Summary: Phosphoribosyl transferase (PRTase)
Phosphoribosyl transferase (PRTase) Provide feedback
This PRTase family has a C terminal RNA binding Pelota domain . These genes are found in the biosynthetic operon associated with the Ter stress response operon and are predicted to be involved in the biosynthesis of a ribo- nucleoside involved in stress response .
Müller FH, Bandeiras TM, Urich T, Teixeira M, Gomes CM, Kletzin A , Mol Microbiol 2004;0:0-0.: Coupling of the Pathway of Sulfur Oxidation to Dioxygen Reduction: Characterization of a Novel Membrane-Bound Thiosulfate:Quinone Oxidoreductase 2 PUBMED:0 EPMC:0
External database links
- the number of sequences which exhibit this architecture
a textual description of the architecture, e.g. Gla, EGF x 2, Trypsin.
This example describes an architecture with one
Gladomain, followed by two consecutive
EGFdomains, and finally a single
- the UniProt description of the protein sequence
- the number of residues in the sequence
- the Pfam graphic itself.
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This superfamily of phosphoribosyl-transferases (PRTases) and phosphoribosyl-pyrophosphate synthetase-like protein families is characterised by a core fold of three layers, a/b/a with a mixed beta-sheet of six strands. In one of the families consists of two domains of this fold.
The clan contains the following 6 members:Pribosyl_synth Pribosyltran PRTase_1 PRTase_2 PRTase_3 UPRTase
We make a range of alignments for each Pfam-A family:
- the curated alignment from which the HMM for the family is built
- the alignment generated by searching the sequence database using the HMM
- Representative Proteomes (RPs) at 15%, 35%, 55% and 75% co-membership thresholds
- alignment generated by searching the NCBI sequence database using the family HMM
- alignment generated by searching the metagenomics sequence database using the family HMM
You can see the alignments as HTML or in three different sequence viewers:
- Pfam viewer
- an HTML-based viewer that uses DAS to retrieve alignment fragments on request
1Cannot generate PP/Heatmap alignments for seeds; no PP data available
Key: available, not generated, — not available.
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Curation and family details
|Seed source:||Anantharaman V|
|Author:||Anantharaman V, Pollington J, Finn RD|
|Number in seed:||68|
|Number in full:||350|
|Average length of the domain:||247.50 aa|
|Average identity of full alignment:||50 %|
|Average coverage of the sequence by the domain:||60.57 %|
|HMM build commands:||
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||3|
|Download:||download the raw HMM for this family|
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The tree shows the occurrence of this domain across different species. More...
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