Summary: Albumin I chain b
Albumin I chain b Provide feedback
The albumin I protein, a hormone-like peptide, stimulates kinase activity upon binding a membrane bound 43 kDa receptor. The structure of this domain (chain b) reveals a knottin like fold, comprise of three beta strands .
Yamazaki T, Takaoka M, Katoh E, Hanada K, Sakita M, Sakata K, Nishiuchi Y, Hirano H; , Eur J Biochem 2003;270:1269-1276.: A possible physiological function and the tertiary structure of a 4-kDa peptide in legumes. PUBMED:12631285 EPMC:12631285
External database links
This tab holds annotation information from the InterPro database.
InterPro entry IPR012512
The albumin I protein, a hormone-like peptide, stimulates kinase activity upon binding a membrane bound 43 kDa receptor. The structure of this region reveals a knottin like fold, comprise of three beta strands [PUBMED:12631285].
The mapping between Pfam and Gene Ontology is provided by InterPro. If you use this data please cite InterPro.
|Molecular function||nutrient reservoir activity (GO:0045735)|
|Biological process||pathogenesis (GO:0009405)|
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This clan contains a set of related small protein toxins and what appears to be the functionally distinct Albumin I domain. All members of this clan have a knottin-like fold. Additional information about this clan may be found from .
The clan contains the following 22 members:Agouti Albumin_I Albumin_I_a Chi-conotoxin Conotoxin Mu-conotoxin Omega-toxin Tachystatin_A Tachystatin_B Toxin_11 Toxin_12 Toxin_16 Toxin_18 Toxin_21 Toxin_22 Toxin_23 Toxin_24 Toxin_27 Toxin_30 Toxin_7 Toxin_9 UPF0506
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Curation and family details
|Seed source:||Pfam-B_100627 (release 16.0)|
|Author:||Finn RD, Bateman A|
|Number in seed:||2|
|Number in full:||69|
|Average length of the domain:||33.70 aa|
|Average identity of full alignment:||62 %|
|Average coverage of the sequence by the domain:||28.19 %|
|HMM build commands:||
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 80369284 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||7|
|Download:||download the raw HMM for this family|
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For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe group, to allow us to map Pfam domains onto UniProt sequences and three-dimensional protein structures. The table below shows the structures on which the Albumin_I domain has been found. There are 2 instances of this domain found in the PDB. Note that there may be multiple copies of the domain in a single PDB structure, since many structures contain multiple copies of the same protein seqence.
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