# STOCKHOLM 1.0
#=GF ID   TIR-like
#=GF AC   PF10137.10
#=GF DE   Predicted nucleotide-binding protein containing TIR-like domain
#=GF AU   COGs;
#=GF AU   Finn RD;0000-0001-8626-2148
#=GF AU   Sammut SJ;0000-0003-4472-904X
#=GF SE   COGs (COG4271)
#=GF GA   24.70 24.70;
#=GF TC   24.70 24.70;
#=GF NC   24.60 24.40;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch --cut_ga HMM metaseq
#=GF TP   Domain
#=GF DR   INTERPRO; IPR019302;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   Members of this family of bacterial nucleotide-binding proteins
#=GF CC   contain a TIR-like domain. Their exact function has not, as yet,
#=GF CC   been defined.
#=GF SQ   13
#=GS EDJ61997.1/147-266 DE [subseq from] hypothetical protein GOS_1663354 [marine metagenome]
#=GS EBT49095.1/29-147  DE [subseq from] hypothetical protein GOS_7265047 [marine metagenome]
#=GS 2004020891/75-197  DE [subseq from] 'Predicted nucleotide-binding protein containing T IR -like domain [Human Gut Community Subject 7]'
#=GS 2001404075/103-219 DE [subseq from] 'Predicted nucleotide-binding protein containing TIR -like domain [Whalefall Sample #1]'
#=GS ECP54398.1/125-222 DE [subseq from] hypothetical protein GOS_5663987 [marine metagenome]
#=GS 2001495560/113-226 DE [subseq from] 'Predicted nucleotide-binding protein containing TIR -like domain [Whalefall Sample #3]'
#=GS ECV08058.1/128-240 DE [subseq from] hypothetical protein GOS_2964870 [marine metagenome]
#=GS 2004025307/3-112   DE [subseq from] '[Human Gut Community Subject 8]'
#=GS 2000365560/6-120   DE [subseq from] '[Sludge/Australian, Phrap Assembly]'
#=GS EBS91440.1/7-54    DE [subseq from] hypothetical protein GOS_7359753 [marine metagenome]
#=GS ECN42415.1/131-189 DE [subseq from] hypothetical protein GOS_5990962 [marine metagenome]
#=GS 2001404831/1-36    DE [subseq from] '[Whalefall Sample #1]'
#=GS 2000465240/4-67    DE [subseq from] '[Sludge/Australian, Phrap Assembly]'
EDJ61997.1/147-266         KIFVVHG.SDDGSKETVARYLTK.LD..LHPIILNELPNQG-RTVIEKFEENTSDIDFAVILLTPDDIGYPAGCp.neAKPRARQNVVLELGYFIASL...GRHRVCALC...KGDVEIPSDISGVVYIPLD-
EBT49095.1/29-147          -VFIICSvEALPIARAIENNLEH.DK..FFVKTWTQGVFRASQYALESLEEQLDECDFAIAIAQPDDSVTMREE....TKNTPRDNVIFELGLFVGRL...GRARTFLLEp.rGDEVHLPSDLKGLTTIGY--
2004020891/75-197          KVFVVYG.HDRNARDQLELLLRK.LE..LIPLFLDDLPSGG-KTIIEKLEKYIPQANFGVVLLTPDDIGCKRTAp.qkARPRARQNVILELGMLYMKL...SRGRVALIVkksDDEIELPSDLEGIMRLNYM-
2001404075/103-219         KVFIVHG.HDEKARLPLSKILKDdLG..FEPVILQEEPNVSLETIITKFERLAKDCSAAIILFTPDDEANG---....-KLRARQNVILELGYFLGKFqcqPNRRIIIIK...TGEIEIPSDISGVLYLEY--
ECP54398.1/125-222         KVFIVHG.RDNETKQEVSRYIEQ.LG..LQAIILHEQASSG-MTIIEKIEHYSNEADFAIVLYTACDHGRGVHEskipPKNRARQNVVFEHGYLMAKL...GRENV----...--------------------
2001495560/113-226         RVFISHG.RSEEWR-KLQAYLEKdLE..HNTLELAQEANLG-RTILQKLSEEAQKCSVAVIVMTGDDITED---....GEIRARENVMHEIGFFQGFY...GLNNVVLLH...ESGVNIPSNIHGLVYIPFA-
ECV08058.1/128-240         -VFIGHG.RSSDWR-DLKDHLQDkHN..IKIEAYETGARAG-HTIRDILEDMANKSTFALLVMSAEDELPT---....GEFRARQNVIHEIGLFQGKL...GFNKAIVLM...EHGVEEFSNIYGVQQIRYS-
2004025307/3-112           -------.--VKIAEKVKSLLD-.GE..YVCQLWCDNFFDLGQCTYHELLKKSLSFDYAIFIGGKDDYVRRESDr..tHKYAARDNVYLEFGLYAGIL...TYARCFSLI...QEGCQIASDLLGVNVVFFD-
2000365560/6-120           -IFIGSStAAKSQAKAIVKAFTS.AT..VEFLPWWEAFTPG-RTLLEDLDAIRGQVDGALLLFSPEAEATVRGN....TVFTPNLNVLFEFGYFYGHF...GKQKVAMLK...YGDFYLPSDLGGYIHIN---
EBS91440.1/7-54            -------.---------------.--..--------------------------------------------DN....LRPRARQNVVFEHGYLIGKL...GRNRVIPLV...EQDLEIPNDISGVVYVG---
ECN42415.1/131-189         KIFVVHG.HDDGLKQGVLRFLEK.LG..LEGIVLHEQPSES-RTIIEKIEHYSATVGFGVILYT----------....--------------------...---------...--------------------
2001404831/1-36            -------.---------------.--..----------------------------------------------....------------LGYFIGKL...KRENVCALH...KGTVEIPSDYLGVLYIPFD-
2000465240/4-67            -IFISYShQDEKWKDALQKQLRV.LQlhADFTVWDDRQIDIGDTWLPQIEAAIAAAKVAILLISSD--------....--------------------...---------...--------------------
#=GC PP_cons               8******.**9***********9.99..********999999****************************9988....9*******************...********9...**************99887.
#=GC RF                    xxxxxxx.xxxxxxxxxxxxxxx.xx..xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx....xxxxxxxxxxxxxxxxxxxx...xxxxxxxxx...xxxxxxxxxxxxxxxxxxxx
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