Summary: Adenylate cyclase NT domain
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Adenylate cyclase NT domain Provide feedback
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This tab holds annotation information from the InterPro database.
InterPro entry IPR024685Adenylate cyclase is the enzyme responsible for the synthesis of cAMP from ATP. On the basis of sequence similarity, it has been proposed that there are three different classes of adenylate cyclases [PUBMED:7863008, PUBMED:8418825]. Class I cyclases are found in enterobacteria and related Gram-negative bacteria. This entry represents the N-terminal domain of class-I adenylate cyclases.
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This clan contains a diverse set of nucleotidyltransferase enzymes.
The clan contains the following 23 members:AbiEii Adenyl_cycl_N Adenyl_transf Aminoglyc_resit DNA_pol_B_palm DUF2204 DUF294 DZF GlnE GrpB LicD MdcG Mmp37 NTP_transf_2 NTP_transf_5 NTP_transf_6 NTP_transf_7 NTP_transf_8 Nuc-transf PolyA_pol Pox_polyA_pol RelA_SpoT RsfS
We make a range of alignments for each Pfam-A family:
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Curation and family details
|Seed source:||Ref |
|Author:||Finn RD, Bateman A|
|Number in seed:||61|
|Number in full:||4305|
|Average length of the domain:||193.00 aa|
|Average identity of full alignment:||76 %|
|Average coverage of the sequence by the domain:||23.22 %|
|HMM build commands:||
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 80369284 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||3|
|Download:||download the raw HMM for this family|
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