Summary: Spc7 kinetochore protein
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Spc7 kinetochore protein Provide feedback
This domain is found in cell division proteins which are required for kinetochore-spindle association .
Kerres A, Vietmeier-Decker C, Ortiz J, Karig I, Beuter C, Hegemann J, Lechner J, Fleig U; , Mol Biol Cell 2004;15:5255-5267.: The fission yeast kinetochore component Spc7 associates with the EB1 family member Mal3 and is required for kinetochore-spindle association. PUBMED:15371542 EPMC:15371542
External database links
This tab holds annotation information from the InterPro database.
InterPro entry IPR013253
This domain is found in cell division proteins which are required for kinetochore-spindle association [PUBMED:15371542]. Proteins contain this domain include budding yeast Spc105 and fission yeast Spc7.
Spc7 is a component of the NMS (Ndc80-MIND-Spc7) super complex, which has a role in kinetochore function during late meiotic prophase and throughout the mitotic cell cycle [PUBMED:22711988]. Spc105 and Kre28 forms a kinetochore complex, which is required for kinetochore binding by a discrete subset of kMAPs (BIM1, BIK1 and SLK19) and motors (CIN8, KAR3) [PUBMED:19893618].
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Curation and family details
|Author:||Mistry J, Wood V|
|Number in seed:||58|
|Number in full:||308|
|Average length of the domain:||299.30 aa|
|Average identity of full alignment:||27 %|
|Average coverage of the sequence by the domain:||24.89 %|
|HMM build commands:||
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 80369284 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||7|
|Download:||download the raw HMM for this family|
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