# STOCKHOLM 1.0
#=GF ID   VEFS-Box
#=GF AC   PF09733.10
#=GF DE   VEFS-Box of polycomb protein
#=GF AU   KOGs;
#=GF AU   Finn RD;0000-0001-8626-2148
#=GF AU   Coggill P;0000-0001-5731-1588
#=GF SE   KOGs (KOG2350)
#=GF GA   21.10 21.10;
#=GF TC   21.10 21.40;
#=GF NC   21.00 21.00;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch --cut_ga HMM metaseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   11701882
#=GF RT   EMBRYONIC FLOWER2, a novel polycomb group protein homolog,
#=GF RT   mediates shoot development and flowering in Arabidopsis. 
#=GF RA   Yoshida N, Yanai Y, Chen L, Kato Y, Hiratsuka J, Miwa T, Sung
#=GF RA   ZR, Takahashi S; 
#=GF RL   Plant Cell. 2001;13:2471-2481.
#=GF RN   [2]
#=GF RM   11546753
#=GF RT   Su(z)12, a novel Drosophila Polycomb group gene that is
#=GF RT   conserved in vertebrates and plants. 
#=GF RA   Birve A, Sengupta AK, Beuchle D, Larsson J, Kennison JA,
#=GF RA   Rasmuson-Lestander A, Muller J; 
#=GF RL   Development. 2001;128:3371-3379.
#=GF DR   INTERPRO; IPR019135;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   The VEFS-Box (VRN2-EMF2-FIS2-Su(z)12) box is the C-terminal
#=GF CC   region of these proteins, characterised by an acidic cluster and
#=GF CC   a tryptophan/methionine-rich sequence, the acidic-W/M domain
#=GF CC   [1]. Some of these sequences are associated with a zinc-finger
#=GF CC   domain about 100 residues towards the N-terminus. This protein
#=GF CC   is one of the polycomb cluster of proteins which control HOX
#=GF CC   gene transcription as it functions in heterochromatin-mediated
#=GF CC   repression [2].
#=GF SQ   2
#=GS EBS35687.1/88-210  DE [subseq from] hypothetical protein GOS_7450210 [marine metagenome]
#=GS ECO22249.1/155-268 DE [subseq from] hypothetical protein GOS_6336926 [marine metagenome]
EBS35687.1/88-210          ------------------TFYHAKTCLPVWRNKNiiggsgDSGLDSDDDEDLHAWAKEDLRHLSDFEDVALLEKRFMHDWNVFVRRFRPCADKEIPDCLSAFARFKGKDLAGNrQLRRLFTLHLVNAYDFGVIEARVIDDV---
ECO22249.1/155-268         -------------TAETRQYYHITSRAVMNAN--......-PDSDSEDDEDIELTTHKIEAALDDFDDVNGSEKTLMKVWNRHLLKYPVLADSHSRALCEVFIDEHTAELQ--.ALRNNFMLHLSTMTRCGALQPEEMV-----
#=GC PP_cons               .............5789*9****99999986643......7679*******999999****************************************************98*9.9*******************9999886...
#=GC RF                    xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx......xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.xxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
//