Summary: Shoulder domain
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Shoulder domain Provide feedback
This domain is found in the Major Vault Protein and has been called the shoulder domain . This family includes two bacterial proteins A6FXE2 and A1ZGE7. This suggests that some bacteria may possess vault particles.
Tanaka H, Kato K, Yamashita E, Sumizawa T, Zhou Y, Yao M, Iwasaki K, Yoshimura M, Tsukihara T;, Science. 2009;323:384-388.: The structure of rat liver vault at 3.5 angstrom resolution. PUBMED:19150846 EPMC:19150846
External database links
This tab holds annotation information from the InterPro database.
InterPro entry IPR021870
This domain is found in the Major Vault Protein and has been called the shoulder domain [PUBMED:19150846]. This family includes two bacterial proteins SWISSPROT and SWISSPROT. This suggests that some bacteria may possess vault particles.
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Curation and family details
|Seed source:||Bateman A|
|Number in seed:||39|
|Number in full:||224|
|Average length of the domain:||117.60 aa|
|Average identity of full alignment:||57 %|
|Average coverage of the sequence by the domain:||14.80 %|
|HMM build commands:||
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 80369284 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||4|
|Download:||download the raw HMM for this family|
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The tree shows the occurrence of this domain across different species. More...
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For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe group, to allow us to map Pfam domains onto UniProt sequences and three-dimensional protein structures. The table below shows the structures on which the MVP_shoulder domain has been found. There are 3 instances of this domain found in the PDB. Note that there may be multiple copies of the domain in a single PDB structure, since many structures contain multiple copies of the same protein seqence.
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