Summary: Lipoprotein GNA1870 C terminal like
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Lipoprotein GNA1870 C terminal like Provide feedback
GNA1870 is a surface exposed lipoprotein in Neisseria meningitidis that and is a potent antigen of Meningococcus. The structure of the C terminal domain consists of an anti-parallel beta barrel overlaid by a short alpha helical region .
Cantini F, Savino S, Scarselli M, Masignani V, Pizza M, Romagnoli G, Swennen E, Veggi D, Banci L, Rappuoli R; , J Biol Chem. 2006;281:7220-7227.: Solution structure of the immunodominant domain of protective antigen GNA1870 of Neisseria meningitidis. PUBMED:16407174 EPMC:16407174
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This tab holds annotation information from the InterPro database.
InterPro entry IPR014902
GNA1870 is a surface exposed lipoprotein in Neisseria meningitidis that is a potent antigen and a potential candidate for a vaccine against meningococcal disease. The structure of the C-terminal domain consists of an anti-parallel beta barrel overlaid by a short alpha helical region [PUBMED:16407174].
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Curation and family details
|Number in seed:||2|
|Number in full:||580|
|Average length of the domain:||148.80 aa|
|Average identity of full alignment:||63 %|
|Average coverage of the sequence by the domain:||58.36 %|
|HMM build commands:||
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||5|
|Download:||download the raw HMM for this family|
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For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe group, to allow us to map Pfam domains onto UniProt sequences and three-dimensional protein structures. The table below shows the structures on which the Lipoprot_C domain has been found. There are 13 instances of this domain found in the PDB. Note that there may be multiple copies of the domain in a single PDB structure, since many structures contain multiple copies of the same protein seqence.
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