Summary: Ribosomal subunit 39S
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Ribosomal subunit 39S Provide feedback
The 39S ribosomal protein appears to be a subunit of one of the larger mitochondrial 66S or 70S units . Under conditions of ethanol-stress in rats the larger subunit is largely dissociated into its smaller components . In E. coli, in the absence of the enzyme pseudouridine synthase (RluD) synthase, there is an accumulation of 50S and 30S subunits and the appearance of abnormal particles (62S and 39S), with concomitant loss of 70S ribosomes .
Cahill A, Baio DL, Ivester P, Cunningham CC; , Alcohol Clin Exp Res. 1996;20:1362-1367.: Differential effects of chronic ethanol consumption on hepatic mitochondrial and cytoplasmic ribosomes. PUBMED:8947311 EPMC:8947311
Gutgsell NS, Deutscher MP, Ofengand J; , RNA. 2005;11:1141-1152.: The pseudouridine synthase RluD is required for normal ribosome assembly and function in Escherichia coli. PUBMED:15928344 EPMC:15928344
External database links
This tab holds annotation information from the InterPro database.
InterPro entry IPR018305
This entry represents the L50 protein from the mitochondrial 39S ribosomal subunit. L50 appears to be a secondary RNA-binding protein [PUBMED:3129699]. The 39S ribosomal protein appears to be a subunit of one of the larger mitochondrial 66S or 70S units [PUBMED:8947311]. Under conditions of ethanol-stress in rats the larger subunit is largely dissociated into its smaller components [PUBMED:15928344].
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|Cellular component||mitochondrion (GO:0005739)|
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Curation and family details
|Author:||Buljan M, Coggill P|
|Number in seed:||30|
|Number in full:||196|
|Average length of the domain:||108.30 aa|
|Average identity of full alignment:||23 %|
|Average coverage of the sequence by the domain:||36.59 %|
|HMM build commands:||
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||4|
|Download:||download the raw HMM for this family|
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