Summary: Toxin Ldr, type I toxin-antitoxin system
This is the Wikipedia entry entitled "RdlD RNA". More...
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Toxin Ldr, type I toxin-antitoxin system Provide feedback
This family includes the Ldr (long direct repeat) toxins. In Escherichia coli there are four Ldr toxins, LdrA, LdrB, LdrC and LdrD. These toxins inhibit cell growth, decrease cell viability and cause nucleoid condensation. LdrD expression is inhibited by the antisense RNA RdlD, which functions as an antitoxin .
Kawano M, Oshima T, Kasai H, Mori H;, Mol Microbiol. 2002;45:333-349.: Molecular characterization of long direct repeat (LDR) sequences expressing a stable mRNA encoding for a 35-amino-acid cell-killing peptide and a cis-encoded small antisense RNA in Escherichia coli. PUBMED:12123448 EPMC:12123448
External database links
This tab holds annotation information from the InterPro database.
InterPro entry IPR025253
This family includes the Ldr (long direct repeat) toxins. In Escherichia coli there are four Ldr toxins, LdrA, LdrB, LdrC and LdrD. These toxins inhibit cell growth, decrease cell viability and cause nucleoid condensation. They are part of the type I toxin antitoxin (TA) system, where expression of the proteinaceous toxin is controlled by an antisense sRNA. For example, LdrD expression is inhibited by the antisense RNA RdlD, which functions as an antitoxin [PUBMED:12123448].
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|Number in seed:||2|
|Number in full:||6152|
|Average length of the domain:||34.80 aa|
|Average identity of full alignment:||72 %|
|Average coverage of the sequence by the domain:||77.21 %|
|HMM build commands:||
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 80369284 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||2|
|Download:||download the raw HMM for this family|
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