Summary: Protein required for attachment to host cells
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Protein required for attachment to host cells Provide feedback
Members of this family of bacterial proteins are required for the attachment of the bacterium to host cells .
Matthysse AG, Yarnall H, Boles SB, McMahan S; , Biochim Biophys Acta. 2000;1490:208-212.: A region of the Agrobacterium tumefaciens chromosome containing genes required for virulence and attachment to host cells. PUBMED:10786639 EPMC:10786639
da Silva AC, Ferro JA, Reinach FC, Farah CS, Furlan LR, Quaggio RB, Monteiro-Vitorello CB, Van Sluys MA, Almeida NF, Alves LM, do Amaral AM, Bertolini MC, Camargo LE, Camarotte G, Cannavan F, Cardozo J, Chambergo F, Ciapina LP, Cicarelli RM, Coutinho LL, , Nature. 2002;417:459-463.: Comparison of the genomes of two Xanthomonas pathogens with differing host specificities. PUBMED:12024217 EPMC:12024217
- the number of sequences which exhibit this architecture
a textual description of the architecture, e.g. Gla, EGF x 2, Trypsin.
This example describes an architecture with one
Gladomain, followed by two consecutive
EGFdomains, and finally a single
- the UniProt description of the protein sequence
- the number of residues in the sequence
- the Pfam graphic itself.
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We make a range of alignments for each Pfam-A family:
- the curated alignment from which the HMM for the family is built
- the alignment generated by searching the sequence database using the HMM
- Representative Proteomes (RPs) at 15%, 35%, 55% and 75% co-membership thresholds
- alignment generated by searching the UniProtKB sequence database using the family HMM
- alignment generated by searching the NCBI sequence database using the family HMM
- alignment generated by searching the metagenomics sequence database using the family HMM
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Curation and family details
|Seed source:||COGs (COG5622)|
|Author:||COGs, Finn RD, Sammut SJ|
|Number in seed:||112|
|Number in full:||639|
|Average length of the domain:||131.50 aa|
|Average identity of full alignment:||26 %|
|Average coverage of the sequence by the domain:||88.50 %|
|HMM build commands:||
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 26740544 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||8|
|Download:||download the raw HMM for this family|
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