Summary: Putative addiction module component
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This entry defines several short bacterial proteins, typically about 75 amino acids long, which are always found as part of a pair (at least) of small genes. The other protein in the pair always belongs to a family of plasmid stabilisation proteins (IPR007712). It is likely that this protein and its partner comprise some form of addiction module - a pair of genes consisting of a stable toxin and an unstable antitoxin which mediate programmed cell death - although these gene-pairs are usually found on the bacterial main chromosome.
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This tab holds annotation information from the InterPro database.
InterPro entry IPR013406
This entry defines several short bacterial proteins, typically about 75 amino acids long, which are always found as part of a pair (at least) of small genes. The other protein in the pair always belongs to a family of plasmid stabilisation proteins (INTERPRO). It is likely that this protein and its partner comprise some form of addiction module - a pair of genes consisting of a stable toxin and an unstable antitoxin which mediate programmed cell death [PUBMED:10547685] - although these gene pairs are usually found on the bacterial main chromosome.
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Curation and family details
|Author:||TIGRFAMs, Coggill P|
|Number in seed:||160|
|Number in full:||600|
|Average length of the domain:||52.80 aa|
|Average identity of full alignment:||24 %|
|Average coverage of the sequence by the domain:||69.97 %|
|HMM build commands:||
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 80369284 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||6|
|Download:||download the raw HMM for this family|
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