Summary: Acetyltransferase (GNAT) domain
This is the Wikipedia entry entitled "Acetyltransferase". More...
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Acetyltransferase Edit Wikipedia article
- Histone acetyltransferases including CBP histone acetyltransferase
- Choline acetyltransferase
- Chloramphenicol acetyltransferase
- Serotonin N-acetyltransferase
- NatA Acetyltransferase
- NatB acetyltransferase
|This enzyme-related article is a stub. You can help Wikipedia by expanding it.|
Acetyltransferase (GNAT) domain Provide feedback
This family contains proteins with N-acetyltransferase functions.
Internal database links
|Similarity to PfamA using HHSearch:||FemAB FemAB_like ATE_C Mig-14 DUF2156|
External database links
This tab holds annotation information from the InterPro database.
No InterPro data for this Pfam family.
- the number of sequences which exhibit this architecture
a textual description of the architecture, e.g. Gla, EGF x 2, Trypsin.
This example describes an architecture with one
Gladomain, followed by two consecutive
EGFdomains, and finally a single
- the UniProt description of the protein sequence
- the number of residues in the sequence
- the Pfam graphic itself.
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This clan contains families related to N-acetyltransferases. N-acetyltransferases catalyse the transfer of acetyl groups from acetyl-CoA to arylamines.
The clan contains the following 33 members:Acetyltransf_1 Acetyltransf_10 Acetyltransf_13 Acetyltransf_15 Acetyltransf_3 Acetyltransf_4 Acetyltransf_5 Acetyltransf_6 Acetyltransf_7 Acetyltransf_8 Acetyltransf_9 Acetyltransf_CG AstA ATE_C ATE_N Autoind_synth DUF1248 DUF1999 DUF2156 DUF3749 FemAB FemAB_like FR47 Gly_acyl_tr_C GNAT_acetyltr_2 GNAT_acetyltran Leu_Phe_trans Mec-17 Mig-14 MOZ_SAS NAT NMT NodA
We make a range of alignments for each Pfam-A family:
- the curated alignment from which the HMM for the family is built
- the alignment generated by searching the sequence database using the HMM
- Representative Proteomes (RPs) at 15%, 35%, 55% and 75% co-membership thresholds
- alignment generated by searching the NCBI sequence database using the family HMM
- alignment generated by searching the metagenomics sequence database using the family HMM
You can see the alignments as HTML or in three different sequence viewers:
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- an HTML-based viewer that uses DAS to retrieve alignment fragments on request
1Cannot generate PP/Heatmap alignments for seeds; no PP data available
Key: available, not generated, — not available.
Format an alignment
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Curation and family details
|Number in seed:||143|
|Number in full:||5308|
|Average length of the domain:||142.00 aa|
|Average identity of full alignment:||21 %|
|Average coverage of the sequence by the domain:||29.02 %|
|HMM build commands:||
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 80369284 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||2|
|Download:||download the raw HMM for this family|
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The tree shows the occurrence of this domain across different species. More...
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