Summary: Type II secretion system (T2SS), protein M subtype b
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Type II secretion system (T2SS), protein M subtype b Provide feedback
The T2SMb family is conserved in Proteobacteria and Actinobacteria, and differs from the T2SM proteins in Vibrio spp. (PF04612).
Peabody CR, Chung YJ, Yen MR, Vidal-Ingigliardi D, Pugsley AP, Saier MH Jr;, Microbiology. 2003;149:3051-3072.: Type II protein secretion and its relationship to bacterial type IV pili and archaeal flagella. PUBMED:14600218 EPMC:14600218
Desvaux M, Hebraud M, Talon R, Henderson IR;, Trends Microbiol. 2009;17:139-145.: Secretion and subcellular localizations of bacterial proteins: a semantic awareness issue. PUBMED:19299134 EPMC:19299134
Internal database links
|SCOOP:||DUF3333 AsmA_2 CNOT1_CAF1_bind|
External database links
This tab holds annotation information from the InterPro database.
InterPro entry IPR007690Type II secretion system protein M is a membrane protein involved in the export of proteins in bacteria. It consists of a short cytosolic N-terminal domain, a transmembrane domain, and a C-terminal periplasmic domain. The precise function of this protein is unknown, though in Vibrio cholerae, the EpsM protein interacts with the EpsL protein, and also forms homodimers [PUBMED:10322014],
|Biological process||extracellular transport (GO:0006858)|
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Curation and family details
|Previous IDs:||GspM_II; T2SM_b;|
|Author:||Mistry J, Coggill P, Desvaux M|
|Number in seed:||20|
|Number in full:||576|
|Average length of the domain:||107.00 aa|
|Average identity of full alignment:||26 %|
|Average coverage of the sequence by the domain:||54.77 %|
|HMM build commands:||
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 80369284 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||5|
|Download:||download the raw HMM for this family|
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