Summary: Protein of unknown function (DUF2029)
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Domain of unknown function Edit Wikipedia article
Frequency and conservation
Role in biology
Essential DUFs (eDUFs)
Protein of unknown function (DUF2029) Provide feedback
This is a putative transmembrane protein from bacteria. It is likely to be conserved between Mycobacterium species .
Cole ST, Eiglmeier K, Parkhill J, James KD, Thomson NR, Wheeler PR, Honore N, Garnier T, Churcher C, Harris D, Mungall K, Basham D, Brown D, Chillingworth T, Connor R, Davies RM, Devlin K, Duthoy S, Feltwell T, Fraser A, Hamlin N, Holroyd S, Hornsby T, Ja, Nature. 2001;409:1007-1011.: Massive gene decay in the leprosy bacillus. PUBMED:11234002 EPMC:11234002
This tab holds annotation information from the InterPro database.
InterPro entry IPR018584
This is a putative transmembrane protein from prokaryotes. It is likely to be conserved between Mycobacterium species [PUBMED:11234002].
The mapping between Pfam and Gene Ontology is provided by InterPro. If you use this data please cite InterPro.
|Molecular function||transferase activity, transferring hexosyl groups (GO:0016758)|
- the number of sequences which exhibit this architecture
a textual description of the architecture, e.g. Gla, EGF x 2, Trypsin.
This example describes an architecture with one
Gladomain, followed by two consecutive
EGFdomains, and finally a single
- the UniProt description of the protein sequence
- the number of residues in the sequence
- the Pfam graphic itself.
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This is the GT-C clan that contains diverse glycosyltransferases that possess 8-13 predicted transmembrane segments .
The clan contains the following 19 members:ALG3 Alg6_Alg8 Arabinose_trans DIE2_ALG10 DUF2029 DUF2079 DUF2142 DUF2723 EpsG Glucan_synthase Glyco_transf_22 Mannosyl_trans Mannosyl_trans2 PIG-U PMT PMT_2 PTPS_related STT3 YfhO
We make a range of alignments for each Pfam-A family:
- the curated alignment from which the HMM for the family is built
- the alignment generated by searching the sequence database using the HMM
- Representative Proteomes (RPs) at 15%, 35%, 55% and 75% co-membership thresholds
- alignment generated by searching the UniProtKB sequence database using the family HMM
- alignment generated by searching the NCBI sequence database using the family HMM
- alignment generated by searching the metagenomics sequence database using the family HMM
You can see the alignments as HTML or in three different sequence viewers:
1Cannot generate PP/Heatmap alignments for seeds; no PP data available
Key: available, not generated, — not available.
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Curation and family details
|Seed source:||Pfam-B_1780 (release 21.0)|
|Number in seed:||95|
|Number in full:||966|
|Average length of the domain:||239.50 aa|
|Average identity of full alignment:||17 %|
|Average coverage of the sequence by the domain:||51.95 %|
|HMM build commands:||
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 11927849 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||7|
|Download:||download the raw HMM for this family|
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How the sunburst is generated
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The tree shows the occurrence of this domain across different species. More...
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