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40  structures 4140  species 0  interactions 21769  sequences 3376  architectures

Family: Laminin_G_3 (PF13385)

Summary: Concanavalin A-like lectin/glucanases superfamily

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The Pfam group coordinates the annotation of Pfam families in Wikipedia, but we have not yet assigned a Wikipedia article to this family. If you think that a particular Wikipedia article provides good annotation, please let us know.

This tab holds the annotation information that is stored in the Pfam database. As we move to using Wikipedia as our main source of annotation, the contents of this tab will be gradually replaced by the Wikipedia tab.

Concanavalin A-like lectin/glucanases superfamily Provide feedback

This domain belongs to the Concanavalin A-like lectin/glucanases superfamily.

Internal database links

This tab holds annotation information from the InterPro database.

No InterPro data for this Pfam family.

Domain organisation

Below is a listing of the unique domain organisations or architectures in which this domain is found. More...

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Alignments

We store a range of different sequence alignments for families. As well as the seed alignment from which the family is built, we provide the full alignment, generated by searching the sequence database (reference proteomes) using the family HMM. We also generate alignments using four representative proteomes (RP) sets and the UniProtKB sequence database. More...

View options

We make a range of alignments for each Pfam-A family. You can see a description of each above. You can view these alignments in various ways but please note that some types of alignment are never generated while others may not be available for all families, most commonly because the alignments are too large to handle.

  Seed
(115)
Full
(21769)
Representative proteomes UniProt
(84052)
RP15
(4654)
RP35
(11463)
RP55
(21258)
RP75
(31782)
Jalview View  View  View  View  View  View  View 
HTML View             
PP/heatmap 1            

1Cannot generate PP/Heatmap alignments for seeds; no PP data available

Key: ✓ available, x not generated, not available.

Format an alignment

  Seed
(115)
Full
(21769)
Representative proteomes UniProt
(84052)
RP15
(4654)
RP35
(11463)
RP55
(21258)
RP75
(31782)
Alignment:
Format:
Order:
Sequence:
Gaps:
Download/view:

Download options

We make all of our alignments available in Stockholm format. You can download them here as raw, plain text files or as gzip-compressed files.

  Seed
(115)
Full
(21769)
Representative proteomes UniProt
(84052)
RP15
(4654)
RP35
(11463)
RP55
(21258)
RP75
(31782)
Raw Stockholm Download   Download   Download   Download   Download   Download   Download  
Gzipped Download   Download   Download   Download   Download   Download   Download  

You can also download a FASTA format file containing the full-length sequences for all sequences in the full alignment.

HMM logo

HMM logos is one way of visualising profile HMMs. Logos provide a quick overview of the properties of an HMM in a graphical form. You can see a more detailed description of HMM logos and find out how you can interpret them here. More...

Trees

This page displays the phylogenetic tree for this family's seed alignment. We use FastTree to calculate neighbour join trees with a local bootstrap based on 100 resamples (shown next to the tree nodes). FastTree calculates approximately-maximum-likelihood phylogenetic trees from our seed alignment.

Note: You can also download the data file for the tree.

Curation and family details

This section shows the detailed information about the Pfam family. You can see the definitions of many of the terms in this section in the glossary and a fuller explanation of the scoring system that we use in the scores section of the help pages.

Curation View help on the curation process

Seed source: Jackhmmer:C0A826
Previous IDs: none
Type: Domain
Sequence Ontology: SO:0000417
Author: Bateman A
Number in seed: 115
Number in full: 21769
Average length of the domain: 158.80 aa
Average identity of full alignment: 15 %
Average coverage of the sequence by the domain: 13.66 %

HMM information View help on HMM parameters

HMM build commands:
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 57096847 -E 1000 --cpu 4 HMM pfamseq
Model details:
Parameter Sequence Domain
Gathering cut-off 27.6 27.6
Trusted cut-off 27.6 27.6
Noise cut-off 27.5 27.5
Model length: 152
Family (HMM) version: 8
Download: download the raw HMM for this family

Species distribution

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Viruses Viruses Unclassified Unclassified
Viroids Viroids Unclassified sequence Unclassified sequence

Selections

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This visualisation provides a simple graphical representation of the distribution of this family across species. You can find the original interactive tree in the adjacent tab. More...

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Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe group, to allow us to map Pfam domains onto UniProt sequences and three-dimensional protein structures. The table below shows the structures on which the Laminin_G_3 domain has been found. There are 40 instances of this domain found in the PDB. Note that there may be multiple copies of the domain in a single PDB structure, since many structures contain multiple copies of the same protein sequence.

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AlphaFold Structure Predictions

The list of proteins below match this family and have AlphaFold predicted structures. Click on the protein accession to view the predicted structure.

Protein Predicted structure External Information
A0A0G2JV12 View 3D Structure Click here
A0A1D6QSM7 View 3D Structure Click here
A1A5Y0 View 3D Structure Click here
A4IB63 View 3D Structure Click here
B5X561 View 3D Structure Click here
D3ZF17 View 3D Structure Click here
F1LPD0 View 3D Structure Click here
F1LR02 View 3D Structure Click here
F4I9T0 View 3D Structure Click here
O35206 View 3D Structure Click here
O94985 View 3D Structure Click here
P20909 View 3D Structure Click here
P39059 View 3D Structure Click here
P39061 View 3D Structure Click here
Q19317 View 3D Structure Click here
Q4CKT4 View 3D Structure Click here
Q4CKZ4 View 3D Structure Click here
Q4CLL1 View 3D Structure Click here
Q4CMU9 View 3D Structure Click here
Q4CN26 View 3D Structure Click here
Q4CN53 View 3D Structure Click here
Q4CPD1 View 3D Structure Click here
Q4CPF9 View 3D Structure Click here
Q4CPU0 View 3D Structure Click here
Q4CQK4 View 3D Structure Click here
Q4CQL8 View 3D Structure Click here
Q4CQU8 View 3D Structure Click here
Q4CQZ7 View 3D Structure Click here
Q4CR60 View 3D Structure Click here
Q4CRP8 View 3D Structure Click here
Q4CRR6 View 3D Structure Click here
Q4CRS4 View 3D Structure Click here
Q4CRY2 View 3D Structure Click here
Q4CS58 View 3D Structure Click here
Q4CSS7 View 3D Structure Click here
Q4CST1 View 3D Structure Click here
Q4CSW3 View 3D Structure Click here
Q4CSZ4 View 3D Structure Click here
Q4CT82 View 3D Structure Click here
Q4CTQ6 View 3D Structure Click here
Q4CUH7 View 3D Structure Click here
Q4CVS4 View 3D Structure Click here
Q4CVS5 View 3D Structure Click here
Q4CVZ7 View 3D Structure Click here
Q4CW39 View 3D Structure Click here
Q4CW95 View 3D Structure Click here
Q4CWC5 View 3D Structure Click here
Q4CWC8 View 3D Structure Click here
Q4CX14 View 3D Structure Click here
Q4CXC1 View 3D Structure Click here
Q4CXQ0 View 3D Structure Click here
Q4CXV0 View 3D Structure Click here
Q4CXY7 View 3D Structure Click here
Q4CY76 View 3D Structure Click here
Q4CYW1 View 3D Structure Click here
Q4CZ65 View 3D Structure Click here
Q4CZ79 View 3D Structure Click here
Q4CZ90 View 3D Structure Click here
Q4CZA0 View 3D Structure Click here
Q4CZE6 View 3D Structure Click here
Q4CZJ4 View 3D Structure Click here
Q4CZP0 View 3D Structure Click here
Q4D070 View 3D Structure Click here
Q4D095 View 3D Structure Click here
Q4D098 View 3D Structure Click here
Q4D0A1 View 3D Structure Click here
Q4D0F0 View 3D Structure Click here
Q4D0T2 View 3D Structure Click here
Q4D1C1 View 3D Structure Click here
Q4D1D2 View 3D Structure Click here
Q4D2E7 View 3D Structure Click here
Q4D2F9 View 3D Structure Click here
Q4D2I1 View 3D Structure Click here
Q4D2L1 View 3D Structure Click here
Q4D2P3 View 3D Structure Click here
Q4D2W7 View 3D Structure Click here
Q4D371 View 3D Structure Click here
Q4D387 View 3D Structure Click here
Q4D3Q8 View 3D Structure Click here
Q4D495 View 3D Structure Click here
Q4D5C6 View 3D Structure Click here
Q4D5F2 View 3D Structure Click here
Q4D645 View 3D Structure Click here
Q4D696 View 3D Structure Click here
Q4D6K1 View 3D Structure Click here
Q4D6Y6 View 3D Structure Click here
Q4D781 View 3D Structure Click here
Q4D7D4 View 3D Structure Click here
Q4D7Z4 View 3D Structure Click here
Q4D859 View 3D Structure Click here
Q4D860 View 3D Structure Click here
Q4D8J4 View 3D Structure Click here
Q4D9A3 View 3D Structure Click here
Q4D9F2 View 3D Structure Click here
Q4DAA3 View 3D Structure Click here
Q4DAK1 View 3D Structure Click here
Q4DBC6 View 3D Structure Click here
Q4DBF0 View 3D Structure Click here
Q4DBZ5 View 3D Structure Click here
Q4DCP9 View 3D Structure Click here
Q4DD60 View 3D Structure Click here
Q4DD62 View 3D Structure Click here
Q4DDR1 View 3D Structure Click here
Q4DDR3 View 3D Structure Click here
Q4DDR4 View 3D Structure Click here
Q4DDV0 View 3D Structure Click here
Q4DE01 View 3D Structure Click here
Q4DE94 View 3D Structure Click here
Q4DEI6 View 3D Structure Click here
Q4DEK8 View 3D Structure Click here
Q4DEZ7 View 3D Structure Click here
Q4DF31 View 3D Structure Click here
Q4DF74 View 3D Structure Click here
Q4DFJ4 View 3D Structure Click here
Q4DGC5 View 3D Structure Click here
Q4DGI9 View 3D Structure Click here
Q4DGS3 View 3D Structure Click here
Q4DGV0 View 3D Structure Click here
Q4DGV9 View 3D Structure Click here
Q4DGZ1 View 3D Structure Click here
Q4DGZ2 View 3D Structure Click here
Q4DH26 View 3D Structure Click here
Q4DH72 View 3D Structure Click here
Q4DH92 View 3D Structure Click here
Q4DIL9 View 3D Structure Click here
Q4DIN1 View 3D Structure Click here
Q4DJ88 View 3D Structure Click here
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Q4DJE0 View 3D Structure Click here
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Q4DJR7 View 3D Structure Click here
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Q4DJS3 View 3D Structure Click here
Q4DK50 View 3D Structure Click here
Q4DK85 View 3D Structure Click here
Q4DKJ9 View 3D Structure Click here
Q4DKL5 View 3D Structure Click here
Q4DKM6 View 3D Structure Click here
Q4DLA2 View 3D Structure Click here
Q4DLB4 View 3D Structure Click here
Q4DLD0 View 3D Structure Click here
Q4DLM7 View 3D Structure Click here
Q4DM98 View 3D Structure Click here
Q4DMA4 View 3D Structure Click here
Q4DMN7 View 3D Structure Click here
Q4DN58 View 3D Structure Click here
Q4DN62 View 3D Structure Click here
Q4DN86 View 3D Structure Click here
Q4DNF9 View 3D Structure Click here
Q4DNP2 View 3D Structure Click here
Q4DP77 View 3D Structure Click here
Q4DP82 View 3D Structure Click here
Q4DPT5 View 3D Structure Click here
Q4DQ09 View 3D Structure Click here
Q4DQ76 View 3D Structure Click here
Q4DQA0 View 3D Structure Click here
Q4DQJ9 View 3D Structure Click here
Q4DQR8 View 3D Structure Click here
Q4DQW8 View 3D Structure Click here
Q4DRK0 View 3D Structure Click here
Q4DRK4 View 3D Structure Click here
Q4DRZ7 View 3D Structure Click here
Q4DSG4 View 3D Structure Click here
Q4DSY8 View 3D Structure Click here
Q4DTC3 View 3D Structure Click here
Q4DTK7 View 3D Structure Click here
Q4DTL7 View 3D Structure Click here
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Q4DV25 View 3D Structure Click here
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Q4DX98 View 3D Structure Click here
Q4DXP2 View 3D Structure Click here
Q4DY86 View 3D Structure Click here
Q4DY89 View 3D Structure Click here
Q4DYS5 View 3D Structure Click here
Q4DYT7 View 3D Structure Click here
Q4E026 View 3D Structure Click here
Q4E0A5 View 3D Structure Click here
Q4E0C8 View 3D Structure Click here
Q4E0I8 View 3D Structure Click here
Q4E0J0 View 3D Structure Click here
Q4E0J2 View 3D Structure Click here
Q4E0J3 View 3D Structure Click here
Q4E0J4 View 3D Structure Click here
Q4E0J5 View 3D Structure Click here
Q4E199 View 3D Structure Click here
Q4E1F0 View 3D Structure Click here
Q4E1H0 View 3D Structure Click here
Q4E203 View 3D Structure Click here
Q4E204 View 3D Structure Click here
Q4E222 View 3D Structure Click here
Q4E2A1 View 3D Structure Click here
Q4E373 View 3D Structure Click here
Q4E377 View 3D Structure Click here
Q4E383 View 3D Structure Click here
Q4E3D0 View 3D Structure Click here
Q4E3D7 View 3D Structure Click here
Q4E3E8 View 3D Structure Click here
Q4E424 View 3D Structure Click here
Q4E431 View 3D Structure Click here
Q4E469 View 3D Structure Click here
Q4E4X9 View 3D Structure Click here
Q4E4Z5 View 3D Structure Click here
Q4E504 View 3D Structure Click here
Q4E520 View 3D Structure Click here
Q4E533 View 3D Structure Click here
Q4E5K7 View 3D Structure Click here
Q4E5L3 View 3D Structure Click here
Q4E5S9 View 3D Structure Click here
Q4E5U1 View 3D Structure Click here
Q4E5U3 View 3D Structure Click here
Q4E5U7 View 3D Structure Click here
Q4E5V0 View 3D Structure Click here
Q4E5W0 View 3D Structure Click here
Q54IT4 View 3D Structure Click here
Q54U63 View 3D Structure Click here
Q55FA8 View 3D Structure Click here
Q56XZ1 View 3D Structure Click here
Q61245 View 3D Structure Click here
Q6Q0N0 View 3D Structure Click here
Q6QNK2 View 3D Structure Click here
Q80T32 View 3D Structure Click here
Q8I5L9 View 3D Structure Click here
Q8IBM1 View 3D Structure Click here
Q8IM24 View 3D Structure Click here
Q9EPL2 View 3D Structure Click here