# STOCKHOLM 1.0
#=GF ID   STAT1_TAZ2bind
#=GF AC   PF12162.9
#=GF DE   STAT1 TAZ2 binding domain
#=GF AU   Mistry J;0000-0003-2479-5322
#=GF AU   Gavin OL;
#=GF SE   pdb_2ka6
#=GF GA   21.60 21.60;
#=GF TC   21.60 26.30;
#=GF NC   21.50 21.10;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 47079205 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Motif
#=GF RN   [1]
#=GF RM   19214187
#=GF RT   Structural basis for recruitment of CBP/p300 coactivators by
#=GF RT   STAT1 and STAT2 transactivation domains.
#=GF RA   Wojciak JM, Martinez-Yamout MA, Dyson HJ, Wright PE;
#=GF RL   EMBO J. 2009;28:948-958.
#=GF DR   INTERPRO; IPR022752;
#=GF DR   SO; 0001067; polypeptide_motif;
#=GF CC   This domain family is found in eukaryotes, and is approximately
#=GF CC   20 amino acids in length, and the family is found in association
#=GF CC   with Pfam:PF02865, Pfam:PF00017, Pfam:PF01017, Pfam:PF02864.
#=GF CC   This domain is the C terminal domain of STAT1. This domain binds
#=GF CC   selectively to the TAZ2 domain of CRB (CREB-binding protein). In
#=GF CC   this process it becomes a transcriptional activator and can
#=GF CC   initiate transcription of certain genes.
#=GF SQ   7
#=GS F6UJK9_XENTR/719-743  AC F6UJK9.1
#=GS H7BZ88_HUMAN/5-29     AC H7BZ88.1
#=GS G1N4C3_MELGA/717-741  AC G1N4C3.2
#=GS W5MV00_LEPOC/713-735  AC W5MV00.1
#=GS Q6P943_DANRE/712-734  AC Q6P943.1
#=GS I3K2L6_ORENI/713-735  AC I3K2L6.1
#=GS H3C088_TETNG/712-734  AC H3C088.1
F6UJK9_XENTR/719-743             SRLQTTEFLLPMSPDEYAEVARLVG
H7BZ88_HUMAN/5-29                SRLQTTDNLLPMSPEEFDEVSRIVG
G1N4C3_MELGA/717-741             SRLQSPENLLPMSPEEFDEVSRMVD
W5MV00_LEPOC/713-735             SRLQSTETMLPLSPEDFGELTRI..
Q6P943_DANRE/712-734             QEYN..ENLMPMSPEVYGELERMNR
I3K2L6_ORENI/713-735             SRLQ..DNMMPMSPDDYKALEQYVS
H3C088_TETNG/712-734             SKLQ..DNMMPMSPDDYNALRQLVT
#=GC seq_cons                    SRLQ..-NhhPMSP--asElpRhVs
//