Summary: Insect kinin peptide
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These neuropeptides are the first members of the insect kinin-family isolated from the American cockroach. Their occurrence in the retrocerebral complex suggests a physiological role as a neurohormone. The C-terminal sequence Phe-X-Ser-Trp-Gly-NH2 characterised the peptides as members of the insect kinin family. Data suggest a possible involvement of insect kinins in water-balance by regulating the osmoregulation. These peptides have length from 6 to 14 amino acids .
Predel R, Kellner R, Rapus J, Penzlin H, Gade G; , Regul Pept 1997;71:199-205.: Isolation and structural elucidation of eight kinins from the retrocerebral complex of the American cockroach, Periplaneta americana. PUBMED:9350979 EPMC:9350979
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This tab holds annotation information from the InterPro database.
InterPro entry IPR013202
This entry represents neuropeptides that are the first members of the insect kinin-family isolated from the American cockroach. Their occurrence in the retrocerebral complex suggests a physiological role as a neurohormone. The C-terminal sequence Phe-X-Ser-Trp-Gly-NH2 characterised the peptides as members of the insect kinin family. Data suggest a possible involvement of insect kinins in water-balance by regulating the osmoregulation. Insect kinins also mediate visceral muscle contractile activity (myotropic activity) [PUBMED:9350979]. These peptides have lengths ranging from 6 to 14 amino acids [PUBMED:9350979].
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Curation and family details
|Seed source:||Short protein clustering|
|Number in seed:||3|
|Number in full:||5|
|Average length of the domain:||8.00 aa|
|Average identity of full alignment:||79 %|
|Average coverage of the sequence by the domain:||100.00 %|
|HMM build commands:||
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||6|
|Download:||download the raw HMM for this family|
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