# STOCKHOLM 1.0
#=GF ID RP1-2
#=GF AC PF12042.9
#=GF DE Tubuliform egg casing silk strands structural domain
#=GF AU Gavin OL;
#=GF GA 21.1 21.1
#=GF NC 19.9 20.9
#=GF TC 23.3 23.6
#=GF SE pdb_2k3n
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 47079205 -E 1000 --cpu 4 HMM pfamseq
#=GF TP Domain
#=GF RN [1]
#=GF RM 19458259
#=GF RT Solution structure of eggcase silk protein and its implications
#=GF RT for silk fiber formation.
#=GF RA Lin Z, Huang W, Zhang J, Fan JS, Yang D;
#=GF RL Proc Natl Acad Sci U S A. 2009;106:8906-8911.
#=GF DR INTERPRO; IPR021915;
#=GF DR SO; 0000417; polypeptide_domain;
#=GF CC Spiders use fibroins to make silk strands. This family includes
#=GF CC tubuliform silk fibroins which are used to protect egg cases.
#=GF CC This domain is a structural domain which is found in repeats of
#=GF CC up to 20 in many individuals (although this is not necessarily
#=GF CC the case). RP1 makes up structural domains in the N terminal
#=GF CC while RP2 makes up structural domains in the C terminal. [1]
#=GF SQ 37
A0A087URD1.1/240-401   ---AAVTPSGI.................ISEVTNNLASALLRSNVFQRVFNNRVPSSISTRIASELAQSIISKLQLDyTTASKCRNSIIQAVSGIRSGSDTRVYAQAIASVLTSELATTGRLN..ASNAS.VIGSSILSGILQGAYSAARQAGLdlsgidvTSDISSSLSAYSSSSAAPQTVAET------
A0A087URD1.1/441-593   ----------V.................ISNVANNLVTALLRSNVFQRAFNSRVPSSVVNRIAVALAQSIASSLQLDyGTASKCRNAITQALAGVRSGSDTRAYAVAIASAVSGQLAAVGRLN..SSNAS.SIGSSLLSSVVQGAYSAARQAGI.......DVSGVDVSSDISSSISAYGTGPAVAFDTA-
A0A087URD1.1/630-775   -----AVPSAV.................ISDVANNLASALLRSNIFQRSFNARISASVANRIAAALAQSIASSFQLDyATASKCRNAIMQALSSVRSGSDTRTYATAIATTLASQLAAAGRLN..TSNAS.GIGTTLLSGVLQGAYSGARQAGV.......DVSGVDVSTDISSSVSA-------------
A0A087URD1.1/821-979   --SSGAVPSSL.................ISDVANNIASALLRSNIFQRAFNARVSTSVANRIAVALTQSIASTFQLDyGTASKCRNAVMQALSSVRSGSDTRVYALAIASALAAQLAAAGRLN..ASNAS.SIGSSLLSGVVQGAYSGARQAGV.......DVSGVDVSSDISSSISAYGAGSAAGQD---
A0A087URD1.1/1021-1167 --------SGV.................ISDVANNLASALLRSNIFQRAFNARVSSSVANRISAALAQTIASSLQLDyATAVKCRNAIMQAISGVRSGSDTRAYALAIASALAAQLGNAGRLN..ASNAS.GIGSSLLSGVVQGAYSGARQAGV.......DMSGVDVSSDISSSISAYSAG---------
A0A087URD1.1/1209-1366 --SSGAVPSAL.................ISDLANNLASALLRSNVFQRAFNARNSSAVTNRIAAALAQSIVSSLQLDyGTASKFRNAITQALSSVRSGSNTRVYALAIASALAAQLAAAGRLN..ASNAS.SIGSSLLSGVVQGAYSGARQAGV.......DVSGVDVSSDISSSISAYGAGSAAGQ----
A0A087URD1.1/1401-1552 -APSAGAAPSV.................VSDVANTLASGLLTSNAFQRAFNSRISSSVANRIAAALAQSVASSMQLDyGTASKCRNAIMQALSSVRSGSDTRVYALTIASSLATQLANAGVLN..ASNMS.SIGSSLLSSVVQGAYSGARQAGI.......DVSGIDVSSDISSSISAYG-----------
A0A087URD1.1/1593-1755 GASSTGAAQSA................vVSDVANKIASALLRSNLFQRVFNTRISSSVASRIATTLAQTTASSLQLDyGTASKCRNAIMQALSGVRTGSDTRVYALAIASALAAQLAASGRLN..ASNAS.GIGSSVISGVVQGTYSGASQAGV.......DVSGVDVSSDISSSISAYGRGSAVGQDI--
A0A087URD1.1/1800-1951 -----------.................-SDVANNIASALLRSNIFQRAFNARVSTSVANRIAAALAQTIASSLQLDnATAAKCRNAIMQALSGVRSGSDTRIYALAIASALAGQLAAAGRLN..ASNAS.GIGSSLLSGVVQGAYSGARQTGI.......DVSGVDVSSDISSSISAFAAGSTAGQDVAS
A0A087URD1.1/1992-2142 ----------I.................ISDVANNLASALLRSNVFKRAFNVRVSSNVANRIAGALAQSIASSLQLDfGTASKCRNAITQALSGVRSGSDTRVYALAISSALTAQLAAAGRLN..ASNAS.GIGSSLLSGVVQGTYSGAKQAGV.......DVSGVDVSSDISSSVSAYGAGPTGAQE---
A0A087URD1.1/2184-2335 --------SSI.................ISDVANNLASALLRSNIFQRAFNARISSSVANRIAAALAQSISSSMQLDyATASKCRNAIMQALSGVRSGSDTRVYALAIASALVAQLAAAGRLN..ASNAS.GIGSSVLPGVVQGAYSGARQAGV.......DVTGVDLSSDISSSISAFGGSSIGGQ----
A0A087URD1.1/2375-2527 --------SGV.................ISDVANNLASALLRSNVFQRAFNVRVSSSVANRIAGVLAQSIASSLQLDyGTASKCRNAIMQALSGVRSGSDTRVYALAIASALTTQLAAAGRLN..ESNAS.GIGSSLLSGVVQGTYSGAKQAGV.......DVSGVDVSSDISSSVSAYGAGPTGAQE---
A0A087URD1.1/2573-2724 -----------.................-SDVGNNLASALLRSNVFQRAFNARISSSVVSRIATALTQSISSSMQLDyATASKCRNAIMQALSGVRSGSDTRTYALAIASALVAQLAAAGRLN..ASNAS.GIGSSLLSGVVQGAYSGARQAGV.......DVTGVDVSSDISSSISAFGGSSTGGQGIAA
A0A087URD1.1/2766-2918 -----------.................ISDVANNLASALLRSNVFQRAFNARISSSIANKVAAALTQTLASSLQLDySTAAKCRNAIMQALSAVRSGSDTRVYALAIASSLVAQLAAAGRLD..ASNAS.GIGSSLLSGVVQGAYSGARQAGV.......DVSGIDVSTDISSSISTYGAGSPAGQDIAA
A0A087URD1.1/2958-3112 ---------DV.................ISDVANNLASALLRSNVFQRSFNPRVSSSVTNRIAAALAQSICTSLQLDyRTASKCRSAIMQALSSVRTGSDTRVYALAIASALAAQLAASGRLN..ASNAS.SIGSSLLSGVVQGAYSGARQAGV.......DVSGVDVSTDISSSISAYGAGSTAAQDISA
A0A087URD1.1/3153-3303 ----------L.................ISDIASNLASALVRSKIFQRAFNARVSSSIANRIASALTQSIASSLQLDnTTASKCRIAVTQALSSVRSGSDTRAYALSIASALARQLAAVGRLN..SSNAS.SIGSSLLSGVVQGAYSGARQAGV.......DVSGVDVSSDISSSVSAYGAGRTVSSE---
A0A087URD1.1/3348-3497 -----------.................ISEVASKLASALLRSNIFQLAFNARVSSSVASRIAAVLVQSIASSLQLDyGTASKCRNAIMQALSGVRTGSETRAYALTVASALATQLAGAGRLN..ASNAS.DIGSSVLSAAVQGAYSGASQAGV.......DVSGVDVSSDISSSISAYGAGPTGGSE---
A0A087URD1.1/3535-3693 ----AAVPSRV.................ISEVANKLASALLRSSVFQRAFNTRVSSSVANRIASALAQSIASSLQLDyATASKCRNAIMQALSGVRSGSDTSVYALAIASALAGQLAATGRLS..ASNAS.GIGSSLLSGVVQGSYSGARQAGV.......DLSGVDVSSDISSSLSAYGADSSAGQDIA-
A0A087URD1.1/3734-3878 ---------GV.................ISDVANNLASALLRSNIFQRAFNGRVSSSVANRIGAALAQSIASTLQLDyGTAAKCRNAIMQALSGVRSGSDTRVYALAIASAVVAQLAAAGRLN..TSNAS.GIGSSLLSGVVQGTYSGAKQAGV.......DVSGVDVSSDISSSISAYGA----------
A0A087URD1.1/3918-4077 ---AAAVPSGV.................ISDVVNNLASALLRSNSFQRAFNARVSSSVANRIVVALSQSIASNLQLDyGTASKLRNAVVQALSGVRSGSDTRVYAVTIASSLAAQLANAGLLK..ASNAS.SIGSSLLSSIVQGSYSGARQAGV.......DVSGIDIRSDISTSASAYSSSASSIQTSS-
A0A087TBY8.1/339-469   ---SSSSDIDV.................ISKFTNSITSSLLSSNDFTSTFRTGLPATTAVNLASSLARSFATQMALDeTTINTLLPLVSQYVSEISSSADVSAYANAISRAVGDALASTGNVP..PVLTA.SLAPADTQPIANLVNSVTSTNVN.......------------------------------
A0A087TBY8.1/543-670   ----------Rni.............dvISQFTNTITSSLLSSNEFTSIFGSGLPVTTALNLASNLAQSLAAQIGLDeTGINYLLSLLRQYISAIDLSADASAYANAVSRAIGNALASAGNLS..PALAS.SLASADTQPIANLVNSVTSSTLI.......------------------------------
A0A087TBY8.1/710-850   ----------AgggqgagtsstttdievISKFTNTVISSLLSSNDFTSIFGSGLPVTTALNLASNLAQSLATQIGLDeAGINSVLSLLNQYISAIDPSADASTYANALSLAIGNTLASAGSLS..PALAS.SLASVDAQPIANFVSSVASKTLN.......------------------------------
A0A087TBY8.1/901-1049  QSASAAASAAAgggqgvgtsstttdidvISKFTNAITSTLLSSNDFTSLFKSGLPVTAAVNLASNLALSLANQIGLDqAGINSLLSLLSQYISTIDSSADASAYANALSLAIVNTLANAESLS..PTLAS.YLASADTQPFANFVSSVTSRT--.......------------------------------
A0A087TBY8.1/1112-1252 ------AGGAQvagtsn....satdidvISKFINTISSSLLSSNDFTSIFGSGLPVTSALNLASNLAHSLATQIGLDeAGINSLLSLLSQYISAIDSSADASAYANALSLAIGSTLASAGSLS..PALAS.SLASADTQRIANFVSSVTSRTLN.......------------------------------
A0A087TBY8.1/1303-1450 QSASAATSTAAggaqgagtygtatdidvISKFTNTISSSLLSSNDFTSIFGSELPVATAFNLASNLAQSLATQIGLDeAGINSLLSLLSQYISAIGSSGDASAYANALSLAIGNTLASAGSLS..PALAS.SLASANAQAIANFVRSVTSR---.......------------------------------
A0A087TBY8.1/1518-1653 ----------Qvagtss....tatdigvISKFTNTVSSSLLSSNDFTSIFGSGLPVTTAFNLASNLAQSLATQIGLDeAGINSLLSLLSQYISAIGSSADASAYANALSLAIGNTLAKAGNLS..PILTA.SLASADAQPIANLVNSVTSSTL-.......------------------------------
A0A087U004.1/199-346   --TTSQQVTSA.................SSSFIEQLYNALINDSGFQSAFSGTVSTNIINAFATAIAGSVASASEFSsVGYSSLVKAYLQALSSEKDGATIEDYARAIATATSNVLEQNGIFS..EGVAS.GHITAAVNAITSGISSTHITESA.......VTTTSV--GSQTTVSSDA------------
A0A087U004.1/689-830   -----------.................ARNFGRLIYNSLLADEKFSSVFGIGNSFVNIRLFLTTLATSICSFPQFSsVTVSELVGKYIQAITPIPQGSDIHQYAQAIAQATAEIMSSRKLLS..LQGVT.ALSSSLESAISSALESSSKST--.......SVTQKSSSEIITTATAESGET---------
A0A087U004.1/843-979   ---------GI.................ASKFASSLYNSLLSNELFQAIFSHIQNTEHLDSYGKALIKNVF-SLGN-.INVSELSDNLLKAFQTIPLGSSLSQYAQVIVNTVAEAFIKHEVLI..PGNEE.SLAASTLNVLISGLREQSEEEAA.......QVSISKA-TAAIPVVA--------------
A0A087U004.1/1776-1919 ----AAGTSVF.................AADFGRQIYEALLSNPKFAEAFTGAITILRIRPFFTVLAENIIAIPVFSsLTLNELVDPYISAVLRIERGSSLRAYAQEIAGLTVEILLSRNLLT..AEAAS.LARTSVQSAISTALESTSTTTET.......-STTSAVATAESEGV---------------
A0A087U004.1/3236-3379 ---AAAGTSSY.................AAEFGRQIYDALLSNPRFTETFAGEITLLRIRPFFTVLAENIIAIPVFSsLTLNDLVDPYISAVLRIERGSSLRAYAQEIAGLTVEILLSRNLLT..AEAAS.LARTSVQRAISTALESTSTRTET......sTTTAVETAESES------------------
A0A087U004.1/3900-4043 ---AAAGTTSY.................AAEFGRQIYDALLSNPRFTETFAGEITLLRIRPFFTVLAENIIAIPVFSsLTLNDLVDPYISAVLRIERGSSLRAYAQEIAGLTVEILLSRNLLT..AEAAS.LARTSVQRAISTALESTSTRTET......sTTTAVETAESES------------------
A0A087UJV0.1/65-180    --------QDT.................TAAFSDSLYFQLMNSMAFRNIFDGRATPDFIINVGRNIAQGIALELRL-.QDVSSVINFIVNTLSSVYPGAGPEEYASAIADSILQIMLTNNILT..GNNPL.TFAGRLASIIDNALS--------.......------------------------------
A0A087UQ25.1/562-663   -----------.................-------LENALVSSEPFLEIFNPSTTSEDAAIYATLIAREALSEYGA-.PVVEDVDTVVRDAMSNLPPGSSSSDYASSLVNSIIATLNMYGLTT..DIQPE.FLASTMLLNLD------------.......------------------------------
A0A087TBZ4.1/240-354   -----------.................AKKFSETLFVALLKSNLFRETFVRTISKVRAQYLAFKMAFHAITNYGYS.EYAKETAYACAASIKLLPKNSAPQAFGGKISKAITSIFYQKGLIQenTREQAqYLASEMLNYLSNI----------.......------------------------------
A0A087UPZ6.1/49-143    -----------.................-ESFRESLYSQIINSASFSIKFGGSVTDVDIINVGRNIATGIASELNL-.QDYDSVSNFMISALGSVYPVGKLEDYASIIVEAVLELLSTYNILN..EYN--.-----------------------.......------------------------------
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