Summary: Type 5 capsule protein repressor C-terminal domain
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Type 5 capsule protein repressor C-terminal domain Provide feedback
This domain is found in bacteria and archaea. This domain is about 90 amino acids in length. This domain is found associated with PF00149. SbcD works in complex with SbdC (SbcDC) which is a transcription regulator. It down-regulates transcription of arl and mgr to inhibit type 5 capsule protein production. It acts as part of the SOS pathway of bacteria.
Chen Z, Luong TT, Lee CY;, J Bacteriol. 2007;189:7343-7350.: The sbcDC locus mediates repression of type 5 capsule production as part of the SOS response in Staphylococcus aureus. PUBMED:17704228 EPMC:17704228
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Curation and family details
|Seed source:||PFAM-B_3790 (release 23.0)|
|Author:||Assefa S, Gavin OL, Bateman A|
|Number in seed:||203|
|Number in full:||1897|
|Average length of the domain:||98.00 aa|
|Average identity of full alignment:||23 %|
|Average coverage of the sequence by the domain:||25.01 %|
|HMM build commands:||
build method: hmmbuild --amino -o /dev/null HMM SEED
search method: hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||3|
|Download:||download the raw HMM for this family|
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For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe group, to allow us to map Pfam domains onto UniProt sequences and three-dimensional protein structures. The table below shows the structures on which the SbcD_C domain has been found. There are 8 instances of this domain found in the PDB. Note that there may be multiple copies of the domain in a single PDB structure, since many structures contain multiple copies of the same protein seqence.
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