Summary: Rhomboid serine protease
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Rhomboid serine protease Provide feedback
This domain family is found in eukaryotes, and is approximately 210 amino acids in length. The family is found in association with PF01694. Rhomboid is a seven-transmembrane spanning protein that resides in the Golgi and acts as a serine protease to cleave Spitz.
Nakagawa T, Guichard A, Castro CP, Xiao Y, Rizen M, Zhang HZ, Hu D, Bang A, Helms J, Bier E, Derynck R;, Dev Dyn. 2005;233:1315-1331.: Characterization of a human rhomboid homolog, p100hRho/RHBDF1, which interacts with TGF-alpha family ligands. PUBMED:15965977 EPMC:15965977
External database links
This tab holds annotation information from the InterPro database.
InterPro entry IPR022241
This domain family is found in eukaryotes, and is approximately 210 amino acids in length. The family is found in association with . Rhomboid is a seven-transmembrane spanning protein that resides in the Golgi and acts as a serine protease to cleave Spitz.
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Curation and family details
|Number in seed:||31|
|Number in full:||130|
|Average length of the domain:||199.70 aa|
|Average identity of full alignment:||59 %|
|Average coverage of the sequence by the domain:||25.43 %|
|HMM build commands:||
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||3|
|Download:||download the raw HMM for this family|
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