# STOCKHOLM 1.0
#=GF ID   PTP_N
#=GF AC   PF12453.9
#=GF DE   Protein tyrosine phosphatase N terminal 
#=GF AU   Gavin OL;
#=GF SE   Prosite
#=GF GA   21.90 21.90;
#=GF TC   21.90 22.20;
#=GF NC   21.80 19.80;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 47079205 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   19327423
#=GF RT   Effect of cholesterol crystals on plaques and intima in arteries
#=GF RT   of patients with acute coronary and cerebrovascular syndromes.
#=GF RA   Abela GS, Aziz K, Vedre A, Pathak DR, Talbott JD, Dejong J;
#=GF RL   Am J Cardiol. 2009;103:959-968.
#=GF DR   INTERPRO; IPR024739;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This domain family is found in eukaryotes, and is approximately
#=GF CC   30 amino acids in length. The family is found in association
#=GF CC   with Pfam:PF00041. There is a single completely conserved
#=GF CC   residue L that may be functionally important. This family
#=GF CC   consists of various protein tyrosine phosphatase haematopoietic
#=GF CC   receptors, e.g. CD45, which dephosphorylate growth stimulating
#=GF CC   proteins. This limits growth signalling in haematopoietic cells.
#=GF SQ   4
#=GS W5Q2D7_SHEEP/7-32  AC W5Q2D7.1
#=GS Q0VAE8_HUMAN/5-30  AC Q0VAE8.1
#=GS L9K5S5_TUPCH/7-32  AC L9K5S5.1
#=GS M3YGB4_MUSPF/7-32  AC M3YGB4.1
W5Q2D7_SHEEP/7-32             LKLLAFGFAFLDTAVSVAGNFTGPST
Q0VAE8_HUMAN/5-30             LKLLAFGFAFLDTEVFVTGQSPTPSP
L9K5S5_TUPCH/7-32             LKLLAFGFVFLDPEVFVTVESNTSSP
M3YGB4_MUSPF/7-32             LKLWAFAFAFLDAGVFVTGEDLSSST
#=GC seq_cons                 LKLLAFGFAFLDstVFVTGpssosSs
//