;108:345-356. #=GF DR INTERPRO; IPR009109; #=GF DR SCOP; 1kps; sf; #=GF DR SO; 0000417; polypeptide_domain; #=GF CC Ran-GTPase activating protein 1 (RanGAP1, Swiss:P46061) is a #=GF CC GTPase activator for the nuclear Ras-related regulatory protein #=GF CC Ran, converting it to the putatively inactive GDP-bound state. #=GF CC Its C-terminal domain is required for RanGAP1 localisation at #=GF CC the vertebrate nuclear pore complex, and is sumoylated by the #=GF CC small ubiquitin-related modifier protein (SUMO-1, Swiss:Q93068). #=GF CC This domain is composed almost entirely of helical substructures #=GF CC that are organised into an alpha-alpha superhelix fold, with the #=GF CC exception of the peptide containing the lysine residue required #=GF CC for SUMO-1 conjugation [1]. #=GF SQ 74 M7BXE8.1/425-512 -QESLPSKKILDSHDSTPVS.......PPP.pPVDVATFLAFPSPE..KLLRL..G.........P..KC..SV.LIAQQT.....DT...SD...T.......E.....K.......VVMAL....L....KI....SS.V.FK..D............E..-.....TTVKT........AVHETTG--------....-----.---.--..-.---.-------...----..---.--.-------.-----..---.-----------------..---------.----------- M7BXE8.1/514-639 --------------------.......---..--------------..-----..-.........-..--..--.----AT.....DT...SD...T.......E.....K.......VVMAL....L....KI....SS.V.FK..D............E..-.....TTVKT........AVHETTDALMRKAFI....SATFN.SDA.FI..T.SLL.IHMGLLK...SEEK..IKA.VP.SLYGPLM.TLNHM..VQQ.DYFPKSLAPVLLAFVTK..PNRALDSCS.FARRMLLQTLH Q08BV5.1/386-564 EEEEEEEEKTELNQFSTPPS.......APR..TPDVSSFLSFPSPD..KLLRL..G.........E..KR..SV.LIQQQV.....DV...LD...V.......C.....K.......TAEAF....L....KI....SS.V.YK..D............N..D.....AEVKS........AVLESIDAVLSKAFF....TPSFQ.GLA.FV..S.SLL.VMVGLLK...SEDK..LKP.VK.VVPGHLL.CLEHA..VKQ.SYFPREHITVLNAFMSR..PNKSLEVCS.SARDRLKNTLQ F1NIE8.1/402-577 -QDSMTPKKIIGSQDSTPVP.......SP-..PVDVATFLAFPSPE..KLLRL..G.........P..KC..SV.LIAQQT.....DT...SD...V.......E.....K.......VVTAL....L....RI....SS.V.FK..D............E..-.....AQVKT........AVHETADALMKKAFS....SATFN.SDA.FI..T.RLL.IHMGLLK...SEEK..IKA.VP.SLYGILM.TLNHM..VQQ.DYFPKSLAPVLSAFVTK..PNRALDSCS.FARHMLLQTLH A0A2I0USI2.1/409-584 -QESLTPKKIINSQDSTPVP.......SP-..PVDVATFLAFPSPE..KLLRL..G.........S..KC..SV.LIAQQT.....DT...SD...V.......E.....K.......VVTTL....L....RI....SS.V.FK..D............D..-.....ASVKT........AVHETTDALMRKAFT....SATFN.SDA.FI..T.SLL.IHMGLLK...SEEK..IKA.VP.SLYGILM.TLNHV..VQQ.DYFPKSLAPVLSAFVTK..PNRALDSCS.FARHMLLQTLH A0A2F0AY42.1/475-655 EESTTPPRKILDPNSGEPAPv....lsSPP..PADVSTFLAFPSPE..KLLRL..G.........P..KS..SV.LIAQQT.....DT...SD...P.......E.....K.......VVSAF....L....KV....SS.V.FK..D............E..-.....ATVRS........AVQDAVDTLMKKAFS....SSSFN.SNA.FL..T.RLL.IHMGLLK...SEDK..IKA.IA.NLYGPLM.ALNHM..VQQ.EYFPKALAPLLLAFVTK..PNGALESCS.FARHNLLQTLY P46060.1/409-585 ----TPSRKILDPNTGEPAPv....lsSPP..PADVSTFLAFPSPE..KLLRL..G.........P..KS..SV.LIAQQT.....DT...SD...P.......E.....K.......VVSAF....L....KV....SS.V.FK..D............E..-.....ATVRM........AVQDAVDALMQKAFN....SSSFN.SNT.FL..T.RLL.VHMGLLK...SEDK..VKA.IA.NLYGPLM.ALNHM..VQQ.DYFPKALAPLLLAFVTK..PNSALESCS.FARHSLLQTLY F1MAA5.2/410-584 ------SRKILDPNSGEPAPv....lsSPP..PTDLSTFLSFPSPE..KLLRL..G.........P..KV..SV.LIVQQT.....DT...SD...P.......E.....K.......VVSAF....L....KV....AS.V.FR..D............E..-.....ASVKT........AVLDAIDALMKKAFS....SSSFN.SNT.FL..T.RLL.IHMGLLK...SEDK..IKA.IP.SLHGPLM.VLNHV..VQQ.DYFPKTLAPLLLAFVTK..PNGALESCS.FARHSLLQTLY P46061.2/413-587 ------SRKILDPNSGEPAPv....lsSPT..PTDLSTFLSFPSPE..KLLRL..G.........P..KV..SV.LIVQQT.....DT...SD...P.......E.....K.......VVSAF....L....KV....AS.V.FR..D............D..-.....ASVKT........AVLDAIDALMKKAFS....CSSFN.SNT.FL..T.RLL.IHMGLLK...SEDK..IKA.IP.SLHGPLM.VLNHV..VRQ.DYFPKALAPLLLAFVTK..PNGALETCS.FARHNLLQTLY A9JTA8.1/396-570 ----ENGLNGTKDVIEEKEE.......PPH..SSELMSFLVSPSAE..KLISL..G.........A..KR..VQ.LIEQQV.....DV...TD...A.......N.....K.......VSEVF....L....KI....SS.V.YK..D............E..-.....PEVKQ........AVFETTDALLRKAFS...nSPHSQ.SYS.FI..S.SLM.VNLGLLK...SEDK.kVKK.VS.VLPGHLL.TLEHA..VSQ.EFFPADQAGVLESFVSR..NGAVLESCC.SARDALKITL- A0A2R8QT01.1/398-572 ----ENGLNGTKDVIEEKEE.......PPH..SSELMSFLVSPSAE..KLISL..G.........A..KR..VQ.LIEQQV.....DV...TD...A.......N.....K.......VSEVF....L....KI....SS.V.YK..D............E..-.....PEVKQ........AVFETTDALLRKAFS...nSPHSQ.SYS.FI..S.SLM.VNLGLLK...SEDK.kVKK.VS.VLPGHLL.TLEHA..VSQ.EFFPADQAGVLESFVSR..NGAVLESCC.SARDALKITL- W4X9X4.1/170-353 QESKDPHLQVKGTAISPRREe.....tKYM.iPVTAADFLAFPTAN..KLQAL..G.........N..QR..AE.KILQELg...dEV...YE...E.......S.....A.......GIKAF....V....KI....SS.V.ME..S............E..N.....NDVKN........AVYQCTDAILKKLFS....SEKCT.PES.VV..N.ALL.VHLGLIK...GEDK..LRP.VG.DPSGMLL.TLGHA..VKQ.QYYPKSTAPIFMTFLSR..PNSKIDDCV.SAKHGLMQAIY A0A3M0JQU3.1/370-526 -QESLTPKKILDSQASTPVP.......SP-..PVDVATFLAFPSPE..KLLRL..G.........P..KC..SV.LIAQQT.....DT...SD...V.......E.....K.......VVATL....L....RI....SS.V.FK..D............E..-.....ASVKA........AVHETADALMKKAFS....SATFN.SDA.FI..T.NLL.VHMGLLK...SEEK..IKT.VP.SLYGILM.TLNHM..VQQ.DYFPKSLVPVLTAFVTK..K--------.----------- A0A2P4TIG4.1/383-538 -QDTMTPKKIIGSQDSTSVP.......SP-..PVDVATFLAFPSPE..KLLRL..G.........P..KC..SV.LIAQQT.....DT...SD...V.......E.....K.......VVTAL....L....RI....SS.V.FK..D............E..-.....AQVKT........AVHETTDALMKKAFS....SATFN.SDA.FI..T.RLL.IHMGLLK...SEEK..IKA.VP.SLYGILM.TLNHM..VQQ.DYFPKSLAPVLSAFVTK..---------.----------- A0A091QH23.1/399-551 ----LTSKKIIDSQDSSPVP.......SP-..PVDIATFLAFPSPE..KLLRL..G.........P..KC..PV.LIAQQV.....DI...SD...V.......E.....K.......VVTTL....L....RV....SS.L.FK..D............D..-.....AAVKT........AVQDTTDALMRKAFT....SATFN.SDA.FV..T.SLL.IHMGLLK...SEEK..IKA.VP.SLYGILM.TLNHM..VQQ.DYFPKSLVPVLLAFVTK..---------.----------- K1RBZ5.1/337-515 EEVNDPELQVKGKSISPNKK.......---..-VTAKDFLAFPSPS..KLLQL..G.........S..GR..AQ.ALKEELg...aDV...ND...L.......E.....K.......AVQAF....M....KI....SS.V.VT..M............E..D.....TKAKE........AACDCADQIIEEAVK...cNREND.AVL.LA..N.TIL.VYIGVLK...GEDK.sYKP.PN.SVTGPLL.VLEHI..VRQ.PYFPKFSREMLQAFCSK..PHPLLDSTP.QARHKLLQTLY S4R4J8.1/471-632 ----------------KPSE.......VAA..RPDASAFLTFPSPE..KLVSL..G.........P..QR..SA.LLLQSVe...eDV...HN...P.......D.....K.......VVETF....L....KL....SS.V.YK..P............E..-.....TVVQC........AVFESADALLQRAFQ....MANFQ.-QA.FM..S.SLL.IHLGLIK...SEEK..VKP.VS.NLQGPLA.TLEHV..VKQ.QYFPRSLLPILKVFMSK..TNKILEQCE.PARNSLLQTL- A0A401P4B7.1/417-584 ------------LIVEEPVKt....lpIAP..TSEAAVFLASPSPD..KLIKL..G.........S..KR..AL.LILQQT.....DL...SN...A.......E.....K.......VVQTF....L....KV....AT.A.YR..E............D..-.....QETKT........AVLDTADELLQKAFQ....IPEFP.FDV.FI..T.TLL.VYMGLLK...SEEK..IKV.VA.NLIGPLT.ILKQV..IQK.SYFPRSVIPILSAFLNK..QNRAFDSCL.NAKYTLLETM- A0A6J8DJ50.1/361-534 ----DPELQVKGKGITPKKQ.......---..AVSAKDFLAFPSPQ..KLKQM..G.........R..QK..AD.NLAQELg...nEI...TD...L.......D.....K.......VVQTF....L....RI....SS.I.VT..T............D..D.....VDTKE........SVCECAEKLIEETLK....SEHNT.GSM.LA..N.SIL.VSMGILK...GEDK.kYKP.PS.TLMGPLL.VLEHL..VKQ.PFFPKFSREILSMFMSK..PHPLLEKSK.EARHKLLQTL- A0A4Z2GDW0.1/399-564 -----------TRKDDSPAK.......PPS..PAEVTTFLSCPSAE..RLLQL..G.........E..MR..TS.-LQQQV.....DA...AD...P.......H.....R.......AADVL....L....KI....AS.L.YS..E............D..-.....PETKA........AVLETVDGVLEKLLS....GSAFQ.SYR.FL..S.SLL.VMMGLLK...GEGK..MKK.VT.LVPGQLL.CLEHA..IQQ.EYFLQQHAALLHTFVSR..NSGALESCS.SASERLSSTLE A0A210PLC4.1/391-566 ---DDPELQVKGKAISPEKQ.......---..SVSAKDFLAFPSPT..KLIQL..G.........T..GR..AA.ALKQELg...sDC...SD...V.......D.....K.......AVQTF....I....KV....SS.V.VT..P............V..D.....TKTKE........AACDCTDKLFEDLLL...dSTEGG.ASL.FA..N.SLL.VNMGVLK...GEDK.kFRP.PS.SIVGPLT.VLEYA..VKQ.PYFPKQSREILSAFITK..PHPLLDKSG.PARHNLLQTL- A0A1S3IY57.1/394-572 ---CDPNLQVKGTAISPRPE.......DMK..PVSVTEFLQLPTAP..KLISL..G.........S..DR..TA.KIMTEIe...kDF...NN...T.......D.....K.......CIQTL....M....KI....SC.V.VS..S............E..N.....TKAQN........AVNEIADSLLGKLLR...gTDEST.KAT.IS..N.SIL.VHIGLLK...SEDK..VKP.VA.DPSGPML.VLSHV..VKQ.SYFPKLARDILQVFFGR..PHERLDKCQ.QSKHLLLQSLY A0A1S3IXJ3.1/394-572 ---CDPNLQVKGTAISPRPE.......DMK..PVSVTEFLQLPTAP..KLISL..G.........S..DR..TA.KIMTEIe...kDF...NN...T.......D.....K.......CIQTL....M....KI....SC.V.VS..S............E..N.....TKAQN........AVNEIADSLLGKLLR...gTDEST.KAT.IS..N.SIL.VHIGLLK...SEDK..VKP.VA.DPSGPML.VLSHV..VKQ.SYFPKLARDILQVFFGR..PHERLDKCQ.QSKHLLLQSLY A0A3S0ZLL5.1/393-566 ----DPKLQVKGSAVTPSK-.......--Q..IVSVKDFLAFPSPS..KLLQL..G.........K..SG..GE.ALLQELg...pDK...DD...V.......E.....K.......IISMI....M....KV....AI.V.VN..K............D..-.....GDAKV........KACECADTLLKHGLS....TSDNA.GIL.VA..N.AFL.VAMGLLK...GEDK.kLKT.PS.SITGPLL.ILEHI..VRQ.SYFPKIGREILLVFLSK..PHPMLEKSA.DARHRMLQTLH V8P5X7.1/385-458 ----LTPKKILEEHDSTPLS.......SPL.pPVDVGTFLAFPSPE..KLLRL..G.........P..KC..ST.LIMQQT.....DT...SD...T.......E.....K.......VVTVF....L....KI....SS.V.FK..D............E..T.....-----........---------------....-----.---.--..-.---.-------...----..---.--.-------.-----..---.-----------------..---------.----------- V8P5X7.1/460-520 --------------------.......---..--------------..-----..-.........-..--..--.------.....--...--...-.......-.....-.......-----....-....--....--.-.--..-............-..-.....-----........---------------....-----.---.--..-.---.-------...SEEK..IRA.VP.SLYGPLM.TLEHM..VQQ.NYFPKSLAPILLAFVTK..PNGALDSCS.FARHSLLQTLH A0A0L8HEA2.1/419-592 -----------SLKASELMK......tPPH..KVSARDFLAFPSPS..KLLQM..G.........T..ADtiTK.NIKAELg...eSC...TN...V.......D.....E.......VVKTF....L....KI....AS.V.VD..S............Q..N.....EKLKK........TANQCTDSLFSELLK...aNPEEN.TSL.LF..N.SLL.VHMGLLK...GEDK.kYKS.PG.DLNGTLI.VLEHC..VQQ.AYFPSFGRDILSAFISR..PSTMLENCS.EMQHKFLQTV- T1IIM9.1/393-566 ----------TNSDITAKHD.......VPS.iPVTAKEFLESPTAE..KFLAL..G.........D..DR..SC.LIMEEI....nND...LD...F.......D.....R.......RISTV....L....KL....SS.C.VS..L............D..N.....EEVKD........AAFECADALLMEVFE...lAEKQD.RLSvLS..N.SLL.VQLGLIK...SEDK.tFKP.MT.DLTGPLI.VLEHV..VRQ.PYFSRITKEILQLFLSR..PNKAIDACG.SVKHKWLQTLY A0A2T7PLL9.1/407-582 --NEDPELQVKGKAITPSK-.......---..QVSAEDFLSFPSPS..KLQQL..G.........F..DK..VE.AMKKAIg...tDI...ND...P.......N.....R.......LVETV....I....KV....SL.I.VS..E............D..D.....AKTMK........AACECADGLLKHAFD....NIENA.ASV.IP..N.AFL.VFLGLLK...SEDK.kYKA.PS.SITGPLL.VLSHI..VKQ.TYFPKSARDTFQFFFSR..PHPQLEKSS.TARHKILESLY V3ZN44.1/388-564 EEVNDPELQVKGQSLTPQK-.......---..KVTAGDFLAFPSPT..KLQHL..G.........D..NK..GE.AIKAELg...nES...ND...I.......E.....K.......VVDTI....F....RI....SS.I.VT..E............S..D.....VTTKT........TACQCADELLKSIVK....-DESE.SSL.FT..N.LYL.VKLGLIK...GEDK.kYRP.PT.DVSGPLL.VLTHI..IQQ.EYIAHISREILQIFIAK..THPVLDKAQ.SARHQLLQTLY T1IT55.1/192-365 ----------TNSDITAKHD.......VPS.iPVTAKEFLESPTAE..KFLAL..G.........D..DR..SC.LIMEEI....nND...LD...F.......D.....R.......RISTV....L....KL....FS.C.VS..L............D..N.....EEVKD........AAFECADAHLMEVFE...lAEKQD.CLSvLS..N.SLL.VQLGLIK...SEDK.tFKP.MT.DLTGPLI.VLEHV..VSQ.PYFSRIKKEILQLFLSR..PNKAIDACG.SVKHKWLQTLY C3YQ97.1/125-290 ----DPELQVRGTAITPTREn.....qSPLkvSYTAQEFLDSPSAD..RLLGL..G.........K..ER..AQ.LLVKELgtglySL...DD...A.......D.....C.......AASSL....M....KV....AS.I.VT..D............D..-.....TAVKS........AAFQCADAILTRSLQ....SEESQ.PTL.IA..N.GLL.VHMGLLK...SEEK..VQP.IS.DLQGPLI.LLQHI..FQQ.VYFPRSLAQLFIAFLTR..SRQ------.----------- R7URF9.1/3-156 --------------------.......---..--TVDEFLKRPSAS..SLLLL..G.........P..QR..SD.LICKQI.....YK...DD...L.......N.....E.......VARTV....M....KI....SM.I.LT..E............G..N.....EAANK........AAFECTDELLKEALP....GDDTV.TAA.FC..N.ECL.VQLGLLK...AEDK.kLTL.VL.NSSGPLI.MLTHI..VKQ.SYFSKMGKDILQIFIAK..PNAKLDAYA.DLKHKLLQAL- R7UC73.1/401-563 ----------------TPRP.......DEK..TITVDEFLKRPSAS..SLLLL..G.........P..QR..SD.LICKQI.....YK...DD...L.......N.....E.......VARTV....I....KI....SM.I.LT..E............G..N.....EAANK........AAFECTDELLKEALP....GDDTV.TAA.FC..N.ECL.VQLGLLK...AEDK.kLTL.VL.NSSGPLI.MLTHI..VKQ.SYFSKMGKDILQIFIAK..PNAKLDAYA.DLKHKLLQAL- A0A1S3KGS4.1/5-132 --------------------.......---..--------------..-----..-.........-..--..--.----EK.....DL...NN...T.......D.....K.......CIQTL....M....KI....SC.V.VS..S............E..N.....TKAQN........AVNEIADSLLGKLLH...gTDERT.MAT.IS..N.SIL.VHIGLLK...SEDK..VKP.VA.DPSGPML.VLSHV..VKQ.SYFPKLARDILQVFFGR..PHERLDKCQ.QSKHLLLQSLY A0A0L8HDE7.1/435-559 --------------------.......---..--------------..-----..-.........-..--..--.------.....-C...TN...V.......D.....E.......VVKTF....L....KI....AS.V.VD..S............Q..N.....EKLKK........TANQCTDSLFSELLK...aNPEEN.TSL.LF..N.SLL.VHMGLLK...GEDK.kYKS.PG.DLNGTLI.VLEHC..VQQ.AYFPSFGRDILSAFISR..PSTMLENCS.EMQHKFLQTV- A0A2J7PHG2.1/424-604 ----DVKLNDNQATGHKPVE.......DTR..VVSVPEFLQHPTQE..HFLLL..G.........N..NR..LE.LIMKEI....kDC...NDdsyL.......E.....K.......LVMTL....M....KV....SS.L.TA..N............S..S.....EQTKQ........AALSCSDALYRELFKw..aEEHEQ.SSI.AN..N.SLL.VHLGLIK...SEDK.kMKL.AW.NLDGCMG.ALEQA..IKQ.DYFPQGTRETLQLFLRR..PNLSMDAFP.ATKHKLMSTL- A0A2B4RA88.1/378-530 --------------------.......---..--VVQDFFKSPTLE..KFKNI..P........sS..QR..RS.LLAEYLk...dDL...YE...T.......N.....K.......VAKYF....V....SI....SV.A.LK..N............D..-.....---KD........ALMEWADTVLKPSLE....SADCK.EEG.LI..S.SLL.IHMGLLK...GEEK..MEY.PK.DISGPLK.ALDYT..VKQ.PYFPRHLKSFFVAFVSK..PNKLLESCL.ETRHQFLQTLY A0A2B4SZF1.1/509-611 --------------------.......---..--------------..-----..-.........-..--..--.------.....--...-D...A.......D.....K.......IAKIF....L....HV....CV.A.FV..S............D..-.....---QR........LLFSCAGAVLKLGLC....HSQSN.AVA.LG..T.CIL.VRMGLLK...QEDY..VDI.VK.DLTGPLL.ALEHL..CAE.EYFPRNLAAIFASFLSK..SSPRL----.----------- A0A2B4SZF1.1/644-746 --------------------.......---..--------------..-----..-.........-..--..--.------.....--...--...-.......-.....-.......--KNF....K....RV....CD.I.VA..L............E..-.....-GYRE........ELLSCVDALFSRAFV....TLGCN.AWR.IG..E.SIL.IYLGLLK...GELH..VET.VR.NHSSALK.LLLHV..LKQ.SYCPPILKQLLVCFLQK..PNPLLTSYS.----------- A0A2P8YZK8.1/416-588 --------------KHMTDV.......GPN..TITVAEFCQNPTPE..RFLAL..G.........S..NR..LD.LIRNDIks.cpED...SY...V.......E.....K.......LMPLL....M....KV....SS.L.CA..S............N..S.....KVVK-........PALACSDAIYRDLFK...wSEKHN.KMS.LV..NnMLL.VHLGLIK...SEDK.gMKL.SW.NLDGCLL.SLEHA..IKQ.DYFPQGTRETLQLFLGRqvPCQTMGALS.ASKHKLMSTLY A0A2J7PHG4.1/424-591 ----DVKLNDNQATGHKPVE.......DTR..VVSVPEFLQHPTQE..HFLLL..G.........N..NR..LE.LIMKEI....kDC...NDdsyL.......E.....K.......LVMTL....M....KV....SS.L.TA..N............S..S.....EQTKQ........AALSCSDALYRELFKw..aEEHEQ.SSI.AN..N.SLL.VHLGLIK...SEDK.kMKL.AW.NLDGCMG.ALEQA..IKQ.DYFPQGTRETLQLFLRR..QVIDVE---.----------- A0A6A4WQ15.1/317-496 -------KREEAAAAKRPGI.......TPI..QCTVAEFLCQPTAA..RLLGL..G.........D..QR..QQ.LLTKEAln.vkEI...GD..gR.......C.....A.......AVQRH....L....QL...lSA.V.CR..V............DasQ.....PPVDQ........LLPPLVDALLRSALD....TAGED.LGL.LS..N.SLL.VYLGLIK...CEDK..QFS.VSwDVKGMLV.ALTRA..VRQ.PYFPATVRDTLQTFLSR..PNKTVDMHP.QQKHLLMQAL- A0A6J1TM62.1/387-556 EEEEDEENDDSNDTVEVPLN.......LPN.eQCTVRQFLETPTGE..RLVSV..T.........T..DK..LL.QEAKYL....aDE...NY...L.......E.....N.......LLPML....M....KV....AA.L.SS..H............S..N.....SKVQQ........VALKTSEELLRHMYSwakkGDSFR.SAL.TN..N.ALL.VHLGLIK...SEDK.aLKV.TW.NLDGCLV.ALEHS..IKQ.NVFPDSTLHLLRFFLER..PNSL-----.----------- A0A0T6BDU8.1/408-570 -----NHTKDEVQIFENL-Sl.....sENK..TVNVMDFLSKPNPD..NFLAL..G.........S..NV..SS.LLLAEA.....DEntgNN...I.......E.....K.......LTEIL....M....KV....GS.LnVA..M............K..G.....EENIQ........SVLKCTELLFKELFT....HAQNS.DNL.SImnN.CLL.VYLGLIK...SEDK.kFKP.TW.NIDGCLI.ALHNV..VKK.NYVPESTKNTLKVFMQK..E--------.----------- A0A3R7PR40.1/343-509 --------------------.......-PV..KCTAEEFCEQPTAA..RLLGL..G.........N..SG.pSQ.LVEEAK.....RL...AEg.sE.......E.....A.......LINFC....L....KIlmrtGS.I.AT..S............N..N.....AEVQK........AVNAATEQLAKAAFA...aAQKSD.SLS.LA.tN.SLL.VHLGLIK...CEDK.kFKL.EW.DLKGCLI.ALATI..VSS.PLFPEQTKSTLQLFLSK..PNPKIDVHN.QEKHKLMVAL- A0A2G9NB44.1/1-61 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