Summary: heparan sulfate-N-deacetylase
heparan sulfate-N-deacetylase Provide feedback
This family of proteins is are heparan sulfate N-deacetylase enzymes. This protein is found in eukaryotes. This proteinenzyme is often found associated with PF00685.
Dixon J, Loftus SK, Gladwin AJ, Scambler PJ, Wasmuth JJ, Dixon MJ;, Genomics. 1995;26:239-244.: Cloning of the human heparan sulfate-N-deacetylase/N-sulfotransferase gene from the Treacher Collins syndrome candidate region at 5q32-q33.1. PUBMED:7601448 EPMC:7601448
External database links
This tab holds annotation information from the InterPro database.
InterPro entry IPR021930
This family of proteins is are heparan sulphate N-deacetylase enzymes. This protein is found in eukaryotes. This enzyme is often found associated with .
The mapping between Pfam and Gene Ontology is provided by InterPro. If you use this data please cite InterPro.
|Molecular function||hydrolase activity (GO:0016787)|
|[heparan sulfate]-glucosamine N-sulfotransferase activity (GO:0015016)|
- the number of sequences which exhibit this architecture
a textual description of the architecture, e.g. Gla, EGF x 2, Trypsin.
This example describes an architecture with one
Gladomain, followed by two consecutive
EGFdomains, and finally a single
- the UniProt description of the protein sequence
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We make a range of alignments for each Pfam-A family:
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Curation and family details
|Seed source:||PFAM-B_2134 (release 23.0)|
|Author:||Assefa S, Coggill P, Bateman A|
|Number in seed:||26|
|Number in full:||446|
|Average length of the domain:||385.90 aa|
|Average identity of full alignment:||58 %|
|Average coverage of the sequence by the domain:||55.18 %|
|HMM build commands:||
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 80369284 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||4|
|Download:||download the raw HMM for this family|
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