Summary: Tungro spherical virus-type peptidase
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Tungro spherical virus-type peptidase Provide feedback
This is the protease for self-cleavage of the positive single-stranded polyproteins of a number of plant viral genomes. The protease activity of the polyprotein is at the C-terminal end, adjacent to the putative RNA polymerase.
Thole V, Hull R;, Virology. 1998;247:106-114.: Rice tungro spherical virus polyprotein processing: identification of a virus-encoded protease and mutational analysis of putative cleavage sites. PUBMED:9683576 EPMC:9683576
Internal database links
|Similarity to PfamA using HHSearch:||Peptidase_C4 Peptidase_C3|
External database links
This tab holds annotation information from the InterPro database.
InterPro entry IPR024387
This entry represents a rice tungro spherical waikavirus-type peptidase that belongs to MEROPS peptidase family C3G. It is a picornain 3C-type protease, and is responsible for the self-cleavage of the positive single-stranded polyproteins of a number of plant viral genomes. The location of the protease activity of the polyprotein is at the C-terminal end, adjacent and N-terminal to the putative RNA polymerase [PUBMED:9683576, PUBMED:15503215].
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This clan contains a diverse set of peptidases with the trypsin fold.
The clan contains the following 24 members:DUF1986 DUF31 DUF316 Peptidase_C24 Peptidase_C3 Peptidase_C30 Peptidase_C37 Peptidase_C3G Peptidase_C4 Peptidase_C62 Peptidase_S29 Peptidase_S3 Peptidase_S30 Peptidase_S31 Peptidase_S32 Peptidase_S39 Peptidase_S46 Peptidase_S55 Peptidase_S6 Peptidase_S7 Peptidase_S76 Pico_P2A Trypsin Trypsin_2
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Curation and family details
|Number in seed:||3|
|Number in full:||29|
|Average length of the domain:||225.10 aa|
|Average identity of full alignment:||36 %|
|Average coverage of the sequence by the domain:||9.79 %|
|HMM build commands:||
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||3|
|Download:||download the raw HMM for this family|
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