Summary: B melanoma antigen family
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B melanoma antigen family Provide feedback
This family consists of the B melanoma antigen (BAGE) peptides. The BAGE gene encodes a human tumour antigen that is recognised by a cytolytic T lymphocyte. BAGE genes are expressed in melanomas, bladder and lung carcinomas and in a few tumours of other histological types .
Ruault M, van der Bruggen P, Brun ME, Boyle S, Roizes G, De Sario A; , Eur J Hum Genet 2002;10:833-840.: New BAGE (B melanoma antigen) genes mapping to the juxtacentromeric regions of human chromosomes 13 and 21 have a cancer/testis expression profile. PUBMED:12461691 EPMC:12461691
External database links
This tab holds annotation information from the InterPro database.
InterPro entry IPR012530
This family consists of the B melanoma antigen (BAGE) peptides. The BAGE gene encodes a human tumour antigen that is recognised by a cytolytic T lymphocyte. BAGE genes are expressed in melanomas, bladder and lung carcinomas and in a few tumours of other histological types [PUBMED:12461691].
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Curation and family details
|Seed source:||Short protein clustering|
|Number in seed:||5|
|Number in full:||119|
|Average length of the domain:||28.70 aa|
|Average identity of full alignment:||74 %|
|Average coverage of the sequence by the domain:||4.85 %|
|HMM build commands:||
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||6|
|Download:||download the raw HMM for this family|
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