Summary: Alkaline and neutral invertase
This is the Wikipedia entry entitled "Glycoside hydrolase family 100". More...
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Glycoside hydrolase family 100 Edit Wikipedia article
|Alkaline and neutral invertase|
Glycoside hydrolases EC 3.2.1. are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycoside hydrolases, based on sequence similarity, has led to the definition of >100 different families. This classification is available on the CAZy(http://www.cazy.org/GH1.html) web site, and also discussed at CAZypedia, an online encyclopedia of carbohydrate active enzymes.
- Henrissat B, Callebaut I, Mornon JP, Fabrega S, Lehn P, Davies G (1995). "Conserved catalytic machinery and the prediction of a common fold for several families of glycosyl hydrolases". Proc. Natl. Acad. Sci. U.S.A. 92 (15): 7090–7094. doi:10.1073/pnas.92.15.7090. PMC 41477. PMID 7624375.
- Henrissat B, Davies G (1995). "Structures and mechanisms of glycosyl hydrolases". Structure 3 (9): 853–859. doi:10.1016/S0969-2126(01)00220-9. PMID 8535779.
- Bairoch, A. "Classification of glycosyl hydrolase families and index of glycosyl hydrolase entries in SWISS-PROT". 1999.
- Henrissat, B. and Coutinho P.M. "Carbohydrate-Active Enzymes server". 1999.
- CAZypedia, an online encyclopedia of carbohydrate-active enzymes.
- Lee HS, Sturm A (1996). "Purification and characterization of neutral and alkaline invertase from carrot.". Plant Physiol 112 (4): 1513–22. doi:10.1104/pp.112.4.1513. PMC 158084. PMID 8972597.
- Sturm A (1999). "Invertases. Primary structures, functions, and roles in plant development and sucrose partitioning.". Plant Physiol 121 (1): 1–8. doi:10.1104/pp.121.1.1. PMC 1539224. PMID 10482654.
Alkaline and neutral invertase Provide feedback
This is a family of bacterial and plant alkaline and neutral invertases, EC:22.214.171.124, previously known as Invertase_neut PF04853.
Internal database links
|Similarity to PfamA using HHSearch:||GDE_C|
External database links
This tab holds annotation information from the InterPro database.
InterPro entry IPR024746
O-Glycosyl hydrolases (EC) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families [PUBMED:7624375, PUBMED:8535779]. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site.Glycosyl hydrolase family 100 includes enzymes with invertase activity [PUBMED:8972597, PUBMED:10482654].
The mapping between Pfam and Gene Ontology is provided by InterPro. If you use this data please cite InterPro.
|Molecular function||glycopeptide alpha-N-acetylgalactosaminidase activity (GO:0033926)|
- the number of sequences which exhibit this architecture
a textual description of the architecture, e.g. Gla, EGF x 2, Trypsin.
This example describes an architecture with one
Gladomain, followed by two consecutive
EGFdomains, and finally a single
- the UniProt description of the protein sequence
- the number of residues in the sequence
- the Pfam graphic itself.
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This Clan includes CAZy clans GH-L, GH-M and GH-G. The members of this clan share a common structure composed of 6 helical hairpins. Most members of this superfamily are glycosyl hydrolase enzymes.
The clan contains the following 26 members:A2M_comp Bac_rhamnosid C5-epim_C Cobalamin_bind DUF1237 DUF608 GDE_C GlcNAc_2-epim Glyco_hydro_100 Glyco_hydro_127 Glyco_hydro_15 Glyco_hydro_47 Glyco_hydro_48 Glyco_hydro_63 Glyco_hydro_65m Glyco_hydro_76 Glyco_hydro_8 Glyco_hydro_88 Glyco_hydro_9 Glycoamylase LANC_like Pec_lyase Prenyltrans SQHop_cyclase_C SQHop_cyclase_N Trehalase
We make a range of alignments for each Pfam-A family:
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- Representative Proteomes (RPs) at 15%, 35%, 55% and 75% co-membership thresholds
- alignment generated by searching the NCBI sequence database using the family HMM
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1Cannot generate PP/Heatmap alignments for seeds; no PP data available
Key: available, not generated, — not available.
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Curation and family details
|Number in seed:||44|
|Number in full:||654|
|Average length of the domain:||353.80 aa|
|Average identity of full alignment:||53 %|
|Average coverage of the sequence by the domain:||74.70 %|
|HMM build commands:||
build method: hmmbuild --amino -o /dev/null HMM SEED
search method: hmmsearch -Z 80369284 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||3|
|Download:||download the raw HMM for this family|
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